A5081566432- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Trigeminal Neuralgia and Treatments
- Transcranial Magnetic Stimulation Studies
- Migraine and Headache Studies
- Musculoskeletal pain and rehabilitation
- Pain Management and Treatment
- Pain Management and Placebo Effect
- Facial Nerve Paralysis Treatment and Research
- Vestibular and auditory disorders
- Peripheral Neuropathies and Disorders
- Neurological disorders and treatments
- Laser Applications in Dentistry and Medicine
- Peripheral Nerve Disorders
- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- Ophthalmology and Eye Disorders
- Temporomandibular Joint Disorders
- Dental Anxiety and Anesthesia Techniques
- Pain Management and Opioid Use
- EEG and Brain-Computer Interfaces
- Advanced Neuroimaging Techniques and Applications
- Epilepsy research and treatment
- Cancer Treatment and Pharmacology
- Fibromyalgia and Chronic Fatigue Syndrome Research
Sapienza University of Rome
2015-2024
VA Connecticut Healthcare System
2021
University of Bari Aldo Moro
2005-2019
Università Campus Bio-Medico
2019
Heidelberg University
2016
European Association of Nuclear Medicine
2016
International Association for the Study of Pain
2016
Aarhus University
2016
University of Liverpool
2008-2016
Danish Pain Research Center
2016
Pain usually results from activation of nociceptive afferents by actually or potentially tissue-damaging stimuli. may also arise activity generated within the nervous system without adequate stimulation its peripheral sensory endings. For this type pain, International Association for Study introduced term neuropathic defined as "pain initiated caused a primary lesion dysfunction in system." While definition has been useful distinguishing some characteristics and types it lacks boundaries....
Neuropathic pain treatment remains unsatisfactory despite a substantial increase in the number of trials. This EFNS Task Force aimed at evaluating existing evidence about pharmacological neuropathic pain. Studies were identified using first Cochrane Database then Medline. Trials classified according to aetiological condition. All class I and II controlled trials (according classification evidence) assessed, but lower-class studies considered conditions that had no top level studies. Only...
1. The silent period evoked in the first dorsal interosseous (FDI) muscle after electrical and magnetic transcranial stimulation (TCS), of cervicomedullary junction ulnar nerve was studied ten healthy subjects. 2. With maximum‐intensity shocks, average duration 200 ms TCS, 300 43 at 100 peripheral stimulation. 3. period, amplitude motor‐evoked potential, twitch force produced were compared increasing intensities TCS. When stimulus strength increased from 30 to 70% stimulator output,...
Several issues regarding diagnosis, pharmacological treatment, and surgical treatment of trigeminal neuralgia (TN) are still unsettled. The American Academy Neurology the European Federation Neurological Societies launched a joint Task Force to prepare general guidelines for management this condition. After systematic review literature came series evidence-based recommendations. In patients with TN MRI may be considered identify structural causes. presence sensory deficits, bilateral...
Pharmacological relief of neuropathic pain is often insufficient. Electrical neurostimulation efficacious in chronic and other neurological diseases. European Federation Neurological Societies (EFNS) launched a Task Force to evaluate the evidence for these techniques produce relevant recommendations. We searched literature from 1968 2006, looking conditions, classified trials according EFNS scheme therapeutic interventions. Spinal cord stimulation (SCS) failed back surgery syndrome (FBSS)...
Abstract Patients with neuropathic pain are heterogeneous in etiology, pathophysiology, and clinical appearance. They exhibit a variety of pain-related sensory symptoms signs (sensory profile). Different profiles might indicate different classes neurobiological mechanisms, hence subgroups respond differently to treatment. The aim the investigation was identify large sample patients using hypothesis-free statistical methods on database 3 multinational research networks (German Research...
In September 2001, a Task Force was set up under the auspices of European Federation Neurological Societies with aim evaluating existing evidence about methods assessing neuropathic pain and its treatments. This review led to development guidelines be used in management patients pain. clinical setting neurological examination that includes an accurate sensory is often sufficient reach diagnosis. Nerve conduction studies somatosensory‐evoked potentials, which do not assess small fibre...
Trigeminal neuralgia (TN) is an extremely painful condition which can be difficult to diagnose and treat. In Europe, TN patients are managed by many different specialities. Therefore, there a great need for comprehensive European guidelines the management of TN. The Academy Neurology asked expert panel develop recommendations series questions that essential daily clinical with TN.A systematic review literature was performed developed based on GRADE, where feasible; if not, good practice...
This multicentre, double-blind, parallel-group study in diabetic peripheral neuropathic pain addressed whether, patients not responding to standard doses of duloxetine or pregabalin, combining both medications is superior increasing each drug its maximum recommended dose. For initial 8-week therapy, either 60 mg/day (groups 1, 2) 300 pregabalin 3, 4) was given. Thereafter, the combination/high-dose therapy period, only nonresponders received 120 (group 1), a combination and 2, 3), 600 4)....