- Cardiovascular Effects of Exercise
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Kawasaki Disease and Coronary Complications
- Sports injuries and prevention
- COVID-19 Clinical Research Studies
- Cardiac Imaging and Diagnostics
- Viral Infections and Immunology Research
- Cardiac Arrest and Resuscitation
- Cardiovascular Syncope and Autonomic Disorders
- Chronic Lymphocytic Leukemia Research
- Cardiac Structural Anomalies and Repair
- Cardiac Health and Mental Health
- Congenital heart defects research
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Neurogenetic and Muscular Disorders Research
- Coronary Artery Anomalies
- Pericarditis and Cardiac Tamponade
- Long-Term Effects of COVID-19
Federal Almazov North-West Medical Research Centre
2018-2024
The Turner Scientific Research Institute for Children's Orthopedics
2022-2023
Ministry of Health of the Russian Federation
2022-2023
GOUZ YaO "Solovyov NV Clinical Emergency Hospital"
2023
Aim: to study the clinical characteristics and genetic spectrum of children with arrhythmogenic cardiomyopathy (ACM) who have undergone heart transplantation (HT) or are currently on waiting list (HTWL) Materials Methods: this included 5 pediatric patients 3 female (60%) diagnosed ACM had either HT were HTWL. The mean age cohort was 16 [7,5; 16]. Comprehensive assessments performed for all participants, including evaluation complaints (palpitations, syncope, symptoms failure (HF)), family...
The question of COVID-19 and long-COVID-19 course in children remains unsolved. This infection children, which is associated with COVID-19, can vary from asymptomatic to systemic damage various systems. Multisystem inflammatory syndrome SARS-CoV-2 (MIS-C), a serious condition adolescents after experiencing COVID-19. Published data on MIS-C have indicated that the inflammation be registered gastrointestinal tract (60-100%), as well cardiovascular (80%), nervous (29-58%), respiratory (21-65%)...
Introduction The present study aimed to describe the phenotypic features and genetic spectrum of arrhythmogenic cardiomyopathy (ACM) presented in childhood test validity different diagnostic approaches using Task Force Criteria 2010 (TFC) recently proposed Padua criteria. Patients methods Thirteen patients (mean age at diagnosis 13.6 ± 3.7 years) were enrolled “definite” or “borderline” criteria ACM according TFC <18 years old. Clinical data, including family history, 12-lead...
Arrhythmogenic cardiomyopathy (ACM) is a genetically determined disease with high risk of sudden cardiac death (SCD). The spectrum genetic causes this quite wide and includes mutations in both desmosomal non-desmosomal genes. A positive result examination used as diagnostic tool patients ACM, so its correct interpretation one the key factors personalized approach to managing patient pathology. review presents generalized modern ideas about nature ACM.
Danon’s disease (DD) is a rare multisystem caused by pathogenic variants in the LAMP2 gene. Men are characterized multisystemic Involvement, most often represented triad of symptoms: skeletal myopathy, cardiomyopathy (hypertrophic phenotype), and cognitive dysfunction. Women more likely to have isolated heart disease. Given that women less extracardiac manifestations, diagnosis females can be very difficult untimely. In this article, we present 2 clinical cases BD adolescent girls, an early...
Aim. To identify factors associated with the effectiveness of radiofrequency catheter ablation (RFA) focal atrial tachycardia (AT) in school-aged patients long-term period. Methods. The study group consisted 57 children aged 11 to 17 years months (Me 15.83, IQR 14.63-17.0), who underwent ablation, including repeated, for AT Almazov National Medical Research Centre from December 2009 until April 2023. We analyzed clinical and demographic data, laboratory parameters tachyarrhythmia,...
Over the past 40 years, understanding of arrhythmogenic cardiomyopathy (ACM) has changed significantly. Thus, with advent new knowledge, different terms have been used to name this heart disease: right ventricular dysplasia (ARVD), arrhythmogenic (ARVC), and cardiomyopathy/dysplasia (ARVC/ARVD). In 1995, disease was included in World Health Organization classification cardiomyopathies under ARVC. With discovery left variant, term ACM introduced. The review presents generalized historical...
Background. Hypertrophic cardiomyopathy (HCM) is one of the most common form in children, with an estimated annual incidence 2.9 per 100,000 children. The management patients HCM requires high healthcare costs. Registry-based medical research important tool assessing health care decision making. Objective. To analyze costs state for pediatric based on data patient registry. Materials and methods. study was performed basis Department Pediatric Cardiology Medical Rehabilitation Almazov...
ФедерацияАлексеева Дарья Юрьевна, врач-кардиолог лечебно-консультативного отделения, науч
Objective: to evaluate the data of cardiac screening identify pathology and determine sports participation among in athletes Youth Sports Schools five districts St. Petersburg. Materials methods: 9847 young (average age 13.8 ± 4.9 years, 6127 men) were included study during 8 months. Clinical protocol uncluded collection complaints, anamnesis, family physical examination, ECG 12 leads. If necessary, Holter monitoring, echocardiography, an exercise test performed. Results: typical changes...
Background. The problem of managing children with hypertrophic cardiomyopathy (HCM) remains relevant due to the high risk sudden cardiac death (SCD). Registers patients HCM contribute a better understanding course disease and its outcomes. Objective. To study structure CMP phenotype, as well identify clinical, molecular genetic features outcome in based on anamnestic, clinical instrumental data from an electronic database. Design method / Currently, database includes complete information 80...
Early diagnosis of cardiovascular diseases in people involved sports, and dynamic monitoring them are important for the primary prevention sudden cardiac death. Our study presents clinical instrumental information about health status young athletes with various abnormalities. Continued long-term prospective follow-up underage will contribute to adoption optimal decisions individual assessment athlete’s condition, aimed mainly at protecting a athlete, as well developing his sports career.
The article presents a rare case of combination Ebstein’s anomaly and primary cardiomyopathy in 14-year-old teenager. clinical demonstrates diagnostic difficulties due to an unusual picture, as well interpretation choice treatment tactics.
This article describes a rare clinical manifestation of arrhythmogenic cardiomyopathy in 13-year-old boy - the “hot phase”, characterized by severe chest pain and significant increase on level troponin I. The case demonstrates difficulties differential diagnosis this disease an importance integrated approach to examination patient, including cardiac magnetic resonance imaging genetic testing.
The aim of the study was to evaluate contribution psychoemotional factor in arrhythmogenesis patients with idiopathic ventricular arrhythmias (VA) on basis analysis results various mental stress-tests (MT). Material and methods. 66 VA anxiety neurotic disorders (AND) were included after careful examination. MT performed all according protocol. Results. According data statistical there not stasistically significant differences baseline levels hemodynamic parameters perid rest between MT....
Aim. To develop a protocol for diagnosing exercise-induced arrhythmias and conduction disturbances in children aged 3-6 years without structural heart disease. Material methods . The study included 20 patients (11 boys) 58,7±2,12 months with ventricular (VA) and/or atrioventricular (AV) block according to single electrocardiographic (ECG) records 24-hour ECG monitoring. All underwent thorough clinical paraclinical examination, including exercise stress testing using original Bruce protocols....