A5100637309- Graphene and Nanomaterials Applications
- Polymer Surface Interaction Studies
- 3D Printing in Biomedical Research
- Diatoms and Algae Research
- Gas Sensing Nanomaterials and Sensors
- Food Quality and Safety Studies
- Advanced Photocatalysis Techniques
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Concrete and Cement Materials Research
- Bone Tissue Engineering Materials
- Advanced Surface Polishing Techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Surfactants and Colloidal Systems
- Insect and Pesticide Research
- Innovative concrete reinforcement materials
- Micro and Nano Robotics
- Insect and Arachnid Ecology and Behavior
- biodegradable polymer synthesis and properties
- Innovations in Concrete and Construction Materials
- Tropical and Extratropical Cyclones Research
- Pickering emulsions and particle stabilization
- TiO2 Photocatalysis and Solar Cells
- Additive Manufacturing and 3D Printing Technologies
- Electrospun Nanofibers in Biomedical Applications
Hallym University
2022-2024
Hongik University
2024
Cedars-Sinai Medical Center
2023
Hallym University Medical Center
2023
Hanyang University
2020-2023
Anyang University
2023
Korea Advanced Institute of Science and Technology
1999-2022
Korea Institute of Civil Engineering and Building Technology
2012-2021
World Institute of Kimchi
2021
Korea University
2021
Significance Recent studies have identified a helically folded tetramer as the major normal structure of α-synuclein (α-syn) and that resists aggregation. However, underlying mechanisms regulate formation α-syn tetramers remain elusive. Our study shows mutations in glucocerebrosidase 1 ( GBA1 ) depletion-induced deficiency leading to accumulation glycosphingolipids (GSLs) are sufficient cause destabilization increase susceptibility human dopaminergic neurons cytotoxicity due exposure...
Cell-in-shell biohybrid structures, synthesized by encapsulating individual living cells with exogenous materials, have emerged as exciting functional entities for engineered emergent properties outside the scope of biochemical modifications. Artificial exoskeletons have, to date, provided physicochemical shelters inside in first stage technological development, and further advances field demand catalytically empowered, cellular hybrid systems that augment biological functions even introduce...
The ancient wisdom found in iron gall ink guides this work to a simple but advanced solution the molecular engineering of fluidic interfaces. Fe(II)-tannin coordination complex, precursor ink, transforms into interface-active Fe(III)-tannin species, by oxygen molecules, which form self-assembled layer at interface spontaneously still controllably. Kinetic studies show that oxidation rate is directed counteranion Fe(II) salts, and FeCl2 be more effective than FeSO4 -an ingredient ink-in...
<italic>S. cerevisiae</italic>encapsulated with a poly(norepinephrine)/silica double-layered shell showed multiple resistance to enzymatic attack, desiccation, and UV-C irradiation. The biochemical response of the encapsulated yeast may also contribute resistance.
In the area of cell-surface engineering with nanomaterials, metabolic and functional activities encapsulated cells are manipulated controlled by various parameters artificial shells that encase cells, such as stiffness elasticity, thickness, porosity. The mechanical durability physicochemical stability inorganic prove superior to layer-by-layer-based organic regard cytoprotection, but it has been difficult vary including their thickness. this work, we combine layer-by-layer technique a...
Abstract The adsorption of biomolecules onto nanomaterials can alter the performance in vitro and vivo. Recent studies have primarily focused on protein “corona”, formed upon proteins nanoparticles biological fluids, which change fate nanoparticles. Conversely, interactions between other classes namely, lipids, nucleic acids, polysaccharides received less attention despite their important roles biology. A possible reason is challenge associated with investigating biomolecule using current...
The simple use of vitamin C leads to the reductive disassembly Fe<sup>3+</sup>-TA complex and<italic>in situ</italic>artificial shell degradation in single-cell nanoencapsulation.
In the present study, properties of Lactiplantibacillus (Lpb.) plantarum WiKim0112 isolated from kimchi were evaluated by comparing its probiotic to those Lpb. WCFS1 and KACC 11451 different sources. both pH 2 3, media containing pepsin, Wikim0112, showed higher cell viability than KACC11451. Viability all strains in a medium pancreatin bile salt oxgall was significantly decreased compared control. highest thermotolerance, followed Wikim0112 similar level antibacterial activity exhibited an...
Abstract Living cells have the irreplaceable capability to achieve a wide range of complex biochemical reactions precisely and efficiently, which makes them attractive materials for therapeutic applications. In lieu traditional biological approaches primarily focused on augmentation innate functions cells, there has been appreciable progress in development engineered mainly based chemical modifications cell surfaces, at single‐cell level, empowers individual living with designed...
Vascular calcification is an advanced feature of atherosclerosis for which no effective therapy available. To investigate the modulation or reversal calcification, we identified calcifying progenitor cells and investigated their calcifying/decalcifying potentials. Cells from aortas mice were sorted into four groups using Sca-1 PDGFRα markers. Sca-1(+) (Sca-1(+)/PDGFRα(+) Sca-1(+)/PDGFRα(-)) exhibited greater osteoblastic differentiation potentials than Sca-1(-) (Sca-1(-)/PDGFRα(+)...
Although the programmed degradation of biocompatible films finds applications in various fields including biomedical and bionanotechnological areas, coating methods have generally been limited to be substrate-specific, not applicable any kinds substrates. In this paper, we report a dopamine derivative, which allows for both universal substrates stimuli-responsive film degradation, inspired by mussel-adhesive proteins. Two moieties are linked together disulfide bond, cleavage enables...
A novel halophilic archaeon (strain B1(T)) belonging to the genus Natronococcus was isolated from shrimp jeotgal, a traditional fermented food Korea. Colonies of this strain were orange-red and cells non-motile cocci that stained Gram-variable. Strain B1(T) grew in 7.5-30.0 % (w/v) NaCl at 21-50 degrees C pH 7.0-9.5, with optimal growth occurring 23-25 37-45 7.5. most closely related type occultus, which it shared 97.91 16S rRNA gene sequence similarity. Within phylogenetic tree, branching...
One-step assembly of iron(III)–tannic acid (Fe3+–TA) complex forms nanothin (∼10 nm) films on various substrates within minutes. In this deposition scheme, however, the film does not grow continuously over time even though Fe3+–TA is still abundant in coating solution. paper, we report that salt addition dramatically changes one-off characteristic to continuous one, and each has its optimum concentration (CMFT) produces maximum thickness. For detailed investigation effects, employed salts,...
Abstract Cell nanoencapsulation, generating cell‐in‐shell structures (“artificial spores“), provides a chemical toolbox for controlling the cellular behaviors and functional characteristics of individual cells. Among shell materials studied so far, naturally occurring polyphenolic compounds, including polydopamine tannic acid, have intensively been employed in cell‐surface engineering, because their material‐independent coating property eliminates an extra priming step inducing subsequent...
Abstract Inspired by the biogenic magnetism found in certain organisms, such as magnetotactic bacteria, magnetic nanomaterials have been integrated into living cells for bioorthogonal, manipulation of cells. However, magnetized so far reported to be only binary system (on/off) without any control magnetization degree, limiting their applications typically simple accumulation or separation a whole. In this work, degree is tightly controlled, leading generation multiple subgroups cells, and...
Supramolecular self-assembly of Fe3+ and tannic acid (TA) has received great attention in the fields materials science interface engineering because its exceptional surface coating properties. Although advances strategies often suggest that kinetics generation interface-active Fe3+-TA species is deeply involved film formation, there no acceptable elucidation for process. In this work, we developed enzyme-mediated kinetic control Fe2+ oxidation to a Fe2+-TA complex iron-gall-ink-revisited...
Abstract The melanoidin from soluble coffee is utilized as a material‐independent, multipurpose coating material. Instantaneous complexation of the (CM) with ferric ion (Fe 3+ ) leads to surface‐adhesive aggregates, inducing sequential film deposition. Various chemical groups CM also allow for post‐functionalizations film, including surface‐initiated, ring‐opening polymerization and bioinspired silicification. In addition, CM‐based applied single‐cell nanoencapsulation strategy biphasic...
In this investigation, we propose a technique to obtain not only the dimensional profile of an undoped double-side polished silicon (Si) wafer but also its refractive index simultaneously. This is based on low coherence scanning interferometry using near-infrared light around 1 µm wavelength, for which transmission non-zero and detectable by typical visible CCD camera. As experimental results show, profiles optical thicknesses, geometrical group indices phase were successfully obtained...
This paper proposes a robust fingerprint-based authentication algorithm that ensures secure verification even with limited-sized partial fingerprints. It has become increasingly common number of recent consumer devices, such as smartphones, employ fingerprint sensors for user authentication. The to be embedded are generally preferred take up less space better usability and product design, the sensing areas therefore limited in size. To supplement insufficient area, devices often store...