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Lyanna Rodrigues Ribeiro

ORCID: 0000-0003-1576-6167
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A5062671981
Research Areas
  • Synthesis and Biological Evaluation
  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Bioactive Compounds and Antitumor Agents
  • Synthesis and biological activity
  • Agricultural and Food Sciences
  • Nanoparticles: synthesis and applications
  • Essential Oils and Antimicrobial Activity
  • Neutropenia and Cancer Infections
  • Click Chemistry and Applications
  • Cancer therapeutics and mechanisms
  • Oral health in cancer treatment
  • Global Public Health Policies and Epidemiology
  • Cholinesterase and Neurodegenerative Diseases
  • Nonlinear Optical Materials Research
  • Computational Drug Discovery Methods
  • Health, Nursing, Elderly Care
  • Fish biology, ecology, and behavior

Universidade Federal do Ceará
 2021-2024

 Synthesis, Vibrational Analysis, Thermal analysis, Quantum-chemical Calculation, Molecular Docking and Dynamics, DMPK and Evaluation of the Antichagasic Potential of a Fluorinated Chalcone
OPENALEX - Publications 
João Victor Serra Nunes Emanuelle Machado Marinho Caio Henrique Alexandre Roberto Ramon Róseo Paula Pessoa Bezerra de Menezes Emanuel Paula Magalhães and 9 more Lyanna Rodrigues Ribeiro Matheus Nunes da Rocha Francisco Wagner Queiroz Almeida-Neto Marília Lopes Monteiro Emmanuel Silva Marinho Alexandre Magno Rodrigues Teixeira Márcia Machado Marinho Alice Maria Costa Martins Hélcio Silva dos Santos

10.1016/j.molstruc.2024.139124 article EN Journal of Molecular Structure 2024-07-10
 Insights of potential trypanocidal effect of the synthetic derivative (2E)-1-(4-aminophenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one: in vitro assay, MEV analysis, quantum study, molecular docking, molecular dynamics, MPO analysis, and predictive ADMET
OPENALEX - Publications 
Márcia Machado Marinho Matheus Nunes da Rocha Emanuel Paula Magalhães Lyanna Rodrigues Ribeiro Caio Henrique Alexandre Roberto and 8 more Francisco Wagner Queiroz Almeida-Neto Marília Lopes Monteiro João Victor Serra Nunes Ramon Róseo Paula Pessoa Bezerra de Menezes Emmanuel Silva Marinho Pedro de Lima‐Neto Alice Maria Costa Martins Hélcio Silva dos Santos

10.1007/s00210-024-03138-z article EN Naunyn-Schmiedeberg s Archives of Pharmacology 2024-05-09
 Chloride substitution on 2-hydroxy-3,4,6-trimethoxyphenylchalcones improves in vitro selectivity on Trypanosoma cruzi strain Y
OPENALEX - Publications 
Emanuel Paula Magalhães Naiara Dutra Barroso Gomes Tiago Araújo de Freitas Brenna Pinheiro Silva Lyanna Rodrigues Ribeiro and 9 more Francisco Wagner Queiroz Ameida-Neto Márcia Machado Marinho Pedro de Lima‐Neto Emmanuel Silva Marinho Hélcio Silva dos Santos Alexandre Magno Rodrigues Teixeira Tiago Lima Sampaio Ramon Róseo Paula Pessoa Bezerra de Menezes Alice Maria Costa Martins

10.1016/j.cbi.2022.109920 article EN Chemico-Biological Interactions 2022-04-21
 Synthesis, structural and spectroscopic analysis, and antiproliferative activity of chalcone derivate (E)-1-(4-aminophenyl)-3-(benzo[b]thiophen-2-yl)prop‑2-en-1-one in Trypanosoma cruzi
OPENALEX - Publications 
Débora Hellen Almeida de Brito Francisco Wagner Queiroz Almeida-Neto Lyanna Rodrigues Ribeiro Emanuel Paula Magalhães Ramon Róseo Paula Pessoa Bezerra de Menezes and 12 more Tiago Lima Sampaio Alice Maria Costa Martins Paulo Nogueira Bandeira Márcia Machado Marinho Emmanuel Silva Marinho Antônio C.H. Barreto Pedro de Lima‐Neto Gilberto D. Saraiva Kirley Marques Canuto Hélcio Silva dos Santos Alexandre Magno Rodrigues Teixeira Nágila Maria Pontes Silva Ricardo

10.1016/j.molstruc.2021.132197 article EN Journal of Molecular Structure 2021-12-18
 Paraprobiotic Enterococcus faecalis EC-12 prevents the development of irinotecan-induced intestinal mucositis in mice
OPENALEX - Publications 
Lívia Maria Soares Nobre Marina Helena da Silva Lopes Juliana Geraix Aurilene Gomes Cajado Jussara Matyelle Rodrigues Silva and 6 more Lyanna Rodrigues Ribeiro Rosemayre Souza Freire Diane Isabelle Magno Cavalcante Deysi Viviana Tenazoa Wong Ana Paula Negreiros Nunes Alves Roberto César Pereira Lima‐Júnior

10.1016/j.lfs.2022.120445 article EN publisher-specific-oa Life Sciences 2022-03-02
 Quantum mechanical, molecular docking, molecular dynamics, ADMET and antiproliferative activity onTrypanosoma cruzi(Y strain) of chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3-nitrophenyl)prop-2-en-1-one derived from a natural product
OPENALEX - Publications 
Maria Geysillene Castro Matos Leonardo Paes da Silva Francisco Wagner Queiroz Almeida-Neto Emanuelle Machado Marinho Ramon Róseo Paula Pessoa Bezerra de Menezes and 11 more Tiago Lima Sampaio Matheus Nunes da Rocha Lyanna Rodrigues Ribeiro Emanuel Paula Magalhães Alexandre Magno Rodrigues Teixeira Hélcio Silva dos Santos Emmanuel Silva Marinho Pedro de Lima‐Neto Alice Maria Costa Martins Norberto de Kássio Vieira Monteiro Márcia Machado Marinho

Chagas disease is a leading public health problem. More than 8 million people are affected by the disease, which endemic in 21 countries Latin America, generating an average annual cost of 7.2 billion dollars per year. The conventional treatment carried out administering drug benznidazole (BZN), has caused numerous adverse reactions. Hence, search for new, more efficient, and less toxic anti-chagasic agents essential. Recently, chalcones have been researched to propose new therapies against...

10.1039/d1cp04992e article EN Physical Chemistry Chemical Physics 2022-01-01
 Antibacterial and antibiotic modifying activity of chalcone (2E)-1-(4′-aminophenyl)-3-(4-methoxyphenyl)-prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps: In vitro and in silico approaches
OPENALEX - Publications 
Jacilene Silva Janaína Esmeraldo Rocha Jayze da Cunha Xavier Thiago Sampaio de Freitas Henrique Douglas Melo Coutinho and 11 more Paulo Nogueira Bandeira Mateus Rodrigues de Oliveira Matheus Nunes da Rocha Emanuelle Machado Marinho Norberto de Kássio Vieira Monteiro Lyanna Rodrigues Ribeiro Ramon Róseo Paula Pessoa Bezerra de Menezes Márcia Machado Marinho Alexandre Magno Rodrigues Teixeira Hélcio Silva dos Santos Emmanuel Silva Marinho

10.1016/j.micpath.2022.105664 article EN Microbial Pathogenesis 2022-07-05
 Trypanocidal potential of synthetic p-aminochalcones: In silico and in vitro evaluation
OPENALEX - Publications 
Naiara Dutra Barroso Gomes Emanuel Paula Magalhães Lyanna Rodrigues Ribeiro John Washington Cavalcante Marcelo Morais Gomes Maia and 7 more Felipe Ramon Cunha da Silva Arif Ali Márcia Machado Marinho Emmanuel Silva Marinho Hélcio Silva dos Santos Alice Maria Costa Martins Ramon Róseo Paula Pessoa Bezerra de Menezes

10.1016/j.bioorg.2023.106931 article EN Bioorganic Chemistry 2023-10-20
 (−)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B
OPENALEX - Publications 
Emanuel Paula Magalhães Brenna Pinheiro Silva Natália Luna Aires Lyanna Rodrigues Ribeiro Arif Ali and 5 more Mariana Maciel Cavalcanti João Victor Serra Nunes Tiago Lima Sampaio Ramon Róseo Paula Pessoa Bezerra de Menezes Alice Maria Costa Martins

10.1016/j.lfs.2021.120271 article EN Life Sciences 2021-12-30
 Elongation on Aliphatic Chain Improves Selectivity of 2-Hydroxy-3,4,6-Trimethoxyphenyl Chalcone on Trypanosoma Cruzi
OPENALEX - Publications 
Lyanna Rodrigues Ribeiro Emanuel Paula Magalhães Naiara Dutra Barroso Gomes John Washington Cavalcante Marcelo Morais Gomes Maia and 6 more Márcia Machado Marinho Hélcio Silva dos Santos Emmanuel Silva Marinho Tiago Lima Sampaio Alice Maria Costa Martins Ramon Róseo Paula Pessoa Bezerra de Menezes

Our objective was to investigate the trypanocidal effect of chalcone (2

10.4155/fmc-2023-0177 article EN Future Medicinal Chemistry 2023-12-12
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