A5081795451- Cardiomyopathy and Myosin Studies
- Congenital heart defects research
- Cardiovascular Function and Risk Factors
- Neurogenetic and Muscular Disorders Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac pacing and defibrillation studies
- Anesthesia and Pain Management
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac electrophysiology and arrhythmias
- Vitamin K Research Studies
- Muscle Physiology and Disorders
- Spine and Intervertebral Disc Pathology
- Mitochondrial Function and Pathology
- Cardiovascular Effects of Exercise
- Pulmonary Hypertension Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Takotsubo Cardiomyopathy and Associated Phenomena
- Mechanical Circulatory Support Devices
- Pericarditis and Cardiac Tamponade
- Protein Tyrosine Phosphatases
- Infectious Aortic and Vascular Conditions
- Coronary Artery Anomalies
- Heart Failure Treatment and Management
- Ultrasound in Clinical Applications
Institute of Cardiology
2021-2022
Children's Memorial Health Institute
2011-2022
Instytut Matki i Dziecka
2011
Wroclaw Medical University
1979
Background: Left ventricular noncompaction (LVNC) is a genetically and phenotypically heterogeneous cardiomyopathy in which myocardium consists of two, distinct compacted noncompacted layers, prominent trabeculations deep intertrabecular recesses are present. LVNC associated with an increased risk heart failure, atrial arrhythmias thromboembolic events. Familial forms primary sinus bradycardia have been attributed to alterations HCN4. There very few reports about the association between HCN4...
Background: Left ventricular non-compaction (LVNC) is a rare cardiomyopathy typically involving the left ventricle (LV); however, right (RV) can also be affected. This case-control study aimed to assess morphology and function of LV RV in children with LVNC. Methods: Sixteen (13 ± 3 years, six girls) LVNC were compared 16 sex- age-matched controls. evaluated cardiovascular magnetic resonance (CMR) studies. Additionally, global radial (GRS), circumferential (GCS), longitudinal strain (GLS)...
Background: Left ventricular noncompaction cardiomyopathy (LVNC) is a rare cardiac disorder characterised by the presence of two-layer myocardium with prominent trabeculation, intertrabecular deep depressions and an increased risk heart failure, atrial arrhythmias systemic thromboembolic events in affected patients. The heterogeneous molecular aetiology solved 10%–50% patients more frequently involves sarcomeric, cytoskeletal or ion channel protein dysfunction—mainly related to causative...
Background: Left ventricular noncompaction (LVNC) is a genetically and phenotypically heterogeneous cardiomyopathy characterized by two-layered myocardium consisting of compacted noncompacted segments, prominent trabeculations, intertrabecular recesses. Patients with LVNC are at increased risk to develop heart failure, atrial arrhythmias, and/or systemic thromboembolic events. Familial forms primary sinus bradycardia have been attributed mutations in HCN4. There very few reports about the...
Background: Left ventricular noncompaction (LVNC) is a genetically determined cardiomyopathy that occurs following disruption of endomyocardial morphogenesis. The purpose this study was to identify the clinical characteristics and genetic profile children with LVNC. Methods: From February 2008 July 2020, total 32 (median 11.5 years) LVNC were prospectively enrolled followed up for median 4.02 years. Diagnosis made based on characteristic features in echocardiography cardiovascular magnetic...
Background: Left ventricular noncompaction (LVNC) is a distinct cardiomyopathy characterized by the presence of two-layer myocardium with prominent trabeculation and deep intertrabecular recesses. The diagnosis LVNC can be challenging because diagnostic criteria are not uniform. aim our study was to evaluate echocardiographic CMR findings in group children isolated LVNC. Methods: From February 2008 July 2021, pediatric patients under 18 years age at time evidence were prospectively enrolled....
Background: Left ventricular noncompaction (LVNC) is a distinct cardiomyopathy characterized by the presence of two-layer myocardium with prominent trabeculation and deep intertrabecular recesses. The diagnosis LVNC can be challenging because diagnostic criteria are not uniform. aim our study was to evaluate echocardiographic CMR findings in group children isolated LVNC. Methods: From February 2008 July 2021, pediatric patients under 18 years age at time evidence were prospectively enrolled....
Background: Left ventricular noncompaction (LVNC) is a genetically determined cardiomyopathy, that occurs following disruption of endomyocardial morphogenesis. The purpose this study was to identify the clinical characteristics and genetic profile children with LVNC. Methods: From February 2008 July 2020, total 32 (median 11.5 years) LVNC were prospectively enrolled followed up for median 4.02 years. Diagnosis made based on characteristic features in echocardiography cardiovascular magnetic...