A5049557796- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Orthopaedic implants and arthroplasty
- Musculoskeletal pain and rehabilitation
- Medical Imaging and Analysis
- Scoliosis diagnosis and treatment
- Veterinary Orthopedics and Neurology
- Cervical and Thoracic Myelopathy
- Trauma Management and Diagnosis
- Shoulder Injury and Treatment
- Surgical site infection prevention
- AI in cancer detection
- Pleural and Pulmonary Diseases
- Geotechnical and Geomechanical Engineering
- Bone Tissue Engineering Materials
- Tunneling and Rock Mechanics
- Pelvic and Acetabular Injuries
- Automotive and Human Injury Biomechanics
- Advanced Image Processing Techniques
- Generative Adversarial Networks and Image Synthesis
Universität Ulm
2011
A large number of interbody fusion cages are made polyetheretherketone (PEEK). To improve bone on-growth, some coated with a thin layer titanium. This coating may fail when subjected to shear loading.The purpose this testing was investigate whether impaction titanium-coated PEEK into the disc space can result in wear or delamination coating, and titanium subtractive surface etching (no coating) less susceptible such failure.A biomechanical study carried out simulate process clinical practice...
Objectives Although magnetic resonance imaging–based formalized grading schemes for intervertebral disc degeneration offer improved reproducibility compared with purely subjective ratings, their intrarater and interrater reliability are not nearly good enough to be able detect small medium effects in clinical longitudinal studies. The aim of this study thus was develop a method that enables automatic therefore reproducible reliable evaluation based on conventional image data Pfirrmann's...
Abstract Purpose The cause of disc herniation is not well understood yet. It assumed that heavy lifting and extreme postures can small injuries starting either in the inner anulus or from outside close to endplate. Such are accumulated over years until its structure weakened finally a single loading event leads sudden failure last few intact lamellae. This paper describes novel, custom-developed dynamic 6-DOF disc-loading simulator allows complex provoke such damage herniations. Methods...
Intervertebral disc degeneration is frequent in dogs and can be associated with symptoms functional impairments. The degree of assessed on T2-weighted MRI scans using the Pfirrmann classification scheme, which was developed for human spine. However, it could also used to quantify effectiveness regeneration therapies. We tested a deep learning tool able automatically score dog spines, starting from an existing model designed process images patients. midsagittal 5991 lumbar discs patients were...
Spinal flexibility can vary among spinal sections and single motion segments. The purpose of this work was to provide a comprehensive overview the range (RoM) neutral zone (NZ) values all levels collected during 30 years in vitro experiments under standardized testing conditions. RoM NZ data obtained from intact human mono- polysegmental specimens with pure moments 2.5 Nm for cervical, 5 thoracic, 7.5 lumbar spine were collated internal database authors' institution. Descriptive statistics...
In silico trials recently emerged as a disruptive technology, which may reduce the costs related to development and marketing approval of novel medical technologies, well shortening their time-to-market. these trials, virtual patients are recruited from large database response therapy, such implantation device, is simulated by means numerical models. this work, we propose use generative adversarial networks produce synthetic radiological images be used in trials. The models produced credible...
Biomechanical volunteer study.To quantify the stabilizing effect of 2 different semirigid thoracolumbar orthoses during various body movements.Various spinal diseases need to be treated by immobilization. The literature shows, that immobilizing strongly depends on orthosis design and loading direction. Few data are available for directions other than flexion extension.Ten young healthy volunteers (22-44 yr, 5 male, female) performed 4 tasks: full active flexion/extension, lateral bending,...
In order to improve osseointegration, polyetheretherketone (PEEK) interbody fusion cages are frequently surface coated. The bonding strength of the coatings is mostly investigated under unrealistic loading conditions. To close this gap, in study, uncoated and coated were loaded a clinical setup investigate their real resistance against abrasion. Six uncoated, six calcium phosphate (CaP) nanocoated, titanium (Ti) nanocoated PEEK tested study. experimental was designed mimic cage impaction...
The upright posture of the kangaroo suggests that spine could be a possible substitute model for biomechanical studies human spine. A prerequisite this should agreement anatomy in humans and kangaroos. purpose study was to investigate anatomical parameters from C4 S4 compare them with existing data Eight complete spines red giant were obtained 21 measured vertebral bodies, spinal canal, endplate, pedicles, intervertebral discs, transverse, spinous processes. Most similarities between found...
Many recent studies have focused on the functional and clinical importance of cervical lordosis. However, there is little accurate knowledge anatomical parameters that constitute lordosis (i.e., sagittal wedging angles intervertebral discs vertebral bodies) their associations with age sex. Standing lateral radiographs 1020 subjects (424 males, 596 females) a mean 36.6 ± 17.0 years (range 7-95 years) were evaluated retrospectively. Cervical lordosis, sum disc from C2/C3 to C6/C7 body C3 C7...
Background Anterior cage migration in anterior lumbar interbody fusion is a serious complication. To address this risk, designs are now available with integrated screw or blade fixation specially designed surface geometries large teeth ridges. However, the implantation technique itself has not yet been addressed as potential risk factor for migration. This study aimed to investigate whether that implantable without gouging vertebral endplates improved resistance Methodology A novel...
There are various cervical disc prostheses on the market today. They can be subdivided into implants with a ball-and-socket design and flexible core, which is captured between implant endplates sealed using sheaths. Implants an articulating surface mostly metal-on-metal or metal-on-UHMWPE designs and, thus, do not allow for axial damping. The aim of this study to provide mechanical safety performance data MOVE-C prosthesis combines both core.MOVE-C consists cranial caudal metal plate made...
Abstract Purpose The aim of this study was to assess the validity and objectivity a new quantitative radiographic grading system for thoracic intervertebral disc degeneration. Methods involves measurement variables “Height loss” “Osteophyte formation”, which are determined from lateral radiographs, resulting in “Overall degree degeneration” on four-point scale 0 (no degeneration) 3 (severe degeneration). Validation performed by comparing degrees degeneration 54 human discs respective...