A5037252168- Economic and Environmental Valuation
- Transportation Planning and Optimization
- Decision-Making and Behavioral Economics
- Gender, Labor, and Family Dynamics
- Urban Transport and Accessibility
- Motor Control and Adaptation
- Transportation and Mobility Innovations
- Retinoids in leukemia and cellular processes
- Estrogen and related hormone effects
- Housing Market and Economics
- Neuroscience of respiration and sleep
- Muscle activation and electromyography studies
- Neural dynamics and brain function
- Social Policies and Family
- Regional Economics and Spatial Analysis
- Neuroscience and Neuropharmacology Research
- Social Sciences and Governance
- Economics of Agriculture and Food Markets
- Spatial and Panel Data Analysis
- COVID-19 Pandemic Impacts
- Intergenerational and Educational Inequality Studies
- Fiscal Policy and Economic Growth
- Income, Poverty, and Inequality
- Consumer Market Behavior and Pricing
- Ubiquitin and proteasome pathways
Bureau d'Economie Théorique et Appliquée
2021-2025
Université de Strasbourg
2021-2025
Université de Lorraine
2021-2025
University of Pittsburgh
2001-2024
Institut de Biologie Valrose
2021
Université Côte d'Azur
2021
Centre National de la Recherche Scientifique
2007-2021
Observatoire de la Côte d’Azur
2021
Center for the Neural Basis of Cognition
2003-2020
Boston Children's Hospital
2014-2019
The acquisition of motor skills can lead to profound changes in the functional organization primary cortex (M1). For example, performance movement sequences after prolonged practice is associated with an expansion effector representation M1. Paradoxically, there little evidence that activity M1 neurons reflects acquired skills, especially movements. We examined during skilled macaques trained successively hit targets on a monitor. appeared either pseudorandomly (Random mode) or one two...
The supplementary motor area (SMA) has long been thought to have a special role in the internal generation of complex movements. Yet, number recent functional imaging studies indicate that SMA is activated during execution simple movements guided by sensory cues. extent participation cingulate areas visually also unclear. To explore these issues we used 2-deoxyglucose (2DG) technique measure activation on medial wall hemisphere monkeys trained perform reaching randomly presented targets....
Ketamine has emerged as a widespread treatment for variety of psychiatric disorders when used at sub-anesthetic doses, but the neural mechanisms underlying its acute action remain unclear. Here, we identified NMDA receptors containing 2A subunit (GluN2A) on parvalbumin (PV)-expressing inhibitory interneurons pivotal target low-dose ketamine. Genetically deleting GluN2A globally or selectively from PV abolished rapid enhancement visual cortical responses and gamma-band oscillations by...
1. Two monkeys were trained to grasp an object between the thumb and index finger lift it a vertical distance of 12-25 mm. Up 12 different conditions defined by combinations weights (15, 65, 115 g) four surface textures (oiled metal, smooth fine coarse sandpaper) used. The apparatus was equipped measure grip (prehensile) force, (load) displacement. 2. appropriately scaled force for weight coefficient friction object. However, during dynamic phase task (grasping lifting), increased prehensile...
Information about traffic conditions has traditionally been conveyed to drivers via radio, variable message signs, and, more recently, the Internet and advanced traveler information systems. This spurred research on how travelers respond information, much they are willing pay for it, likely benefit from it collectively. In this paper, we analyze decisions of whether acquire which routes take simple congested road networks. Drivers vary in their degrees risk aversion with respect travel time....
As skill on a sequence of movements is acquired through practice, each movement in the becomes seamlessly associated with another. To study neural basis skills, we trained two monkeys ( Cebus apella ) to perform sequential reaching tasks. In one task, were instructed by visual cues, whereas other generated from memory after extended practice. Then, examined activity dorsal premotor area (PMd) and effects its local inactivation during performance task. Comparable numbers neurons PMd active...
1. Two monkeys were trained to grasp, lift, and hold an object within a vertical position window. A downward force-pulse perturbation was delivered during stationary holding simulate slip of the due gravity. The responses evoked by studied in 189 neurons hand area primary motor cortex. In addition, slip-evoked compared with modulation neural discharge textures weights described previous paper. 2. sharp onsets majority cortical (115/189, 61%) active task. sufficiently short latency (43.17 +/-...
This article reports results of an experiment designed to analyze the link between risky decisions made by couples and separately each spouse. We estimate both spouses couples' degrees risk aversion, we assess how preferences two aggregate when they make decisions, shed light on dynamics decision process that takes place decisions. find that, far from being fixed, balance power within household is malleable. In most couples, men have, initially, more decision-making than women but who...
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SUMO conjugation has emerged as a dynamic process in regulating protein function. Here we identify estrogen receptor β (ERβ) to be new target of SUMO-1. ERβ SUMO-1 modification occurs on unique nonconsensus sumoylation motif which becomes fully competent upon phosphorylation its contained serine residue, provides the essential negative charge for sumoylation. This is further regulated by additional adjacent residues glycogen synthase kinase 3β (GSK3β), maximizes response hormone. attachment...
Sequence production tasks are a standard tool to analyze motor learning, consolidation, and habituation. As sequences learned, movements typically grouped into subsets or chunks. For example, most Americans memorize telephone numbers in two chunks of three digits, one chunk four. Studies generally use response times error rates estimate how subjects chunk, these estimates often related physiological data. Here we show that chunking is simultaneously reflected reaction times, errors, their...