Harrison E. Smith

ORCID: 0000-0003-1490-2307
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About
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Research Areas
  • Botany and Plant Ecology Studies
  • Forest Insect Ecology and Management
  • Collembola Taxonomy and Ecology Studies
  • Polymer-Based Agricultural Enhancements
  • Plant Parasitism and Resistance
  • CRISPR and Genetic Engineering
  • Histone Deacetylase Inhibitors Research
  • Cardiovascular Function and Risk Factors
  • Composting and Vermicomposting Techniques
  • Animal Disease Management and Epidemiology
  • Marine Biology and Ecology Research
  • Zoonotic diseases and public health
  • Virus-based gene therapy research
  • Plant Disease Management Techniques
  • Cardiomyopathy and Myosin Studies
  • Forensic Entomology and Diptera Studies
  • Insect behavior and control techniques
  • Diptera species taxonomy and behavior
  • Bryophyte Studies and Records
  • Pesticide and Herbicide Environmental Studies
  • Berry genetics and cultivation research
  • Agricultural Practices and Plant Genetics
  • Pluripotent Stem Cells Research
  • GDF15 and Related Biomarkers
  • Mediterranean and Iberian flora and fauna

Baylor College of Medicine
2019-2021

Colorado School of Public Health
2021

United States Department of Agriculture
1915

Rationale: Small molecule inhibitors of the acetyl-histone binding protein BRD4 have been shown to block cardiac fibrosis in preclinical models heart failure (HF). However, since target ubiquitously, it is unclear whether this chromatin reader functions cell type-specific manner control pathological myocardial fibrosis. Furthermore, molecular mechanisms by which stimulates transcriptional program for remain unknown. Objective: We sought test hypothesis that a cell-autonomous and...

10.1161/circresaha.119.315125 article EN Circulation Research 2019-08-14

Background: Diastolic dysfunction (DD) is associated with the development of heart failure and contributes to pathogenesis other cardiac maladies, including atrial fibrillation. Inhibition histone deacetylases (HDACs) has been shown prevent DD by enhancing myofibril relaxation. We addressed therapeutic potential HDAC inhibition in a model established preserved ejection fraction. Methods: Four weeks after uninephrectomy implantation deoxycorticosterone acetate pellets, when was clearly...

10.1161/circulationaha.120.046462 article EN Circulation 2021-03-08

Journal Article Broom Corn, the Probable Host in Which Pyrausta Nubilalis Hubn. Reached America Get access Harrison E. Smith U. S. Bureau of Entomology, Corn Borer Laboratory, Arlington, Mass. Search for other works by this author on: Oxford Academic PubMed Google Scholar Economic Volume 13, Issue 5, 1 October 1920, Pages 425–430, https://doi.org/10.1093/jee/13.5.425 Published: 01 1920

10.1093/jee/13.5.425 article EN Journal of Economic Entomology 1920-10-01

Clinical application of somatic genome editing requires therapeutics that are generalizable to a broad range patients. Targeted insertion promoterless transgenes can ensure edits permanent and broadly applicable while minimizing risks off-target integration. In the liver, Albumin (Alb) locus is currently only well-characterized site for transgene insertion. Here, we target Apoa1 with adeno-associated viral (AAV) delivery CRISPR-Cas9 achieve rates 6% 16% targeted hepatocytes, no evidence...

10.1016/j.omtm.2021.04.011 article EN cc-by-nc-nd Molecular Therapy — Methods & Clinical Development 2021-04-24

Sigaloissa frontalis sp.nov.c.Front wider than one eye, shining black, a narrow silvery line on each side of the ocellar triangle, beginning at declivity occiput and continuing straight forward half length front; anterior fourth front yellow; compound eyes not limiting vertex laterally, it being nearly twice as wide ending in point way; antennae yellow, third joint brown apical or more, with upcurved short dense pale hair; arista short-plumose, about dozen rays; face concave, slight whitish...

10.1155/1915/10341 article EN public-domain Psyche A Journal of Entomology 1915-01-01

Following are the descriptions of five new species Tachinide

10.1155/1917/89159 article EN Psyche A Journal of Entomology 1917-01-01

Abstract The feasibility of producing soil‐conditioning agents from agricultural residues by chemical modification was investigated. Such reactions as xanthation, cyanoethylation, methylation, hydroxyethylation, sulfation, phosphorylation, acetylation, and oxidation were applied to wheat straw, corn stover, corncobs, bagasse, rice hulls, their major components. From results comparative on cellulose, hemicellulose, lignin, the part activity chemically‐modified found attributable substituted...

10.2136/sssaj1958.03615995002200050011x article EN Soil Science Society of America Journal 1958-09-01

Pseudotachinomyia gen

10.1155/1917/91575 article CA public-domain Psyche A Journal of Entomology 1917-01-01

An abstract is not available for this content so a preview has been provided. Please use the Get access link above information on how to content.

10.4039/ent47153-5 article EN The Canadian Entomologist 1915-05-01

Introduction: Diastolic dysfunction is associated with the development of heart failure preserved ejection fraction and other cardiac maladies, including atrial fibrillation. Inhibition histone deacetylase (HDAC) activity has previously been shown to prevent diastolic by enhancing myofibril relaxation. Here, we further addressed therapeutic potential HDAC inhibition in a model established fraction. Methods: Four weeks following uninephrectomy (UNX) implantation deoxycorticosterone acetate...

10.1161/circ.142.suppl_3.15707 article EN Circulation 2020-11-17
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