A5030796973- Microfluidic and Capillary Electrophoresis Applications
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Advanced Energy Technologies and Civil Engineering Innovations
- Microfluidic and Bio-sensing Technologies
- Crystallography and molecular interactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced biosensing and bioanalysis techniques
- Synthesis and Properties of Aromatic Compounds
- Chemical Synthesis and Analysis
- DNA and Nucleic Acid Chemistry
- Molecular spectroscopy and chirality
- Nanopore and Nanochannel Transport Studies
- Antibiotics Pharmacokinetics and Efficacy
- Advanced Proteomics Techniques and Applications
- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Biosensors and Analytical Detection
- Electrowetting and Microfluidic Technologies
- Monoclonal and Polyclonal Antibodies Research
- Protein purification and stability
- Electrochemical sensors and biosensors
- Biochemical and Molecular Research
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
2016-2025
Czech Academy of Sciences
2010-2024
Bernstein Center for Computational Neuroscience Tübingen
2016-2020
Gilead Sciences (Australia)
2006
Abstract The article gives a comprehensive review on the recent developments in applications of high‐performance capillary electromigration methods, zone electrophoresis, isotachophoresis, isoelectric focusing, affinity electrokinetic chromatography, and electrochromatography, to analysis, preparation, physicochemical characterization peptides. presents new approaches theoretical description experimental verification behavior peptides, covers methodological aspects electroseparations such as...
Abstract The incorporation of phosphorothioate linkages has recently been extensively employed in therapeutic oligonucleotides. For their separation and quality control, new high‐efficient high‐sensitive analytical methods are needed. In this work, a affinity capillary electrophoresis method developed applied for the potential anticancer drug, 2′,3′‐cyclic diadenosine diphosphorothioate ( R p , ) (ADU‐S100), three newly synthesized diastereomers its difluorinated derivative, 3′,3′‐cyclic...
This article gives an overview of the applications capillary electrophoretic methods to investigate non‐covalent interactions peptides (peptide complexes) with variable middle‐ and high‐molecular‐mass receptors (ligands) as well small ions molecules in period 2007–2014. Different modes methods, such mobility shift (vacancy) affinity electrophoresis, multiple injection partial filling Hummel–Dryer method, vacancy peak method (continuous) frontal analysis are briefly described their...
The review provides an overview of recent developments and applications capillary electromigration (CE) methods for the determination important physicochemical parameters various (bio)molecules (bio)particles. These include actual limiting (absolute) ionic mobilities, effective electrophoretic charges, isoelectric points, electrokinetic potentials, hydrodynamic radii, diffusion coefficients, relative molecular masses, acidity (ionization) constants, binding constants stoichiometry...