A5021879982- Advances in Cucurbitaceae Research
- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Bioactive Compounds and Antitumor Agents
- Animal Genetics and Reproduction
- Morinda citrifolia extract uses
- Acute Myeloid Leukemia Research
- Essential Oils and Antimicrobial Activity
- Acute Lymphoblastic Leukemia research
- X-ray Diffraction in Crystallography
- Telomeres, Telomerase, and Senescence
- Hematopoietic Stem Cell Transplantation
- Botanical Research and Applications
- Crystallization and Solubility Studies
- Mesenchymal stem cell research
- Exercise and Physiological Responses
- Metal complexes synthesis and properties
- Protein Hydrolysis and Bioactive Peptides
- Phytochemical Studies and Bioactivities
- T-cell and B-cell Immunology
- Seed and Plant Biochemistry
- Phytochemistry and Biological Activities
- Cardiovascular and exercise physiology
- Infant Nutrition and Health
Universidad Nacional Autónoma de México
2014-2025
Universidad de Zaragoza
2022-2024
Polytechnic University of San Luis Potosí
2022
Universidad Autónoma de la Ciudad de México
2017
Mayo Clinic
2007
Sechium edule (Jacq.) Sw. (Cucurbitaceae) is used in ethnomedicine, but the diversity of varietal groups this species has not often been considered. This important because we previously reported that different variety exhibit activities across tumor cell lines.This study investigates chemical composition and biological extracts obtained from S. var. nigrum spinosum.The leukemia P388 line mononuclear bone marrow cells (MNCBMs) were treated with extract at a concentration ranging 40 to 2370...
Periodontal disease (PD) is one of the main causes tooth loss and related to oxidative stress chronic inflammation. Although different treatments have been proposed in past, vast majority do not regenerate lost tissues. In this sense, use dental pulp mesenchymal stem cells (DPMSCs) seems be an alternative for regeneration periodontal bone tissue. A quasi-experimental study was conducted a sample 22 adults between 55 64 years age with PD, without uncontrolled systemic diseases. Two groups...
To determine the effect of consumption Sechium edule (1.5 g/day) for six months on oxidative stress (OxS) and inflammation markers its association with telomere length (TL) in older adults metabolic syndrome (MetS).The study was conducted a sample 48 adults: placebo (EP) experimental (EG) groups. Lipoperoxides, protein carbonylation, 8-OHdG, total oxidant status (TOS), SOD, GPx, H2O2 inhibition, antioxidant (TAS), inflammatory cytokines (IL6, IL10, TNF-α), TL were measured before...
Cachichín (Oecopetalum mexicanum) is a tree from Sierra de Misantla, Veracruz, Mexico, whose fruit produces seed traditionally consumed raw, boiled, or toasted. This study evaluated the effects of three thermal treatments (boiling, commercial toasting, and controlled toasting) on seed's physicochemical properties, including color, water activity (αw), fatty acid profile, using raw (unprocessed) seeds as reference. Results showed that significantly altered αw, lipid composition. Controlled...
Background/Objectives: Chronic hyperglycemia, characteristic of type 2 diabetes mellitus (DM2), promotes the development complications through oxidative stress. Therefore, it is necessary to strengthen antioxidant defenses diabetic patients, even more so if they are elderly. Sechium edule contains high amounts flavonoids, cucurbitacins, and phenolic acids, which why attributed hypoglycemic properties, our aim was determine effect Schium in older patients. Methods: A quasi-experimental study...
The antiproliferative potential of a crude extract from the chayote hybrid H-837-07-GISeM® and its for apoptosis induction were assessed in leukaemic cell lines normal mouse bone marrow mononuclear cells (BM-MNCs). strongly inhibited proliferation P388, J774, WEHI-3 (with an IC50 below 1.3 μg·mL(-1)), reduced viability, induced apoptotic body production, phosphatidylserine translocation, DNA fragmentation. However, had no effect on BM-MNCs. We postulate that these properties make good...
The Sechium edule Perla Negra cultivar is a recently-obtained biological material whose progenitors are S. var. nigrum minor and amarus silvestrys, the latter of which has been reported to have antiproliferative activity against HeLa P-388 L-929 cancer cell lines. present study aimed determine if methanolic extract fruit had same activity. was phytochemically characterized by thin layer chromatography (TLC) column (CC), identifying terpenes flavonoids. compounds identified via high...
Metabolic syndrome (MetS) is a risk factor for cognitive deterioration and frailty in older adults. In this regard it has been shown that oxidative stress (OxS) chronic inflammation are involved the pathophysiology of these alterations. Harmless antioxidant anti-inflammatory therapeutic alternatives have proposed, such as consumption
Abstract Copper(II) complexes ( 1 – 4 ) of tri‐ or tetradentate bis(2‐methylbenzimidazolyl)amine ligands L have been prepared and characterized by spectroscopic methods in solution, as well the solid state X‐ray crystallography. The act tridentate donors towards cupric ions through one central amine two benzimidazole N atoms state; a water ligand bridging perchlorate group define distorted octahedral environments 2 3 . Complex has square‐pyramidal coordination geometry, with an additional...
Metabolic syndrome (MetS) has a high prevalence in older adults and is risk factor for cardiovascular diseases complications of old age. It also been related to oxidative stress (OxS) chronic inflammation (CI) their consequent alterations. Therefore, it important propose therapeutic alternatives such as the consumption Sechium edule (Chayote), since hypoglycemic, hypotensive, lipogenesis inhibitor properties are attributed it. We carried out study 81 (OA) with MetS determine effect chayote...
In addition to their own antioxidants, human cells feed on external such as the phenolic compounds of fruits and vegetables, which work together keep oxidative stress in check. Sechium edule, an edible species chayote, has with antioxidant activity antineoplastic activity. A hybrid shows one thousand times greater than species, but its anti-inflammatory activities content are unknown. The aim this study was determine capacity extract vitro vivo. Phytochemical analysis using HPLC showed that...
Patients with metabolic syndrome (MetS) have a redox imbalance, due to decay in antioxidant capacity. Oxidative stress (OxS) is considered an important modulator of telomere shortening and telomerase activity. One the fruits that has been associated effect