- Insect and Pesticide Research
- Plant and animal studies
- Insect and Arachnid Ecology and Behavior
- Nanoplatforms for cancer theranostics
- Neurobiology and Insect Physiology Research
- Cell Image Analysis Techniques
- Glioma Diagnosis and Treatment
University of Würzburg
2020-2023
Universitätsklinikum Würzburg
2017
Abstract Honeybees rely on nectar as their main source of carbohydrates. Sucrose, glucose, and fructose are the components plant nectars. Intriguingly, honeybees express only 3 putative sugar receptors (AmGr1, AmGr2, AmGr3), which is in stark contrast to many other insects vertebrates. The partially characterized. AmGr1 detects different sugars including sucrose glucose. AmGr2 assumed act a co-receptor only, while AmGr3 assumedly receptor. We show that honeybee gustatory receptor highly...
Honeybees (Apis mellifera) need their fine sense of taste to evaluate nectar and pollen sources. Gustatory receptors (Grs) translate signals into electrical responses. In vivo experiments have demonstrated collective responses the whole Gr-set. We here disentangle contributions all three honeybee sugar (AmGr1-3), combining CRISPR/Cas9 mediated genetic knock-out, electrophysiology behaviour. show an expanded spectrum AmGr1 receptor. Mutants lacking a reduced response sucrose glucose but not...
// Simon Memmel 1 , Dmitri Sisario 1, 2 Caren Zöller Vanessa Fiedler Astrid Katzer Robin Heiden Nicholas Becker Lorenz Eing Fábio L.R. Ferreira Heiko Zimmermann 3, 4 Markus Sauer Michael Flentje Vladimir L. Sukhorukov 2, * and Cholpon S. Djuzenova Department of Radiation Oncology, University Hospital Würzburg, Germany Biotechnology Biophysics, 3 Fraunhofer-Institut für Biomedizinische Technik, Sulzbach, Molekulare und Zelluläre Biotechnologie/Nanotechnologie, Universität des Saarlandes,...
Abstract Background Honeybees rely on nectar as their main source of carbohydrates [1]. Sucrose, glucose and fructose are the components plant nectars [2] [3]. Intriguingly, honeybees express only three putative sugar receptors (AmGr1, AmGr2 AmGr3) [4], which is in stark contrast to many other insects vertebrates. The partially characterized [5] [6]. AmGr1 detects different sugars including sucrose glucose. assumed act a co-receptor only, while AmGr3 assumedly receptor. Results We show that...
Abstract Honeybees ( Apis mellifera ) need their fine sense of taste to evaluate nectar and pollen sources. Gustatory receptors (Grs) translate signals into electrical responses. In vivo experiments primarily demonstrate collective responses the whole Gr-set, but little is known about individual impact receptors. Here, we disentangle for first time contributions three gustatory (AmGr1-3) in sugar sensing honeybees by combining CRISPR/Cas9 mediated genetic knock-out, electrophysiology...