A5005198814- Luminescence Properties of Advanced Materials
- Nanoplatforms for cancer theranostics
- ZnO doping and properties
- Metal-Organic Frameworks: Synthesis and Applications
- Radiation Therapy and Dosimetry
- Luminescence and Fluorescent Materials
- Catalytic Processes in Materials Science
- Crystallization and Solubility Studies
- Photodynamic Therapy Research Studies
- X-ray Diffraction in Crystallography
- Ga2O3 and related materials
- Lanthanide and Transition Metal Complexes
- Machine Learning in Materials Science
- Advanced Radiotherapy Techniques
- Catalysis and Oxidation Reactions
- Gas Sensing Nanomaterials and Sensors
- Nanotechnology research and applications
- Radiation Shielding Materials Analysis
- Copper-based nanomaterials and applications
- Carbon Nanotubes in Composites
University of Milano-Bicocca
2019-2025
Large Stokes shift fast emitters show a negligible reabsorption of their luminescence, feature highly desirable for several applications such as fluorescence imaging, solar-light managing, and fabricating sensitive scintillating detectors medical imaging high-rate high-energy physics experiments. Here we obtain high efficiency luminescence with significant by exploiting fluorescent conjugated acene building blocks arranged in nanocrystals. Two ligands equal molecular length connectivity, yet...
Hybrid nanoscintillators, which feature a heavy inorganic nanoparticle conjugated with an organic emitter, represent promising avenue for advancements in diverse fields, including high-energy physics, homeland security, and biomedicine. Many research studies have shown the suitability of hybrid nanoscintillators radiation oncology, showing potential to improve therapeutic results compared traditional protocols. In this work, we studied SiO2/ZnO nanoparticles functionalized porphyrin as...
Nanomedicine is emerging as promising approach for the implementation of oncological methods. In this review, we describe most recent methods exploiting heavy nanoparticles and hybrid nanomaterials aiming at improving traditional X-rays-based treatments. High-Z are proposed radiosensitizers due to their ability stop ionizing radiation increase locally delivered therapeutic dose. Other working catalysts can generate reactive oxygen species upon X-rays exposure. Thanks high toxicity...
The present study aims at supplying a more in-depth picture of the generation environmentally persistent free radicals (EPFRs) from phenol (PhOH) on ZnO/SiO2 systems, by exploring properties ZnO nanoparticles (NPs) with different intrinsic defectivity grown highly porous silica spherical (ZnO/SiO2_S) and wormlike morphology (ZnO/SiO2_W). In detail, besides an extensive structural, morphological, surface investigation, occurrence inequivalent defect centers in samples was tracked...
This study addresses the relationship between material morphology (size, growth parameters and interfaces) optical emissions in ZnO through an experimental approach, including effect of different dimensions from bulk to nano-size, excitations, sources ionizing radiation. Silica supported nanoparticles ligand capped are synthesized a sol–gel process hot injection method, respectively. Their properties investigated by radioluminescence, steady-state time-resolved photoluminescence, compared...
As a model radio-photodynamic therapy (RPDT) agent, we developed multicomponent nanomaterial by anchoring conjugated chromophores on the surface of scintillating chrysotile nanotubes. Its ultimate composition makes system scintillation-activated photosensitizer for singlet oxygen production. This shows remarkable ability to enhance production in an aqueous environment, under X-ray irradiation, boosting its almost 1 order magnitude. efficiency as coadjutant radiotherapy has been tested vitro,...
The development of hybrid nanoscintillators is hunted for the implementation modern detection technologies, like in high energy physics, homeland security, radioactive gas sensing, and medical imaging, as well established therapies radiation oncology, such X-ray activated photodynamic therapy. Engineering physico-chemical properties nanoparticles (NPs) enables manufacture hybrids which conjugation inorganic/organic components leads to increased multifunctionality performance. However,...
A high efficiency emission with a massive Stokes shift is obtained by fluorescent conjugated acene building blocks arranged in nanocrystals. The two ligands of equal molecular length and connectivity, yet complementary electronic properties, are co-assembled zirconium oxy-hydroxy clusters, generating highly crystalline hetero-MOF nanoparticles fast diffusion singlet excitons the framework, coupled fine matching absorption enables to achieve an ultrafast activation low energy...
The coupling of ZnO-based nanomaterials with organic photosensitizers (PS) is potentially interesting for cancer treatment under X-ray. In these conditions, ZnO nanoparticles (NPs) convert the X-ray into UV-Vis emission, promoting PS excitation and producing reactive oxygen species (ROS). Main advantages in vivo applications are photostability biocompatibility, even if its efficient different (typically porphyrin) still a controversial issue, as both high luminescence yield good overlapping...