A5061095280- COVID-19 Clinical Research Studies
- Gastric Cancer Management and Outcomes
- Axon Guidance and Neuronal Signaling
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Gastrointestinal Tumor Research and Treatment
- Angiogenesis and VEGF in Cancer
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- Biliary and Gastrointestinal Fistulas
- Hippo pathway signaling and YAP/TAZ
- Extracellular vesicles in disease
- Cancer Immunotherapy and Biomarkers
- Esophageal Cancer Research and Treatment
- Cancer Genomics and Diagnostics
- Neuroendocrine Tumor Research Advances
- HIV-related health complications and treatments
- Pancreatic and Hepatic Oncology Research
- Immune Response and Inflammation
- Inflammasome and immune disorders
- Lipoproteins and Cardiovascular Health
- Myasthenia Gravis and Thymoma
- Cardiovascular Function and Risk Factors
National and Kapodistrian University of Athens
2021-2025
Laiko General Hospital of Athens
2021-2025
Hepatocellular carcinoma (HCC) remains a global health challenge with limited treatment options and poor prognosis for advanced-stage patients. Recent advancements in cancer immunotherapy have generated significant interest exploring novel approaches to combat HCC. One such approach involves the unique versatile subset of T cells known as γδ cells. represent distinct lymphocytes that differ from conventional αβ terms antigen recognition effector functions. They play crucial role...
Esophageal cancer (EC) remains a formidable malignancy with limited treatment options and high mortality rates, necessitating the exploration of innovative therapeutic avenues. Through systematic analysis multitude studies, we synthesize diverse findings related to metformin’s influence on EC. This review comprehensively elucidates intricate metabolic pathways molecular mechanisms through which metformin may exert its anti-cancer effects. Key focus areas include impact insulin signaling,...
SARS-CoV-2, which emerged in Wuhan, China, is a new global threat that has killed millions of people and continues to do so. This pandemic not only threatened human life but also triggered economic downturns across the world. Researchers have made significant strides discovering molecular insights into SARSCoV- 2 pathogenesis developing vaccines, there still no successful cure for SARS-CoV-2 infected patients.The present study proposed drug-repositioning pipeline design discovery an...
Hepatocellular carcinoma (HCC) stands as a primary malignant liver tumor characterized by chronic inflammation and complex alterations within the microenvironment (TME). Lymphocyte activation gene 3 (LAG-3), also known CD223, has gained prominence potential next-generation immune checkpoint, maintaining continuous expression in response to persistent antigen exposure TME, warranting our attention. In patients with HCC, LAG-3 on T cells, regulatory cells (Tregs), natural killer (NK)...
Inflammasomes are multimeric protein complexes, sensors of intracellular danger signals, and crucial components the innate immune system, with NLRP3 inflammasome being best characterized among them. The increasing scientific interest in mechanisms interconnecting inflammation tumorigenesis has led to study setting various neoplasms. Despite a plethora data regarding solid tumors, inflammasome’s implication pathogenesis hematological malignancies only recently gained attention. In this...
Gut microbiota-derived metabolite Trimethylamine-N-oxide (TMAO) is increasingly recognized as a potential novel prognostic biomarker for cardiovascular disease. Our research work aimed to investigate the utility of TMAO measurement in patients with STelevation Myocardial Infarction (STEMI). We performed systematic literature search PubMed from inception 1st February 2024 identify all studies examining association between plasma levels and disease complexity or clinical outcomes STEMI...
Journal Article Accepted manuscript Drawing a line: Do we live to work? Get access Christos Tsagkaris, Tsagkaris European Student Think Tank, Public Health and Policy Working Group, Amsterdam, Netherlands Corresponding author: Netherlands; [email protected] Search for other works by this author on: Oxford Academic PubMed Google Scholar Stavros P Papadakos, Papadakos First Department of Pathology, Medical School, National Kapodistrian University Athens, 157 72, Greece Anna Loudovikou,...