A5041729513- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Cardiomyopathy and Myosin Studies
- Heart Rate Variability and Autonomic Control
- Poisoning and overdose treatments
- Cardiovascular Syncope and Autonomic Disorders
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular Effects of Exercise
- ECG Monitoring and Analysis
- Traumatic Brain Injury Research
- Aortic Disease and Treatment Approaches
- Sepsis Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Peripheral Nerve Disorders
- Transplantation: Methods and Outcomes
- Cardiac Valve Diseases and Treatments
- Gout, Hyperuricemia, Uric Acid
- Vascular Procedures and Complications
- Pharmaceutical studies and practices
- Ion channel regulation and function
- Lung Cancer Treatments and Mutations
MetroHealth Medical Center
2018-2024
Case Western Reserve University
2018-2024
MetroHealth
2023
Massachusetts General Hospital
2020
Clinical Research Institute
2020
Metro Health Hospital
2020
Virginia Tech
2016-2019
Carilion Clinic
2010-2019
Brown University
2010
Rhode Island Hospital
2010
Background— Right ventricular pacing (RVP) during supraventricular tachycardia produces progressive QRS fusion before the morphology becomes stable. This transition zone (TZ) may provide useful information for differentiating orthodromic reciprocating (ORT) from atrioventricular nodal reentrant and atrial independent of entrainment success. Methods Results— We studied effect properly timed RVP on timing TZ in 92 patients with who had within 40 ms cycle length. The includes progressively...
<b>Background:</b> To test the hypothesis that a high C reactive protein (CRP) concentration would predict recurrence of atrial fibrillation (AF) after cardioversion in patients taking antiarrhythmic drugs. <b>Methods:</b> 111 who underwent direct current for symptomatic AF were enrolled. Blood was drawn CRP determination before on same day. All drugs and electrical cardioversion. <b>Results:</b> After mean follow up 76 days, 75 had AF. In univariate analysis, median significantly higher...
Aims: Atrial fibrillation (AF) is the most common sustained arrhythmia. Previous evidence in animal models suggests that gap junction (GJ) adjacent nanodomain – perinexus a site capable of independent intercellular communication via ephaptic transmission. Perinexal expansion associated with slowed conduction and increased ventricular arrhythmias models, but has not been studied human tissue. The purpose this study was to characterize humans determine if perinexal associates AF. Methods:...
Objectives: We aimed to evaluate left atrial appendage (LAA) exclusion in patients undergoing mitral valve surgery with respect thromboembolic events. Background: LAA is the predominant source of emboli fibrillation. Prophylactic at time heart has been recommended reduce risk future thromboembolism. Methods: An observational cohort 136 during was identified between May 1993 and November 1998 our institution. Results: During a mean follow‐up 3.6 ± 1.3 years, there were 14 (12.3%) Compared who...
Background: The incidence of atrial fibrillation (AF) in heart transplant patients has not been well documented. Methods: To determine the AF a cohort undergoing cardiac transplantation, clinical data were obtained from prospectively collected database for all consecutive orthotopic transplantation (OHT) and coronary artery bypass graft (CABG) surgery between January 1984 March 2004 at our institution. A 1,714 OHT low‐risk CABG (normal ejection fraction [EF] no left ventricular hypertrophy...
Ventricular tachycardia (VT)/ventricular fibrillation (VF) rearrest after successful resuscitation is common, and survival poor. A mechanism of VT/VF, as demonstrated in ex vivo studies, when repolarization alternans becomes spatially discordant (DIS ALT), which can be enhanced by impaired gap junctions (GJs). However, spontaneous DIS ALT-induced VT/VF has never been demonstrated, the effects GJ on ALT are unknown.
The posterior wall (PW) has been proposed as a standard target for ablation beyond pulmonary vein antral isolation (PVI) in patients with persistent atrial fibrillation (AF). However, studies have shown inconsistent outcomes the addition of PW ablation. presence or absence low voltage on may explain these inconsistencies. We evaluated whether based improves long-term arrhythmia-free outcomes.We retrospectively reviewed 5-year follow-up 152 consecutive who received either (SA) PVI alone +...
Nerve conduction studies (NCS) may be deferred because of a perceived risk cardiac arrhythmia in the presence same-limb peripheral intravenous lines. Patients with implanted pacemakers or defibrillators provide model whom this can assessed. Twenty patients, seven and 13 defibrillators, had lines placed during routine care underwent NCS same limb. were performed line clamped then saline open to gravity. The device was interrogated before after study. During surface electrocardiogram...
A 32-year-old male developed recurrent ventricular tachycardia after taking mega doses of loperamide and famotidine in order to experience an opiate-like euphoric effect. He was up 200 mg multiple each day. palpitations syncope. Electrocardiography demonstrated QT interval prolongation (corrected 597 ms). diagnosed with loperamide-induced resulting incessant tachycardia. Loperamide discontinued, he treated electrolyte replacement, supportive care, monitoring. After 5 days, his...
The purpose of this study was to determine whether high-sensitivity C-reactive protein (hsCRP) levels differ among patients with acute aortic syndromes (AAS) and if hsCRP could predict their long-term outcomes.Retrospective observational study.Cleveland Clinic Hospital, Cleveland, Ohio.115 consecutive AAS admitted the cardiac intensive care unit.HsCRP other laboratory data were measured within 24 h admission. Demographic, imaging obtained at time presentation. For survival analysis, social...
Background Dofetilide is a class III antiarrhythmic drug effective for the treatment of atrial fibrillation (AF). initiation (DI) associates with corrected QT interval (QTc) prolongation. Significant QTc prolongation during DI mandates dose adjustment or discontinuation drug. Microsatellite DNA are novel genetic markers associated congenital and acquired health conditions. Hypothesis. microsatellite polymorphism may associate response to dofetilide in patients persistent AF. Methods We...