- Bone Tissue Engineering Materials
- Advanced Photocatalysis Techniques
- Laser-Ablation Synthesis of Nanoparticles
- TiO2 Photocatalysis and Solar Cells
- Dental Implant Techniques and Outcomes
- Catalytic Processes in Materials Science
- Facial Trauma and Fracture Management
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Dental materials and restorations
- biodegradable polymer synthesis and properties
- Nanoparticles: synthesis and applications
- Gas Sensing Nanomaterials and Sensors
- Transition Metal Oxide Nanomaterials
- Advanced Nanomaterials in Catalysis
- Luminescence Properties of Advanced Materials
- Copper-based nanomaterials and applications
- Wound Healing and Treatments
- Graphene research and applications
- Flame retardant materials and properties
- Hydrogels: synthesis, properties, applications
- Natural Fiber Reinforced Composites
- Photoreceptor and optogenetics research
- Carbon and Quantum Dots Applications
- Research in Cotton Cultivation
Babeș-Bolyai University
2016-2025
Applied Natural Sciences
2023
University of Szeged
2020-2022
Interface (United States)
2021
Spitalul Clinic Județean de Urgență Cluj-Napoca
2016-2021
The bioactive glasses can lead to the promotion of growth granulation tissue, while gold nanoparticles (AuNPs) induce acceleration wound healing including tissue regeneration, connective formation, and angiogenesis. aim this study was evaluate impact using glass (BG) BG-AuNPs composites on skin in experimental rat models for 14 days. Sol-gel derived BGs mixed with Vaseline at 6, 12 18 wt% were used repair response skin. During process healing, granulomatous reaction observed treated...
Nano- and micro-sized ZnO spheres were fabricated via a simple solvothermal synthesis using two different precursors, while diethanolamine was used to control the morphology. The applied solvent composition, precursor ratio treatment temperature mathematically correlated with diameter of spheres. crystallite size could be easily controlled by adjusting temperature, providing flexibility during synthesis. photocatalytic activity its dependence on unique morphology investigated decomposition...
In the present study, polysaccharide-based cryogels demonstrate their potential to mimic a synthetic extracellular matrix. Alginate-based cryogel composites with different gum arabic ratios were synthesized by an external ionic cross-linking protocol, and interaction between anionic polysaccharides was investigated. The structural features provided FT-IR, Raman, MAS NMR spectra analysis indicated that chelation mechanism is main process linking two biopolymers. addition, SEM investigations...
The efficiency of 60SiO<sub>2</sub>·(32 −<italic>x</italic>) CaO·8P<sub>2</sub>O<sub>5</sub>·<italic>x</italic>CuO (mol%) glass-ceramics were proved, and was determined the most appropriate composition for further<italic>in vivo</italic>trials.
The most important concept behind using bone scaffolds is the biocompatibility of material to avoid a local inflammatory response and must have following properties: osteoinduction, osteoconductivity, angiogenesis, mechanical support for cell growth. Gold nanoparticles/gold silver nanoparticles -containing bioactive glasses in biopolymer composites been used enhance regeneration. These were testedin vitroon fibroblast osteoblast lines MTT tests, immunofluorescence, scanning electron...
Rosmarinic acid is a well-known natural antioxidant and anti-inflammatory compound, it one of the polyphenolic compounds found in comfrey plants. Comfrey root also contains allantoin, which helps with new skin regeneration. This study aimed to investigate healing regeneration process wounds Wistar rats using creams based on extract correlate results active extract. The obtained showed that rich bioactive compounds, including salvianolic acid, rosmarinic are known for their great free radical...
The UV-B component of sunlight damages the DNA in skin cells, which can lead to cancer and premature aging. Therefore, it is necessary use creams that also contain UV-active substances. Many sunscreens titanium dioxide due its capacity absorb wavelengths. In present study, titan was introduced alginate chitosan–alginate hydrogel composites are often involved as scaffold compositions tissue engineering applications. Alginate chitosan were chosen their important role regeneration protection....
In the present study, scaffold composites based on alginate-pullulan-bioactive glass‑gold nanoparticles were orthotopically implanted in an experimental model of delayed bone union, rats, given by a metabolic pathology, namely osteoporosis. Differences between treated and untreated groups observed efficacy our biomaterial was evaluated applying micro-CT imaging, together with histological evaluation osteoporotic animals sub-critical defects, at 30 60 days. Osteoporosis successfully induced...
The formation of a calcium phosphate layer on the surface SiO2 -CaO-P2 O5 glasses after immersion in simulated body fluid (SBF) generally demonstrates bioactivity these materials. Grafting by chemical bonding can minimize structural changes protein adsorbed surface. Therefore, this study our interest was to evaluate and blood biocompatibility their modification functionalization with aminopropyl-triethoxysilane and/or fibrinogen. It is shown that fibrinogen glass surfaces induces growing...
New photoluminescent carbon dots with intriguing properties were prepared from carboxylated nanoparticles <italic>via</italic> covalent bonding of <italic>p</italic>-phenylenediamine oligomers.
There is still a lack of available techniques to follow noninvasively the intracellular processes as well track or disentangle various signals from therapeutic agents at site action in target cells. We present here assessment kinetics doxorubicin (DOX) and gold nanoparticle (AuNP) carriers by mapping simultaneously fluorescence photoluminescence lifetime imaging microscopy under two-photon excitation (TPE-FLIM). The new nano–chemotherapeutic system AuNPs@gelatin–hyd–DOX has been fabricated...
The study reports a low cost and scalable pathway for preparing free-standing GO membranes by self-assembly process under ambient conditions at an air–liquid interface of isopycnic sorted water–ethanol fraction.
Bioactive glasses doped with silver are aimed to minimize the risk of microbial contamination; therefore, influence on bioactive properties is intensely investigated. However, information related role played by silver, when added glass composition, biocompatibility scarce. This aspect essential as long content can blood protein adsorption onto surface glass, thus affecting material's biocompatibility. Therefore, from perspective standpoint, finding an optimal in a extremely important issue....
Composites based on sodium alginate, pullulan, and bioactive SiO2-CaO-P2O5 glass-ceramics with copper oxide were prepared as capsules. The obtained samples structurally characterized by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), their bioactivity biocompatibility properties also tested both in vitro vivo XRD, FT-IR, SEM, high-resolution transmission microscopy. fibroblast osteoblast cell viability assays have shown good...
Abstract In the present study, scaffolds based on alginate‐pullulan‐bioactive glass‐ceramic with 0.5 and 1.5 mol % copper oxide were orthotopically implanted in experimental rat models to assess their ability heal an induced bone defect. By implying magnetic resonance imaging scans together histological evaluation of processed samples, a progressive healing was observed within 5 weeks. Furthermore, as regenerative process continued, new tissue formed, enhancing growth irregular spicules...
Understanding graphene oxide's stability (or lack thereof) in liquid solvents is critical for fine-tuning the material's characteristics and its potential involvement future applications. In this work, through use of structural surface investigations, alteration edge-surface properties 2D oxide nanosheets was monitored over a period eight weeks by involving DLS, zeta potential, XRD, XPS, Raman FT-IR spectroscopy techniques. The samples were synthesized as an aqueous suspension original...