A5088841662- Polyomavirus and related diseases
- Multiple Sclerosis Research Studies
- Systemic Sclerosis and Related Diseases
- Electrolyte and hormonal disorders
- Peripheral Neuropathies and Disorders
- CNS Lymphoma Diagnosis and Treatment
- Renal function and acid-base balance
- Lymphoma Diagnosis and Treatment
- Cardiac Ischemia and Reperfusion
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
First Pavlov State Medical University of St. Petersburg
2022
Introduction . Infusion therapy, despite all its advantages, is not fully understood regarding impact on the cardiovascular system when large volumes of fluid are used. Objective To assess response to massive infusion load in 5 healthy individuals. Materials and Methods The study included volunteers (2 men 3 women), with a mean age 31.6±5.3 years, weight 73.25±15.8 kg, body surface area 1.83±0.2 m². protocol involved administration 0.9 % sodium chloride solution through peripheral catheter...
Introduction. Multiple sclerosis (MS) is a chronic autoimmune and neurodegenerative disease of the central nervous system (CNS). High-dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation (HDIT–AHSCT) most eff ective method treating MS, which has positive ect on quality life patients inhibition progression disability. The aim study was to analyze dynamics in MS who underwent HDIT– AHSCT groups diff erent clinical effi cacy this method. Material methods....
Introduction. In 2018–2020, a study was conducted in the Russian Federation on efficacy and safety of highdose immunosuppressive therapy with autologous hematopoietic stem cell transplantation (HDIT-AHSCT) multiple sclerosis (MS). The aim to analyze preliminary data effectiveness HDIT-AHSCT patients MS who participated clinical approbation method. Material methods. 21 were included single-center Pavlov University (Saint Petersburg) observational study. 10 (47.6%) Expanded Disability Status...
Introduction. To date, data have been accumulated indicating the high effectiveness of HDIT-AHSCT and possibility preserving improving quality life patients after its application. The objective was to analyze dynamics using standardized assessment tools in with MS for 3 years use HDIT-AHSCT, who participated program clinical approbation method. Methods materials . single-center observational study included 21 (10 women, 11 men) a reliable diagnosis MS, underwent at Pavlov First Saint...
CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) syndrome is a chronic of the pons accumulation contrast agent responding glucocorticosteroid therapy (GCS). This immune- mediated brainstem lesion requires extensive differential diagnosis. The literature provides descriptions delayed response GCS or refractory GCS. Such cases require customized treatment tactics. In clinical case presented by authors, it was possible achieve disease...