A5042261377- Reproductive Physiology in Livestock
- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Pregnancy and preeclampsia studies
- Veterinary Equine Medical Research
- Diverticular Disease and Complications
- Effects of Environmental Stressors on Livestock
- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- Sperm and Testicular Function
- Preterm Birth and Chorioamnionitis
- Animal health and immunology
- Genetic Syndromes and Imprinting
- Circular RNAs in diseases
- Estrogen and related hormone effects
- Birth, Development, and Health
- Epigenetics and DNA Methylation
- Gut microbiota and health
- Pregnancy-related medical research
- Urologic and reproductive health conditions
- Galectins and Cancer Biology
- Kruppel-like factors research
King Abdullah Medical City
2025
University of Kentucky
2018-2024
South Valley University
2024
Mansoura University
2014-2023
Damietta University
2023
Al-Azhar University
2021-2023
Texas A&M University
2021
University of Miyazaki
2011-2020
University of the Witwatersrand
2001
In spite of controversy, recent studies present evidence that a microbiome is in the human placenta. However, there limited information about potential equine placental microbiome. study, we characterized microbial population placenta (chorioallantois) healthy prepartum (280 days gestation, n = 6) and postpartum (immediately after foaling, 351 11) mares, using 16S rDNA sequencing (rDNA-seq). both groups, majority bacteria belonged to phyla Proteobacteria, Firmicutes, Actinobacteria,...
The use of intravenous contrast media (IVCM) in computed tomography (CT) scans enhances image quality by improving detail and accuracy, which is crucial for diagnosing complex medical conditions. While IVCM does provide notable benefits, it also carries the risk rare but potentially life-threatening adverse reactions. aim this study was to evaluate expertise preparedness CT radiographers managing severe reactions IVCM. Furthermore, research seeks examine how variables such as professional...
The current study aimed to define the plasma profile of anti-Müllerian hormone (AMH) and follicle stimulating (FSH) in heifers during postnatal life until achieving puberty, as defined by progesterone (P4) profile, demonstrate a relationship between AMH age puberty onset. Blood samples collected from 11 Japanese Black female calves within 1 week after birth (W 0) then biweekly sixth (WP 6) were assayed for AMH, FSH, P4. classified into two groups based on onset: ≤42 weeks (early group; EP, n...
The aim of the present study was to describe temperature different portions female genital tract and their relation rectal investigate effect steroid hormones profiles on these variables over estrous cycle in cattle. Four nonpregnant Japanese Black cows were investigated daily two successive cycles using a digital thermometer with long probe rounded-end sensor record rectum (RT), vagina (VT), cervix (CT), uterine body (UBT) horns (UHT). Blood samples collected immediately before recording...
The current study aimed to elucidate the mechanisms underlying myometrial activation during equine placentitis related progestogens and progesterone receptor signaling pathways. Placentitis was induced via intracervical inoculation with Streptococcus equi ssp zooepidemicus in mares at approximately 290 days of gestation (placentitis group; n = 6) uninoculated gestationally matched as controls (n 4). Mares control groups were euthanized, samples collected from two regions: region 1-parallel...
The placenta is a dynamic organ which undergoes extensive remodeling throughout pregnancy to support, protect and nourish the developing fetus. Despite importance of placenta, very little known about its gene expression beyond early post-partum. Therefore, we utilized RNA-sequencing characterize transcriptome from fetal (chorioallantois) maternal (endometrium) components mares gestation (4, 6, 10, 11 m). Within endometrium, 47% genes changed pregnancy, while in chorioallantois, 29% underwent...
Abstract Improved understanding of the molecular mechanisms underlying ascending equine placentitis holds potential for development new diagnostic tools and therapies to forestall placentitis-induced preterm labor. The current study characterized placental transcriptome (chorioallantois [CA] endometrium [EN]) during (placentitis group, n = 6) in comparison gestationally-matched controls (control 6). Transcriptome analysis identified 2953 805 differentially expressed genes CA EN placentitis,...
This study was carried out to evaluate the blood profile and tissue expression of Anti-Müllerian hormone (AMH) as a biomarker for granulosa-theca cell tumors (GTCTs) in cattle. Five cases with unilateral ovarian GTCTs (GTCT group) were investigated comparison other groups Japanese Black cows, which had either cystic disease (COD group, n=5), functional corpus luteum on Days 9 11 estrous cycle (Day 0=estrus; CL n=13) or received superovulation treatment (SOT n=13). We used transrectal...
Anti-Müllerian hormone (AMH) and testosterone (T) profiles in blood were investigated before after an hCG stimulation test to assess their sensitivity specificity for the existence of a functional cryptorchid testis Japanese Black calves. The (3,000 IU) was administered on Day 0, peripheral collected Days 0 (just injection), 5 7 intact male calves (Intact; n=19), bilateral castrated (Castrated; n=17), unilateral calves, which abdominal could been extracted (Uni-crypto; n=9). Castration...
Abstract The key event in placentitis-induced preterm labor is myometrial activation with the subsequent initiation of labor. However, molecular mechanisms underlying are not fully understood mares. Therefore, equine transcriptome was characterized during placentitis (290.0 ± 1.52 days GA, n = 5) and prepartum period (330 3) comparison to normal pregnant mares (289.8 2.18 4). Transcriptome analysis identified 596 290 DEGs myometrium period, respectively, 138 common. included eight genes...
Equine chromosome 24 microRNA cluster (C24MC), the ortholog of human C14MC, is a pregnancy-related miRNA cluster. This believed to be implicated in embryonic, fetal, and placental development. The current study aimed characterize expression profile this maternal circulation throughout equine gestation. miRNAs belonging was analyzed serum non-pregnant (diestrus), pregnant (25 d, 45 4 mo, 6 10 mo), postpartum mares. Among examined, 11 were differentially expressed across time-points. Four...
Steroid production varies widely among species, with these differences becoming more pronounced during pregnancy. As a result, each species has its own distinct pattern of steroids, steroidogenic enzymes, receptors, and transporters to support individual physiological requirements. Although the circulating steroid profile is well characterized equine pregnancy, there much yet be explored regarding factors that steroidogenesis signaling. To obtain holistic view steroid-related transcripts, we...
Most autosomal genes in the placenta show a biallelic expression pattern. However, some exhibit allele-specific transcription depending on parental origin of chromosomes which copy gene resides. Parentally expressed are involved reciprocal interaction between maternal and paternal genes, coordinating allocation resources fetus mother. One main challenges studying parental-specific allelic (allele-specific [ASE]) is cellular remnant at fetomaternal interface. Horses (
Postovulatory aging is a major problem that limits the success of many assisted reproductive technologies (ARTs). Oxidative stress leading cause oocyte aging. This study investigated effects lycopene supplementation in vitro maturation (IVM) medium during mouse oocytes on oocytes' morphology and oxidative status. Mouse cumulus-oocyte complexes (COCs) were collected cultured IVM either for 17 h, (freshly matured oocytes), or 48 (in vitro-aged with without lycopene. The rate fragmented...