A5100740432- Nanoparticle-Based Drug Delivery
- MicroRNA in disease regulation
- Advanced Drug Delivery Systems
- SARS-CoV-2 and COVID-19 Research
- Microstructure and mechanical properties
- COVID-19 Clinical Research Studies
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Circular RNAs in diseases
- vaccines and immunoinformatics approaches
- Nanoparticles: synthesis and applications
- RNA Interference and Gene Delivery
- Advanced Nanomaterials in Catalysis
- Curcumin's Biomedical Applications
- Receptor Mechanisms and Signaling
- Gold and Silver Nanoparticles Synthesis and Applications
- Lanthanide and Transition Metal Complexes
- Computational Drug Discovery Methods
- Metal and Thin Film Mechanics
- Animal Diversity and Health Studies
- Advancements in Transdermal Drug Delivery
- Protein Kinase Regulation and GTPase Signaling
- Machine Learning in Bioinformatics
- Drug Solubulity and Delivery Systems
- Cancer-related molecular mechanisms research
Kangwon National University
2018-2025
Panjab University
2020-2024
Chuncheon Sacred Heart Hospital
2013-2024
Hallym University
2014-2024
Western University of Health Sciences
2019-2024
University College London
2012-2024
Kumaun University
2024
Central University of Punjab
2024
Sam Higginbottom Institute of Agriculture
2024
Great Ormond Street Hospital
2023-2024
Abstract Recently, a novel coronavirus (SARS‐COV‐2) emerged which is responsible for the recent outbreak in Wuhan, China. Genetically, it closely related to SARS‐CoV and MERS‐CoV. The situation getting worse worse, therefore, there an urgent need designing suitable peptide vaccine component against SARS‐COV‐2. Here, we characterized spike glycoprotein obtain immunogenic epitopes. Next, chose 13 Major Histocompatibility Complex‐(MHC) I 3 MHC‐II epitopes, having antigenic properties. These...
Biomolecule-mediated nanoparticle synthesis has recently gained the attention of researchers due to its ecofriendly and non-toxic nature. Metabolites from plant extracts represent a better alternative chemical methods fulfill growing demand for non-hazardous routes. Selenium nanoparticles have an extensive range applications. Thus, biofabrication selenium can be potentially useful in various fields. This study reports green approach biosynthesize (Se-np) using dried Vitis vinifera (raisin)...
Quercetin, a plant-derived flavonoid found in fruits, vegetables and tea, has been known to possess bioactive properties such as anti-oxidant, anti-inflammatory anti-cancer. In this study, anti-cancer effect of quercetin its underlying mechanisms triple-negative breast cancer cells was investigated. MTT assay showed that reduced cell viability time dose dependent manner. For this, not only increased apoptosis but also inhibited cycle progression. Moreover, FasL mRNA expression p51, p21...
To effectively modulate the gene expression within an infected mammalian cell, pathogen Mycobacterium tuberculosis would need to bring about epigenetic modifications at appropriate genomic loci. Working on this hypothesis, we show in study that mycobacterial protein Rv2966c is a 5-methylcytosine-specific DNA methyltransferase secreted out from mycobacterium and gets localized nucleus addition cytoplasm inside host cell. Importantly, binds specific sequences, methylates cytosines...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel (CoV), has recently emerged as significant pathogen for humans and the cause recent outbreak of 2019 disease (COVID-19) throughout globe. For developing any preventive measure, an understanding zoonotic pattern this virus is necessity. We should have clear knowledge its reservoir host, distribution spreading routes. Information about reservoirs transmission among them can help to understand COVID-19 outbreaks. In article,...
COVID-19 leads to mortality of several patients and the cytokine storm is reportedly critical in patients. To reduce storm, we would like propose interleukin (IL) 6 receptor (IL-6R) antagonist therapy for Two humanized monoclonal antibodies are clinical trial following IL-6R therapies namely tocilizumab sarilumab. However, researchers physicians should look more antagonists syndrome severe acute respiratory coronavirus 2 infected persons enhance therapeutic options storm.