A5003046546- Insect Pest Control Strategies
- Alzheimer's disease research and treatments
- Amino Acid Enzymes and Metabolism
- Protein Structure and Dynamics
- Electrochemical sensors and biosensors
- Insect and Pesticide Research
- Computational Drug Discovery Methods
- Psidium guajava Extracts and Applications
- Insect Resistance and Genetics
- Trace Elements in Health
- Insect Utilization and Effects
Universidad Santo Tomás
2018-2019
Industrial University of Santander
2011
University of Massachusetts Amherst
2010
β-2-Microglobulin (β2m) self-associates into fibrillar amyloid deposits in the musculoskeletal system of patients undergoing hemodialysis treatment. Previous studies have shown that stoichiometric amounts Cu(II) at near physiological conditions can cause β2m to organize native-like dimers prior forming fibrils. Here, we report results from selective covalent labeling reactions combined with mass spectrometry provide insight amino acid residues mediate dimer formation wild-type protein. Using...
The main pathogenic process underlying dialysis-related amyloidosis is the accumulation of β-2-microglobulin (β2m) as amyloid fibrils in musculoskeletal system, and some evidence suggests that Cu(II) may play a role β2m formation. Cu(II)-induced fibril formation preceded by discrete, oligomeric intermediates, including dimers, tetramers, hexamers. In this work, we use selective covalent labeling reactions combined with mass spectrometry to investigate amino acids responsible for mediating...
The insecticidal and antifeedant activities of five 7-chloro-4-(1H-1,2,3-triazol-1-yl)quinoline derivatives were evaluated against the maize armyworm, Spodoptera frugiperda (J.E. Smith). These hybrids prepared through a copper-catalyzed azide alkyne cycloaddition (CuAAC, known as click reaction) displayed larvicidal properties with LD50 values below 3 mg/g insect, triazolyl-quinoline hybrid 6 showed an 0.65 making it 2-fold less potent than methomyl, which was used reference insecticide...
Abstract Skin irritation has been reported to be the main adverse effect of excessive use N,N-diethyl-m-toluamide (DEET) and ethyl 3-acetyl(butyl)amino (IR3535) commercial repellents. Therefore, there is an interest in alternatives natural origin such as essential oils (EOs) major compounds, which have repellent effects but no contraindications. The purpose present study was identify selected terpenes on Aedes aegypti Linnaeus, 1762 (Diptera: Culicidae) by silico analysis based their...
ResumenLa capacidad antioxidante de extractos plantas ha sido estudiada por técnicas voltamperométricas gracias a su sensibilidad, selectividad, bajo costo, simplicidad y rapidez.En esta investigación se utilizó la Voltamperometría Cíclica para estudiar el potencial en preservación etanólicos hojas espinaca (Spinacia oleracea).Los obtuvieron luego macerar con etanol industrial llevar ultrasonido.Los barridos potenciométricos los 0, 7 15 días preparación realizaron una solución amortiguadora...