A5032585205- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Diverticular Disease and Complications
- Autoimmune and Inflammatory Disorders
- Burn Injury Management and Outcomes
- Obstructive Sleep Apnea Research
- Trauma and Emergency Care Studies
- Enhanced Recovery After Surgery
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Esophageal Cancer Research and Treatment
- Mobile Health and mHealth Applications
- Intestinal Malrotation and Obstruction Disorders
- Cardiac Structural Anomalies and Repair
- Injury Epidemiology and Prevention
- Sleep and related disorders
- Traumatic Ocular and Foreign Body Injuries
- Ultrasound in Clinical Applications
- COVID-19 and healthcare impacts
- Heart Failure Treatment and Management
- Diabetes Treatment and Management
- RNA Research and Splicing
- Atrial Fibrillation Management and Outcomes
- RNA modifications and cancer
Massachusetts General Hospital
2022-2025
Harvard University
2022-2025
University of Chicago
2018-2024
Abstract Background Ustekinumab has been recently approved for the treatment of moderately to severely active ulcerative colitis (UC). The registry trials ustekinumab in UC demonstrated efficacy and safety, but data on real-world outcomes are limited. We describe effectiveness safety patients with from 2 US tertiary inflammatory bowel disease centers. Methods Patients treated at NYU Langone Health (New York, New York) University Chicago Medical Center (Chicago, Illinois) between January 2016...
Sodium–glucose cotransporter 2 (SGLT2) inhibitors are underutilized in people with type diabetes after coronary artery bypass grafting (CABG). This study investigated the association of presence an endocrinologist on treatment teams SGLT2 inhibitor prescription patients CABG. The was associated a more than twofold increase odds obtaining prescription. finding suggests that involving endocrinologists these patients’ postoperative care may improve and use
Despite significant differences in surgical outcomes between pediatric and adult patients with ulcerative colitis (UC) undergoing colectomy, counseling on has largely been guided by data from adults. We compared pouch survival who underwent total proctocolectomy ileal pouch-anal anastomosis (IPAA).
Abstract Background Patients with inflammatory bowel disease (IBD) who undergo proctocolectomy ileal pouch–anal anastomosis may develop pouchitis. We previously proposed a novel endoscopic classification of pouchitis describing 7 phenotypes differing outcomes. This study assessed phenotype transitions over time. Methods classified pouch findings into main phenotypes: (1) normal, (2) afferent limb (AL) involvement, (3) inlet (IL) (4) diffuse, (5) focal inflammation the body, (6) cuffitis, and...
Older adults with burn injuries have a high risk of readmission after the initial admission. Frailty is associated poor outcomes from injury, however, it remains unknown if frailty impacts in older index Our study aims to examine patient, frailty, burn, surgical, and hospital factors that contribute 90-day readmissions an acute burn. Patients ≥ 50 years age diagnosis Nationwide Readmissions Database (2016-2018) were included. who died during admissions excluded analysis. Patient, stay,...
Abstract Background The modified pouchitis disease activity index (mPDAI) based on clinical symptoms and endoscopic findings is used to diagnose pouchitis, but validated instruments monitor are still lacking. We recently established an classification that described 7 phenotypes with different outcomes. assessed compared mPDAIs among in inflammatory bowel (IBD). Methods retrospectively reviewed pouchoscopies classified them into main phenotypes: normal (n = 25), afferent limb (AL) involvement...
Abstract Older adults with an acute burn experience a high frequency of in-hospital mortality. However, traditional mortality prediction models are less accurate for older likely because they do not account geriatric specific factors, such as frailty. This study aims to investigate the impact frailty on in adult patients. Patients ≥50 years age diagnosis National Inpatient Sample (2016–2018) were included cohort. Three multivariable logistic regression predict generated and compared. The 1)...
BACKGROUND: Updated goals of management IBD patients include monitoring disease activity, yet compliance with such strategies is poorly studied. We are performing a multi-year study active and quiescent to assess the utility wearable, continuously biosensor validating activity scheduled stool (calprotectin) serum (CRP) testing. This assessed these passive strategies. METHODS: Patients diagnosed were recruited for prospective using (Fitbit Alta HR, San Francisco, CA) mobile application...
BACKGROUND: Understanding the factors that contribute to a prolonged length of stay (LOS) for IBD patients after bowel surgery is essential improving quality care provided these patients. Early ambulation and sleep are important post-operative recovery (1,2). We used activity data collected from wearable biosensor predict LOS undergoing surgery. METHODS: conducted prospective study Patients were Fitbit (Charge or Alta HR, San Francisco, CA) asked download install proprietary smart phone...
INTRODUCTION: Ustekinumab has been recently approved for the treatment of moderately to severely active ulcerative colitis (UC). The registry trials ustekinumab in UC demonstrated efficacy and safety, but data on effectiveness safety real world are limited. We describe patients with from two US tertiary IBD centers. METHODS: Patients treated at NYU Langone Medical Center (New York, NY) University Chicago (Chicago, IL) between January 2016 March 2020 were retrospectively included. primary...
Abstract Background Pouchitis can develop in up to 70% of patients with inflammatory bowel disease (IBD) treated by proctocolectomy ileal pouch-anal anastomosis (IPAA). In our recent work, we proposed the “Chicago classification pouchitis” describing 7 main pouch phenotypes differing outcomes. this study, assessed transition classification. Methods This is a retrospective study IBD IPAA who subsequently underwent pouchoscopies at University Chicago between June 1997 and December 2019. We...
BACKGROUND: In patients with inflammatory bowel disease (IBD), surgical intervention is sometimes required due to medically refractory colitis or the development of neoplasia, and restorative proctocolectomy ileal pouch-anal anastomosis (IPAA) most common procedure for those colitis. However, pouchitis can develop in up 80% after surgery significantly impairs quality life. Despite high prevalence pouchitis, endoscopic phenotypes have not been clarified. This study assessed frequency risk...
INTRODUCTION: In patients with inflammatory bowel disease (IBD), restorative proctocolectomy ileal pouch-anal anastomosis (IPAA) is sometimes required due to medically refractory colitis or neoplasia. However, persistent inflammation in a strip of rectal cuff (cuffitis) and pouchitis frequently develop after the surgery. Our previously reported cross-sectional study identified that cuffitis might be risk for development. This aimed understand transition J pouch phenotype cuffitis. METHODS:...
BACKGROUND: In patients with inflammatory bowel disease (IBD), surgical intervention is sometimes required due to medically refractory colitis or the development of neoplasia, and restorative proctocolectomy ileal pouch-anal anastomosis (IPAA) most common procedure for those colitis. However, despite a preoperative diagnosis ulcerative (UC), phenotype J pouch which has features similar Crohn’s (CD) may develop after surgery. This study aims assess frequency risk factors fistula in IBD pouch....