A5113756925- Carcinogens and Genotoxicity Assessment
- Infectious Encephalopathies and Encephalitis
- Cancer Cells and Metastasis
- Neurotransmitter Receptor Influence on Behavior
- Synthesis and bioactivity of alkaloids
- Plant biochemistry and biosynthesis
- Plant Toxicity and Pharmacological Properties
- Biotechnology and Related Fields
- Pharmacological Effects of Natural Compounds
- Microbial Metabolism and Applications
- Acute Lymphoblastic Leukemia research
- Infectious Diseases and Tuberculosis
- Synthesis and Biological Evaluation
- GABA and Rice Research
- Ginger and Zingiberaceae research
- Genetically Modified Organisms Research
- Hematological disorders and diagnostics
- Drug-Induced Hepatotoxicity and Protection
- Psychedelics and Drug Studies
- Forensic Toxicology and Drug Analysis
Universidad Veracruzana
2024
University of Buenos Aires
2000
Universidad de Ciencias Médicas de la Habana
1998
Mevinolin, a fungal metabolite, was isolated from cultures of Aspergillus terreus. The structure and absolute configuration mevinolini its open acid form, mevinolinic acid, were determined by combination physical techniques. Mevinolin shown to be 1,2,6,7,8,8a-hexahydro-beta, delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-1-naphthalene-hepatanoic delta-lactone. in the hydroxy-acid is potent competitive inhibitor 3-hydroxy-3-methylglutaryl-coenzyme A reductase [mevalonate: NADP+...
The cytogenetic effects of aqueous extracts Chenopodium multifidum L. (Paico) were determined by addition the and fractions to human lymphocyte cultures. Toxicity was evaluated analysis chromosomal aberrations (CA), sister chromatid exchange (SCE), mitotic (MI) replication (RI) indexes. results showed an increase in CA frequency cultures exposed infusion decoction, no modification CPK values either decoction or infusion, a decrease MI decoction. These suggested genotoxic “Paico” extracts.
México es un país con una riqueza vegetal importante, ya que concentra alrededor del 10% de todas las especies vegetales existentes en el mundo. La familia Asteraceae amplia y contiene gran variedad metabolitos secundarios, los cuales tienen potencial como nuevos tratamientos para diversa gama enfermedades. Un ejemplo género Verbesina, cual tiene actividad antiinflamatoria, antioxidante, antibacteriana, antifúngica, anticriptocócica, antiacné cicatrizante. Por otro lado, dentro Verbesina se...