Ruchir Paladiya

ORCID: 0000-0003-1628-2842
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Drug-Induced Hepatotoxicity and Protection
  • Microscopic Colitis
  • Eosinophilic Esophagitis
  • Gut microbiota and health
  • Liver Disease and Transplantation
  • Diet and metabolism studies
  • Inflammatory Bowel Disease
  • Gastroesophageal reflux and treatments
  • Diverticular Disease and Complications
  • Colorectal Cancer Treatments and Studies
  • Pancreatitis Pathology and Treatment
  • Colorectal Cancer Screening and Detection
  • Healthcare Systems and Public Health
  • Pediatric Hepatobiliary Diseases and Treatments
  • Diet, Metabolism, and Disease
  • Colorectal Cancer Surgical Treatments
  • Sarcoma Diagnosis and Treatment
  • Gallbladder and Bile Duct Disorders
  • Nutritional Studies and Diet
  • Alcohol Consumption and Health Effects
  • Magnesium in Health and Disease
  • Medical Imaging and Pathology Studies
  • Biosimilars and Bioanalytical Methods
  • Therapeutic Uses of Natural Elements

UConn Health
2023-2025

Connecticut Health Foundation
2023

University of Connecticut
2023

B.J. Medical College
2021

208 Background: The use of total neoadjuvant therapy is now standard care and favored when treating locally advanced rectal cancer but its treatment seldom studied in an underserved population. Methods: A retrospective study was conducted on patients with Stage II III colorectal treated either (TNT) followed by resection or conventional (CT) chemoradiation surgery, without adjuvant afterwards. Patients completed between 2015 2023 at the Hartford Hospital Helen Harry Gray Cancer Center...

10.1200/jco.2025.43.4_suppl.208 article EN Journal of Clinical Oncology 2025-01-27

Background: Metabolic syndrome (MetS) is a complex disorder characterized by cluster of metabolic risk factors. Recent research highlights the gut microbiome’s role in regulation, suggesting that modulation through probiotics, prebiotics, and synbiotics may provide novel approach to managing MetS. This umbrella review aims integrate insights from existing meta-analyses explore how changes microbiota influence key body measurement indicators individuals with Methods: A systematic search...

10.1097/ms9.0000000000003140 article EN Annals of Medicine and Surgery 2025-03-07

Introduction: Type 2 diabetes mellitus can give rise to several complications in the body, including electrolyte imbalance. In this study, we aim find association of hypomagnesemia with duration and severity diabetes. Understanding between magnesium may assist early detection help manage associated

10.7759/cureus.15279 article EN Cureus 2021-05-27

ABSTRACT Background Dementia, a significant cause of disability and dependency among older adults. The growing population the elderly in Philippines is expected to increase prevalence dementia country. Purpose This study aims determine Barangay Bangkal, Makati City. Methods Descriptive cross-sectional community-based was conducted City, aged 60 years above over one month from mid-October mid-November 2019. Data collected with help Mini-Mental State Examination – version (MMSE-P) cognitive...

10.1101/2021.02.11.21251546 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-02-12

Introduction: This study aims to evaluate a structured education intervention in adult primary care (APC) for managing Gastroesophageal Reflux Disease (GERD) and reducing unnecessary long-term Proton Pump Inhibitors (PPIs) use an underserved population. Methods: The spanned from June 2022 - May 2023 involved weekly lectures delivered over 1 month providers. emphasized the importance of GERD symptom reasessment, lifestyle changes, GI referrals, appropriate PPI use. We implemented smart phrase...

10.14309/01.ajg.0000956772.85454.ba article EN The American Journal of Gastroenterology 2023-10-01

Introduction: Biologic drugs have played a key role in the effective induction and maintenance of disease remission ulcerative colitis (UC). With subclasses ranging from anti-tumor necrosis factor agents to anti-integrins anti-IL12/23 therapies, biologics revolutionized pharmacological management UC since early 2000s. These therapies variable safety profiles with several side-effects being reported patients on these medications. In nationwide cohort here, we stratify biologic ustekinumab,...

10.14309/01.ajg.0000953848.50788.0d article EN The American Journal of Gastroenterology 2023-10-01

Introduction: Sarcomas are a rare group of malignant tumors derived from mesenchymal tissues, constituting less than 1% all adult malignancies. Retroperitoneal sarcoma is uncommon, comprising about 13% sarcomas. Here, we present unique case retroperitoneal well-differentiated liposarcoma diagnosed with endoscopic ultrasound (EUS) guided fine needle biopsy (FNB) and how it helped change the management in our patient. Case Description/Methods: A 77-year-old Thai man previous smoking history...

10.14309/01.ajg.0000962984.08886.3b article EN The American Journal of Gastroenterology 2023-10-01

Introduction: Liraglutide is a GLP-1 receptor agonist commonly used for treatment of diabetes mellitus and increasingly weight loss. We present unique case drug-induced liver injury with autoimmune features (AI-DILI) secondary to Liraglutide. AI-DILI characterized by accompanied laboratory evidence autoimmunity induced medication. Key include resolution after the withdrawal offending medication use short-term immunosuppressive therapy, without relapse upon taper. Case Description/Methods: A...

10.14309/01.ajg.0000964472.54085.c4 article EN The American Journal of Gastroenterology 2023-10-01

Hepatic Encephalopathy (HE), a complication of chronic liver disease, presents with neurological and psychiatric symptoms. It has four grades. Minimal (MHE) is the mildest form HE. Over last two decades, many Randomized Controlled Trials (RCTs) have been performed to understand role various treatments in L-Ornithine L-aspartate (LOLA) also studied. stable salt amino acids; L-aspartate. acts help utilize extra ammonia by urea cycle hence lowers levels. This review aims LOLA HE, MHE, as...

10.26502/aimr.0060 article EN Archives of Internal Medicine Research 2021-01-01
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