A5013976203- Malaria Research and Control
- Mosquito-borne diseases and control
- Bird parasitology and diseases
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Insect Pest Control Strategies
- Insect Resistance and Genetics
- Avian ecology and behavior
- Insect symbiosis and bacterial influences
- Pesticide Residue Analysis and Safety
- Insect and Pesticide Research
- Iron Metabolism and Disorders
- Insect and Arachnid Ecology and Behavior
- Pharmacological Effects and Assays
- Influenza Virus Research Studies
- Insect Utilization and Effects
- Animal Disease Management and Epidemiology
- Coccidia and coccidiosis research
- Animal Behavior and Reproduction
- Health Policy Implementation Science
- Microbial infections and disease research
- Viral Infections and Outbreaks Research
- Pesticide Exposure and Toxicity
- Veterinary medicine and infectious diseases
- Food Supply Chain Traceability
U.S. President's Malaria Initiative
2020-2025
United States Agency for International Development
2023-2025
Johns Hopkins University
2017-2021
London School of Hygiene & Tropical Medicine
2020
National Office for Sanitation of Senegal
2020
Université des Sciences, des Techniques et des Technologies de Bamako
2020
Abt Associates (Nepal)
2020
Schulman, Ronca & Bucuvalas
2020
Associates Research
2020
University of California, Davis
2012-2018
Zika (ZIKV) and dengue viruses (DENV) are transmitted to humans by Aedes mosquitoes. However, the molecular interactions between vector ZIKV remain largely unexplored. In this work, we further investigated tropism of in two different aegypti strains show that virus infection kinetics, tissue migration, susceptibility differ mosquito strains. We also compare transcriptome changes upon or DENV demonstrating 40% mosquito's midgut infection-responsive is virus-specific at seven days after...
Transmission of dengue virus (DENV) requires successful completion the infection cycle in Aedes aegypti vector, which is initiated midgut tissue after ingestion an infectious blood meal. While certain Ae. midgut-associated bacteria influence infection, little known about fungi (mycobiota), and how its members might susceptibility to DENV infection. We show that a Talaromyces (Tsp_PR) fungus, isolated from field-caught aegypti, render mosquito more permissive This modulation attributed...
The unprecedented rate of change in the Arctic climate is expected to have major impacts on emergence infectious diseases and host susceptibility these diseases. It predicted that malaria parasites will spread both higher altitudes latitudes with global warming. Here we show for first time avian Plasmodium transmission occurs North American Arctic. Over a latitudinal gradient Alaska, from 61°N 67°N, collected blood samples resident migratory bird species. We found residents hatch year birds...
The role of vectors in the transmission avian malaria parasites is currently understudied. Many studies that investigate parasite-vector relationships use limited trapping techniques and/or identify potential competent field such ways cannot distinguish between an infected or infectious vector. Without multiple address specific biology diverse mosquito species, and without looking at infection status individual mosquitoes, it not possible to make dependable conclusions on mosquitoes...
Millions of pyrethroid LLINs have been distributed in Mali during the past 20 years which, along with agricultural use, has increased selection pressure on malaria vector populations. This study investigated resistance intensity and susceptible status vectors to alternative insecticides guide choice for IRS effective control vectors.
Abstract Background Malaria remains one of the main causes morbidity and mortality in Cameroon. To inform vector control intervention decision making, malaria surveillance was conducted monthly from October 2018 to September 2020 five selected sentinel sites (Gounougou Simatou North, Bonabéri, Mangoum Nyabessang South). Methods Human landing catches (HLCs), U.S. Centers for Disease Control Prevention (CDC) light traps, pyrethrum spray (PSCs) were used assess density, species composition,...
Trypanosoma anguiformis n. sp. and polygranularis are described from the African olive sunbird, Cyanomitra olivacea, Latham's forest francolin, Francolinus lathami, respectively, based on morphology of their hematozoic trypomastigotes partial sequences small subunit ribosomal RNA gene. Both new species belong to group non-striated avian trypanosomes (<30 µm in length average) with kinetoplast situated close posterior end body. can be readily distinguished other due its markedly attenuated...
Following agricultural use and large-scale distribution of insecticide-treated nets (ITNs), malaria vector resistance to pyrethroids is widespread in sub-Saharan Africa. Interceptor® G2 a new dual active ingredient (AI) ITN treated with alpha-cypermethrin chlorfenapyr for the control pyrethroid-resistant vectors. In anticipation these being more widely distributed, testing was conducted develop susceptibility bioassay protocol gather information.Bottle tests were using five concentrations at...
Mosquitoes are vectors for some of the most devastating diseases on planet. Given centrality acoustic sensing in precopulatory behavior these vectors, use an exogenous stimulus offers potential interfering with courtship insects. Previous research acoustotactic response mosquitoes has been conducted tethered preparations using low-intensity sound stimuli. To quantify differences responses between mosquitos distinct sex and species, we examined effects incidental stimuli flight free-flying...
Here we describe Haemoproteus (Haemoproteus) multivolutinus n. sp. from a tambourine dove (Turtur timpanistria) of Uganda and paramultipigmentatus (Haemosporida, Haemoproteidae) the Socorro common ground (Columbina passerina socorroensis) Island, Mexico. These parasites are described based on morphology their blood stages segments mitochondrial cytochrome b gene that can be used for molecular identification diagnosis these species. Gametocytes H. possess rod-like pigment granules evenly...
We report experimental evidence for bioconcentration of a low-pathogenicity avian influenza virus (H6N8) in the tissue freshwater clams. Our results support concept that clams may provide an effective tool use early detection A viruses aquatic environments.
The Socorro dove Zenaida graysoni, endemic to Island, was last reported in the wild 1972. Fortunately, species has been propagated zoos Europe and United States, plans are under way re-introduce it its native habitat. This will be first known attempt return a bird extinct ancestral island. In order assess disease threats may face, avifauna of with specific focus on ground doves Columbina passerina socorroensis mourning macroura, as well captivity, were screened for blood parasites genera...
Haemoproteus (Haemosporida, Haemoproteidae) is the largest genus of avian haemosporidian parasites, some species which cause lethal diseases in birds. Subgenera Parahaemoproteus and are usually accepted this genus; these parasites transmitted by biting midges (Ceratopogonidae) hippoboscid flies (Hippoboscidae), respectively. As yet, have not been reported to infect doves pigeons (Columbiformes), birds be (Ceratopogonidae). Applying microscopy PCR based methods, we identified mitochondrial...
We have developed a novel preparation to kill mosquitoes from an abundant soil bacterium, Chromobacterium sp. Panama. This is air-dried powder containing no live bacteria, and it can be incorporated into attractive bait fed directly mosquito larvae. demonstrate that the has broad spectrum activity against larval form of responsible for transmission malaria dengue, chikungunya, yellow fever, West Nile, Zika viruses, as well larvae are already resistant commonly used mosquitocidal chemicals....
Avian malaria (Plasmodium spp.) has been implicated in the decline of avian populations Hawaiian Islands and it is generally agreed that geographically isolated immunologically naïve bird are particularly vulnerable to pathogenic effects invasive parasites. In order assess potential disease risk avifauna Socorro Island, México, we surveyed for Plasmodium isolates from 1,300 resident field-caught mosquitoes. Most them were identified as Aedes (Ochlerotatus) taeniorhynchus (Wiedemann, 1821),...
Abstract The scale up of indoor residual spraying (IRS) and insecticide treated nets have contributed significantly to global reductions in malaria prevalence over the last two decades. However, widespread pyrethroid resistance has necessitated use new more expensive insecticides for IRS. Partial IRS with pirimiphos-methyl experimental huts houses a village-wide trial was evaluated against Anopheles gambiae s.l. northern Ghana. Four different scenarios which either only top or bottom half...
Avian malaria vector competence studies are needed to understand more succinctly complex avian parasite-vector-relations. The lack of trials may be attributed the difficulty obtaining gametocytes for majority Plasmodium species and lineages. To conduct infectivity assays those spp. lineages that refractory in vitro cultivation, it is necessary obtain preserve short periods sufficient viable merozoites infect naïve donor birds used as gametocyte donors mosquitoes. Currently, there only one...
From August 2020 to June 2021, we assessed the efficacy of SumiShield 50WG (clothianidin), Fludora Fusion 56.25WP-SB (mixture clothianidin and deltamethrin) Actellic 300CS (pirimiphos-methyl) in experimental huts when partially sprayed against wild, free-flying populations Anopheles gambiae s.l. Tiassalé, Côte d'Ivoire. A one-month baseline period mosquito collections was conducted determine density resting behavior unsprayed huts, after which two treatments partial indoor residual spraying...
Eight adult female dairy goats received one subcutaneous administration of tulathromycin at a dosage 2.5 mg/kg body weight. Blood and milk samples were assayed for the common fragment tulathromycin, respectively, using liquid chromatography/mass spectrometry. Pharmacokinetic disposition was analyzed by noncompartmental approach. Mean plasma pharmacokinetic parameters (±SD) following single‐dose as follows: C max (121.54 ± 19.01 ng/mL); T (12 12–24 h); area under curve AUC 0→∞ (8324.54...
Currently, there are very few studies of avian malaria that investigate relationships among the host-vector-parasite triad concomitantly. In current study, we experimentally measured vector competence several Culex mosquitoes for a newly described parasite, Plasmodium homopolare. Song sparrow (Melospiza melodia) blood infected with low P. homopolare parasitemia was inoculated into naïve domestic canary (Serinus canaria forma domestica). Within 5 to 10 days post infection (dpi), unexpectedly...