A5068644587- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Ovarian function and disorders
- Reproductive System and Pregnancy
- Prenatal Screening and Diagnostics
- Hormonal and reproductive studies
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Pluripotent Stem Cells Research
- Reproductive biology and impacts on aquatic species
- Renal and related cancers
- Reproductive Physiology in Livestock
- Reproductive Health and Technologies
- Animal Genetics and Reproduction
- Testicular diseases and treatments
- Birth, Development, and Health
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Male Reproductive Health Studies
- Sexual function and dysfunction studies
- Ectopic Pregnancy Diagnosis and Management
- Ethics and Legal Issues in Pediatric Healthcare
- Apelin-related biomedical research
- Hypothalamic control of reproductive hormones
- Receptor Mechanisms and Signaling
- Aquaculture Nutrition and Growth
University of South Carolina
2015-2025
Greenville College
2018
Prisma Health
2014-2017
University Medical Center
2014
Charleston Southern University
2010-2012
Beckman Coulter Foundation
2008-2010
Main Line Fertility
2010
Reproductive Biology Associates
2001-2009
University of Miami
2004
Lehigh Valley Hospital Muhlenberg
2004
Body mass index (BMI) has been demonstrated to affect female fertility; however, little information is available on the impact of BMI male fertility or semen parameters. Therefore, study objective was determine relationship between and parameters, including sperm chromatin integrity. We analyzed data samples from 520 men who were grouped based upon calculated values (normal, 20-24 kg/m(2); overweight, 25-30 obese, >30 kg/m(2)). The collected included patient height weight, volume,...
The primary function of the female ovary is production a mature and viable oocyte capable fertilization subsequent embryo development implantation. At birth, contains finite number oocytes available for folliculogenesis. This termed "the ovarian reserve". determination reserve important in assessment treatment infertility. As ages, will decline. Infertility affects approximately 15%-20% reproductive aged couples. most commonly used biomarker assay to assess measurement follicle stimulating...
Alpha-fetoprotein (AFP) is measured during pregnancy in maternal serum to screen for, and amniotic fluid test neural tube defects. This study aimed determine whether or not AFP expressed blastocoel fluid-conditioned media (BFCM) at the blastocyst stage of embryonic development. For this vitro study, BFCM was obtained from embryos following standard embryology laboratory processes. Good quality blastocysts (n=40) had trophectoderm biopsy for preimplantation genetic testing aneuploidy (PGT-A)...
Alpha-fetoprotein (AFP) is measured during pregnancy in maternal serum to screen for, and amniotic fluid test neural tube defects. This study aimed determine whether or not AFP expressed blastocoel fluid-conditioned media (BFCM) at the blastocyst stage of embryonic development. For this vitro study, BFCM was obtained from embryos following standard embryology laboratory processes. Good quality blastocysts (n = 40) had trophectoderm biopsy for preimplantation genetic testing aneuploidy...
Abstract Purpose This retrospective study measured global gene abundance using RNASeq of blastocoel fluid-conditioned media from euploid ICSI-generated embryos to identify genes and signaling pathways associated with maternal age. Methods Blastocoel was obtained following trophectoderm biopsy day-5 blastocysts. Media for were 24 blastocysts (9 patients aged 35 or older). Transcriptome analysis identified differentially expressed when comparing advanced age those younger than 35. Further on...
BACKGROUND: A definitive need exists to identify a biomarker of embryonic viability. Platelet-activating factor (PAF) production by human embryos is related pregnancy potential. METHODS: Conditioned embryo culture media were obtained following conventional IVF on day 3, with PAF levels and outcomes correlated. RESULTS: Overall rate was 68% (17/25) mean 84.1 (± 8.5) pmol/l/embryo level. ranged from 216.4 (pregnant) 3.7 (not pregnant). There significant difference (P < 0.05) in content between...
Platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine; PAF), a potent signaling phospholipid, has significant role in preimplantation embryo development. CFW mouse embryos respond to PAF with improved development and implantation rates. PAF's signal transduction mechanism other cell types is receptor mediated. However, embryonic mRNA for the not been detected. The study objectives were determine presence of two-cell by reverse transcription (RT)-polymerase chain reaction...