- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- SARS-CoV-2 detection and testing
- COVID-19 diagnosis using AI
- COVID-19 and healthcare impacts
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
- Long-Term Effects of COVID-19
- Parvovirus B19 Infection Studies
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- HIV Research and Treatment
- Biosensors and Analytical Detection
- Infection Control and Ventilation
- Vaccine Coverage and Hesitancy
- Tuberculosis Research and Epidemiology
- Viral Infections and Immunology Research
- Syphilis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Inflammatory Biomarkers in Disease Prognosis
- Clostridium difficile and Clostridium perfringens research
- Systemic Sclerosis and Related Diseases
Dokuz Eylül University
2011-2025
Office of Infectious Diseases
2024
Dokuz Eylül Üniversitesi Hastanesi
2020
Limited data are available on the short- to midterm levels of antibodies CoronaVac vaccine and quantitative change in humoral response after homologous or heterologous booster doses. In this prospective cohort study, we evaluated anti-receptor-binding domain (RBD) immunoglobulin G (IgG) two doses heterologous/homologous administration among healthcare workers a university hospital Turkey. Quantitative anti-RBD IgG antibody were measured at first fourth months 560 who had completed vaccine,...
Syndromic diagnosis by multiplex nucleic acid amplification tests is the most practical approach to respiratory tract infections since symptoms are rarely agent-specific. The aim of this study was investigate viruses in children admitted a university hospital with acute infection during last 8 years polymerase chain reaction (PCR) assay. A total 3162 samples collected from between April 2011 and 2018 tested real-time PCR Two different commercial assays were used period,...
Because of the widespread use CT in diagnosis COVID 19, indeterminate presentations such as single, few or unilateral lesions amount to a considerable number. We aimed develop new classification and structured reporting system on imaging (COVID-19 S) that would facilitate COVID-19 most accurate way.
This study aimed to evaluate the effectiveness of algorithm used in HIV diagnosis and propose an effective new for rapid diagnosis. In accordance with CDC algorithm, our laboratory uses Architect HIVAg/Ab screening Geenius HIV1/2 Artus HIVirus‐1 QS‐RGQ confirmation. The test was as a reflex HIV‐1‐RNA required clinician order. performed 82,882 sera found be reactive 262 (0.3%). HIV‐antibody confirmatory testing on 79% samples test, presence HIV‐1 antibodies confirmed 51% (105/206). Half...
Abstract Background Vaccine-induced neutralizing antibodies (NAbs) are key for COVID-19 protective-immunity. As the efficacy of SARS-CoV-2 vaccines declines over time and variants virus continue to emerge, need booster doses vaccine remains on agenda. The aim this study was assess NAbs dynamics its correlation with anti-RBD IgG levels during nine-month follow-up period after primary-CoronaVac vaccination vaccinations evaluate strategies. Methods This prospective longitudinal observational...
Although seasonal human coronaviruses (HCoVs) have long been recognized as respiratory tract viruses, the newly identified SARS-CoV-2 caused a pandemic associated with severe failure. We aimed to evaluate incidence of COVID-19 infection in patients diagnosed three tertiary teaching hospitals, both and without prior confirmed HCoV infection, compare these cohorts terms contraction.
To evaluate the distribution and characteristics of respiratory viral pathogens to assess epidemiological data, clinical features, prognoses infected children in a pediatric emergency department during COVID-19 pandemic.Between September 1, 2020, April 30, 2021, patients aged between 0 18 years arrived at were tested by nasopharyngeal/tracheal specimen polymerase chain reaction for both SARS-CoV-2 other pathogens. Demographics, symptoms, laboratory radiologic investigations, viruses detected...
Objective: It is important to put forward the characteristics of COVID-19 cases fight disease effectively. The aim this study determine epidemiological in Turkey. And also risk factors associated with intensive care unit (ICU) admission and death. Methods: In cross-sectional study, confirmed who applied a University Hospital Turkey between March 19th June 11th, 2020, were analyzed. Variables such as epidemic trend, case fatality rate, need for hospitalization, ICU mortality calculated....
We aimed to evaluate the performance of current algorithm HIV diagnosis that has been performed for four years. Results Ag/Ab tests, anti-HIV 1/2 confirmatory HIV-1 RNA tests and time official results be approved were evaluated.
The typing of non-tuberculous mycobacteria (NTM) is important from a clinical and epidemiological perspective. polymerase chain reaction-restriction enzyme analysis (PRA) method DNA sequence were utilized to target gene region that codes the 65-kDa heat-shock protein for 150 suspected NTM samples isolated respiratory tract. Mycobacterium abscessus, xenopi, fortuitum , peregrinum most frequently found by both methods. Six isolates could not be defined PRA as Nocardia cyriacigeorgica,...
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Automated chemiluminescent microparticle immunoassays (CMIAs) are the most common first step at high-volume laboratories for syphilis screening. If initial screening test is reactive, 1 more treponemal required, resulting in increased cost. In this multicenter study, we aimed to determine correlation between CMIA signal-to-cutoff ratio (S/Co) and confirmatory tests reduce unnecessary testing.Eight hospitals from 5 provinces participated study. All used Architect Syphilis TP (Abbott...
To evaluate the frequency of abdominal computed tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19) and interrogate relationship between CT patient demographic features, clinical findings, laboratory test results as well atherosclerosis score aorta.This study was designed a multicenter retrospective study. The 1.181 positive symptoms from 26 tertiary medical centers polymerase chain-reaction for severe acute respiratory syndrome 2 were reviewed. ischemic...
Serological tests detecting antibodies for Epstein-Barr virus (EBV) antigens are frequently used to define infection status. Several new automated assays available this purpose. We compared the performance of Architect, Immulite, Vidas, and Euroimmune immunofluorescence (IFA)/enzyme-linked immunosorbent (ELISA) detection EBV viral capsid antigen (VCA) immunoglobulin M (IgM), VCA IgG, nuclear (EBNA)-1 IgG. The routine diagnosis in our laboratory is done by anti-EBV IgM IFT, IgG anti-EBNA-1...
Purpose: The risk of cytomegalovirus (CMV) reactivation following allogeneic hematopoietic stem cell transplantation (ASCT) reaches 30-50%, and there are numerous diagnostic tests to detect CMV replication. most common used in this group patients include 65kDa phosphoprotein (pp65) antigenemia immunofluorescence assay nucleic-acid-based quantitative CMV-DNA polymerase chain reaction (qPCR). Material Methods: In study, who underwent ASCT developed positivity from 2009 2016 our hospital were...
ABSTRACT Background This study is aimed at providing information about the timing of booster doses and antibody kinetics in healthcare workers. Methods research extends a prospective cohort conducted Dokuz Eylul University Hospital Turkey, covering period from March 2021 to December 2021. During this timeframe, levels health workers were measured four different time points. The associations with gender, age, occupation, body mass index (BMI), chronic disease, smoking analyzed. Results There...
Measles, rubella, mumps and chickenpox infections are among the childhood diseases that can be prevented by vaccination. Healthcare workers at greater risk of transmitted through contact with patients' respiratory secretions, infected blood body fluids. Students studying in field health encountering infectious as much healthcare personnel during their internship practice experience institutions education. In addition, due to these students becoming a source contamination patients they...
Abstract Objective Impaired gastrointestinal (GI) mucosa and immunosuppressant therapies increase the risk of secondary infection in patients with inflammatory bowel disease (IBD). This study evaluated detection pathogens children IBD using a panel (GP). is first to compare this method clinical data from pediatric patients. Methods Children newly diagnosed or experiencing flares were included. Demographic data, laboratory findings, treatments, treatment durations, activity analyzed. Stool...
To determine the existence of SARS-CoV-2 in peritoneal fluid to assess risk exposure through surgical smoke and aerosolization threatening healthcare workers during abdominal surgery. is a respiratory virus possible ways viral transmission are droplets, close contact, fecal-oral route. Surgeries pose for due contact with patients. Aerosolized particles may be inhaled via leaked CO2 laparoscopic procedures produced by electrocautery. All data 8 patients, who were tested positive COVID-19,...
Amaç: Hasta memnuniyeti, herhangi bir sağlık sisteminde hizmet kalitesini ölçmek için yaygın olarak kullanılan göstergedir. Bu çalışmada Dokuz Eylül Üniversitesi Uygulama ve Araştırma Hastanesi Merkez Laboratuvarı kalite göstergesi 2021 2022 yıllarında hastaların laboratuvar hizmetlerinden memnuniyet düzeylerini uygulanan anket sonuçlarının değerlendirilmesi memnuniyetsizlik nedenlerinin gözden geçirilmesi amaçlandı. Gereç Yöntemler: Veriler, her yıl Ocak ile Ekim ayı arasında...