Semra Topçu

ORCID: 0000-0003-1819-4221
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About
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Research Areas
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Health and Disease Prevention
  • Stroke Rehabilitation and Recovery
  • Ovarian function and disorders
  • Cardiac Imaging and Diagnostics
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Function and Risk Factors
  • Liver Disease Diagnosis and Treatment
  • Intensive Care Unit Cognitive Disorders
  • Systemic Lupus Erythematosus Research
  • Family and Patient Care in Intensive Care Units
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Acute Ischemic Stroke Management
  • Dialysis and Renal Disease Management
  • Blood Pressure and Hypertension Studies
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiac Health and Mental Health
  • Vasculitis and related conditions
  • Atrial Fibrillation Management and Outcomes
  • Streptococcal Infections and Treatments
  • Health Education and Validation
  • Pharmaceutical studies and practices
  • Mechanical Failure Analysis and Simulation
  • Health Promotion and Cardiovascular Prevention
  • Inflammasome and immune disorders

Nightingale Hospital
2021-2024

Istanbul Bilim University
2021-2024

Koç University
2014-2020

Marmara University
2017

Başkent University
2001-2009

Institute of Cardiology
2006

Abstract Background Statins improve endothelial functioning in patients with coronary artery disease and hypercholesterolemia, while substantially little is known about induced changes myocardial microcirculation. However, although previous studies have suggested that microvascular abnormalities dysfunction responsible for slow flow (SCF), there no study investigating possible effects of statins on function SCF. Hypothesis We prospectively investigated the short‐term lipid‐lowering therapy...

10.1002/clc.20140 article EN Clinical Cardiology 2007-09-01

<i>Background:</i> Coronary flow reserve (CFR) reflects the functional capacity of microcirculation to adapt blood demand during increased cardiac work. In this study, CFR hemodialysis patients with angiographically normal coronary arteries was evaluated using transthoracic second harmonic Doppler echocardiography. <i>Methods and Results:</i> Ten patients, 14 sex-, age- left ventricular mass index-matched hypertensive controls underwent echocardiographic examination....

10.1159/000087579 article EN Nephron Clinical Practice 2005-08-19

Background— Elevated serum bilirubin concentrations protect against atherosclerotic diseases; however, it is not clear whether higher in physiological ranges work favor of the cardiovascular system younger persons with no risk factors. Accordingly, we investigated effects high, intermediate, and low on coronary flow reserve (CFR). Methods Results— Fifty-two healthy subjects hyperbilirubinemia (total 1.43±0.33 mg/dL; mean age 35.9±7.3), 55 intermediate level bilirubin: 0.69±0.11 age:...

10.1161/01.atv.0000185806.61430.7c article EN Arteriosclerosis Thrombosis and Vascular Biology 2005-09-09

Abstract Background Self‐efficacy has been shown to play an important role in rehabilitation outcomes of stroke patients. Aim This study aimed determine the validity and reliability a Turkish translation Stroke Self‐Efficacy Questionnaire. Methods methodological was conducted private acute unit Istanbul, Turkey. After obtaining Institutional Review Board's approval site consent, translated version 13‐item Likert‐type scaled questions tested for language content validity. A pilot with 10...

10.1111/ijn.12646 article EN International Journal of Nursing Practice 2018-03-25

BackgroundCardiovascular disease is the number one cause of death worldwide. However, there not enough data exploring student nurses' understanding, knowledge, and awareness cardiovascular disease.

10.1177/1474515114540554 article EN European Journal of Cardiovascular Nursing 2014-06-30

Using high-fidelity simulations to facilitate student learning is an uncommon practice in Turkish nursing programs. The aim of the present study was understand students' perceptions use simulation courses. Subjects included 36 senior students taking intensive care course. This revealed that ideal method promoting by helping transfer theory into practice, build confidence and teamwork, raise professional awareness.

10.1097/nne.0000000000000134 article EN Nurse Educator 2015-02-18

Background Intensive care units frequently use the Glasgow Coma Scale to objectively assess patients’ levels of consciousness. Interobserver reliability scores is critical in determining degree impairment. Objective To evaluate interobserver intensive unit scores. Methods This prospective observational study evaluated scoring agreement among 21 nurses and 2 independent researchers who assessed 202 patients with neurosurgical or neurological diseases. Each assessment was completed...

10.4037/ccn2020200 article EN Critical Care Nurse 2020-08-01

Summary Background Women with polycystic ovary syndrome (PCOS) are thought to have increased cardiovascular risk. Metformin therapy reduces whole‐body insulin resistance (IR) in patients type‐2 diabetes mellitus (DM). Objective As accompanying PCOS may be reversed by metformin therapy, we hypothesized that might improve coronary microvascular functions women and IR. Patients methods We treated 16 IR metformin, measured flow reserve (CFR) at the beginning after 6 months of using transthoracic...

10.1111/j.1365-2265.2006.02551.x article EN Clinical Endocrinology 2006-06-06

BACKGROUND: It is thought that women with polycystic ovary syndrome (PCOS) are at increased risk of developing cardiovascular diseases. METHODS: In this study, we used transthoracic echocardiography to measure coronary flow reserve (CFR) in 28 PCOS and 26 healthy women. RESULTS: The the control groups were similar terms age (27.1 ± 4.5 versus 28.8 4.4 years) BMI (26.6 5.7 24.7 kg/m2). Fasting insulin levels homeostasis model assessment resistance index higher group. LH, LH/FSH ratio, total...

10.1093/humrep/dei431 article EN Human Reproduction 2005-12-22

To date, there has been no study comparing the possible acute effects on coronary microvascular functions of smoking light cigarettes (those with low tar and nicotine yield) regular cigarettes.Twenty healthy volunteers (8 women 12 men; mean age, 25.8 +/- 5.8 years) were included in a single-blind, open-label, cross-over to compare (containing 0.6 mg nicotine, 8 tar, 9 carbon monoxide) 0.9 flow reserve (CFR). For each participant, CFR values measured at baseline, after 2 or cigarettes, 15...

10.1002/clc.20343 article EN Clinical Cardiology 2009-04-01

Smoking mentholated cigarettes inhibits the metabolism of nicotine and increases systemic exposure to cigarette smoke toxins. However, possible effects smoking on coronary microvascular functions are unknown. We sought investigate whether impairs flow reserve (CFR) more so than regular cigarettes.Twenty otherwise healthy smokers (6 women, 14 men; mean age, 25.6 +/- 6.4 years) 22 non-smoking control subjects were included in study. To compare acute (0.9 mg nicotine, 11 tar, 12 carbon...

10.2143/ac.63.2.2029518 article EN Acta Cardiologica 2008-04-01

Behcet's disease (BD) is characterized with remissions and exacerbations. However, to date, there no study investigate a possible association of activity (active versus inactive period) cardiovascular complications.Forty patients BD were evaluated in both active period. For the control group 45 healthy volunteers, age sex matched, registered. Subjects at least 15-day lesion-free period regarded period, subjects any oral, skin, and/or genital lesion was as In each subject coronary diastolic...

10.1080/07853890701204866 article EN Annals of Medicine 2007-01-01

10.1016/j.iccn.2020.102801 article EN Intensive and Critical Care Nursing 2020-02-05

limitations in the world and Turkey. For this reason, Stroke symptoms can be very stressful for caregivers it a burden of health care system. Positive patient outcomes achieved with proper management treatment process. Treatment plan according to stroke patients psychologic adaptations such as self-efficacy ability self-care activities. The aim study is provide context relationship self-efficacy, quality life stroke. Özetİnme tüm dünyada ve ülkemizde sakatlıklara kısıtlılıklara neden olan...

10.14687/jhs.v14i2.4503 article TR Journal of Human Sciences 2017-04-24

It is still not clear whether mitral valve prolapse (MVP) a risk factor for ischemic stroke. The aim of this study was to evaluate uncomplicated MVP silent cerebral events. Fifty-two patients with and 46 control subjects without were included in the study. All evaluated infarct (SCI) magnetic resonance imaging. Five (9.6%) who had but no other factors events SCI. results suggest that SCI, should receive anti-platelet-aggregating drugs.

10.1080/00207450590957836 article EN International Journal of Neuroscience 2005-01-01

Introduction: The flipped classroom approach is based on shared responsibility for learning by students and teachers, empowering to take an active role in the process. While there have been positive outcomes use of this model nursing theoretical practical courses, its implementation within educational system limited. Aim: This study was planned evaluate effectiveness education students, specifically teaching "Cardiovascular System Examination" topic Health Assessment course. It a comparative...

10.16919/bozoktip.1377947 article EN Bozok Tıp Dergisi 2024-03-12
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