A5101666776- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Ultrasound and Hyperthermia Applications
- Pain Management and Opioid Use
- Human Mobility and Location-Based Analysis
- Financial Risk and Volatility Modeling
- Complex Systems and Time Series Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Machine Learning in Healthcare
- Foot and Ankle Surgery
- Nutritional Studies and Diet
- Ultrasound in Clinical Applications
- Nausea and vomiting management
- Context-Aware Activity Recognition Systems
- Hernia repair and management
- Anesthesia and Neurotoxicity Research
- Genetic Associations and Epidemiology
- Spine and Intervertebral Disc Pathology
- Osteoarthritis Treatment and Mechanisms
- Stock Market Forecasting Methods
- Pain Mechanisms and Treatments
- Abdominal Surgery and Complications
- Veterinary Equine Medical Research
- Bone fractures and treatments
- Bioinformatics and Genomic Networks
North Carolina State University
2016-2021
Cleveland Clinic
2014-2017
Istanbul University
2016
Outcomes Research Consortium
2014
Whether to treat metatarsal fractures conservatively or surgically is controversial. We test a hypothesis that treated with non-invasive low-intensity pulsed ultrasound (LIPUS) obtain heal rates comparable current surgical techniques.This retrospective observational cohort study, using patient outcomes from prospectively-collected LIPUS registry required by the U.S. Food & Drug Administration. Registry data were collected over 5-year period and reviewed validated registered nurse. Data for...
Dexmedetomidine constricts cerebral blood vessels without a concomitant reduction in metabolic oxygen consumption. Its safety as sedative patients with neurological diseases thus remains uncertain.Our primary objective was to test the hypothesis that dexmedetomidine is noninferior propofol regards flow (CBF) velocity and brain oxygenation.Unblinded randomised trial.Cleveland Clinic Hospital, Cleveland, from November 2010 July 2013.Forty-four scheduled for insertion of deep-brain stimulating...
Objective: The clinical value of low-intensity pulsed ultrasound (LIPUS) for fresh fracture is known. Yet, in the absence a definition what “fresh” is, payers have adopted study inclusion criteria drawn from randomized trials as de facto definitions which patients should be treated, with defined <1 week old. Patients may thus ineligible LIPUS treatment after 1, potentially denies access to who could benefit LIPUS. We seek characterize inflection point at heal rate declines. Design:...
Observational longitudinal studies are a common means to study treatment efficacy and safety in chronic mental illness. In many such studies, changes may be initiated by either the patient or their clinician can thus vary widely across patients timing, number, type. Indeed, observational pathway of STEP-BD bipolar depression, one motivations for this work, no two have same history even after coarsening clinic visits weekly time-scale. Estimation an optimal regime using data is challenging as...
Abstract Osteoarthritis (OA) is a chronic condition often associated with pain, affecting approximately fourteen percent of the population, and increasing in prevalence. A globally aging population have made treating OA-associated pain as well maintaining mobility activity public health priority. OA affects all mammals, use spontaneous animal models one promising approach for improving translational research development effective treatment strategies. Accelerometers are common tool...
A regularized vector autoregressive hidden semi-Markov model is developed to analyze multivariate financial time series with switching data generating regimes. Furthermore, an augmented EM algorithm proposed for parameter estimation by embedding estimators the state-dependent covariance matrices and autoregression in M-step. The performance of evaluated both simulation experiments on New York Stock Exchange portfolio data.
(Int J Obstet Anesth. 2015;24(1):35–40) There is an association between pregnancy and increased intrathecal local anesthetic spread (and thus, lower requirements), although the exact mechanisms behind this are unknown. 2 potential anatomic explanations: (1) in supine position, pregnant uterus compresses inferior vena cava (IVC), diverting blood into vertebral venous system displacing lumbosacral cerebrospinal fluid (CSF) a cranial direction; or (2) addition to direct compression of IVC,...