- scientometrics and bibliometrics research
- Advanced Mathematical Theories and Applications
- Biochemical Acid Research Studies
- COVID-19 epidemiological studies
- Ion channel regulation and function
- Plant nutrient uptake and metabolism
- Microbial Metabolites in Food Biotechnology
- Algebraic Geometry and Number Theory
- Vibrio bacteria research studies
- Advanced Mathematical Identities
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Consumer Perception and Purchasing Behavior
- COVID-19 Pandemic Impacts
- Wikis in Education and Collaboration
- Diet, Metabolism, and Disease
- Advanced Combinatorial Mathematics
- Microbial metabolism and enzyme function
- Mathematical Dynamics and Fractals
- Academic Publishing and Open Access
- Protein Kinase Regulation and GTPase Signaling
- Lipid Membrane Structure and Behavior
- Trypanosoma species research and implications
- Academic Writing and Publishing
- Medicinal Plants and Neuroprotection
Columbia University
2019-2024
Korea Institute of Science & Technology Information
2012-2024
Korea Institute of Science and Technology
2013-2023
Catholic Kwandong University
2019-2022
Columbia College
2019
Royal College of Physicians
2019
Seoul National University
2007-2015
Hankuk University of Foreign Studies
2012
Hyundai Motors (South Korea)
2004
Hallym University
1997
Introduction Scientific collaboration is an important mechanism that enables the integration of least developed countries into research activities. In present study, we use order author signatures and addresses for correspondence in scientific publications as variables to analyze interactions between very high (VHHD), (HHD), medium (MHD), low human development (LHD). Methodology We identified all documents published 2011 2015 journals included Science Citation Index-Expanded categories'...
Significance The human calcium-sensing receptor maintains a stable concentration of calcium in the blood. Naturally occurring mutations are linked to homeostatic disorders including hypercalcemia and hypocalcemia. Modulation function can provide therapeutic relief these conditions. structures absence presence various allosteric modulators reveal mechanism by which modifiers up- or down-regulate function. We have captured symmetric forms homodimeric both at rest upon stimulation concluded...
Metabotropic GABA B receptors mediate a significant fraction of inhibitory neurotransmission in the brain. Native receptor complexes contain principal subunits B1 and B2 , which form an obligate heterodimer, auxiliary subunits, known as potassium channel tetramerization domain-containing proteins (KCTDs). KCTDs interact with modify kinetics signaling. Little is about molecular mechanism governing direct association functional coupling these proteins. Here, we describe high-resolution...
Chagas disease is a chronic, tropical, parasitic disease, endemic throughout Latin America. The large-scale migration of populations has increased the geographic distribution and cases have been observed in many other countries around world. To strengthen critical mass knowledge generated different countries, it essential to promote cooperative translational research initiatives. We analyzed authorship scientific documents on indexed Medline database from 1940 2009. Bibliometrics was used...
Inhibiting high-voltage-activated calcium channels (HVACCs; CaV1/CaV2) is therapeutic for myriad cardiovascular and neurological diseases. For particular applications, genetically-encoded HVACC blockers may enable channel inhibition with greater tissue-specificity versatility than achievable small molecules. Here, we engineered a inhibitor by first isolating an immunized llama nanobody (nb.F3) that binds auxiliary CaVβ subunits. Nb.F3 itself functionally inert, providing convenient vehicle...
Reflecting sex and gender characteristics in biomedical research is critical to improving health outcomes reducing adverse effects from medical treatments. This study investigates the impact of sex/gender-specific funding policies journal editorial standards on integration sex/gender analysis publications. Using data United States, Canada, Kingdom, other countries between 2000 2021, we assessed how these influenced output fields medicine life sciences. Our findings show that with progressive...
Background Although researchers have worked in collaboration since the origins of modern science and publication first scientific journals eighteenth century, this phenomenon has acquired exceptional importance last several decades. Since mid-twentieth new knowledge been generated from within an ever-growing network investigators, working cooperatively research groups across countries institutions. Cooperation is a crucial determinant academic success. Objective The aim present paper to...
The ureide pathway, which mediates the oxidative degradation of uric acid to (S)-allantoin, represents late stage purine catabolism in most organisms. details metabolism remained elusive until complete pathway involving three enzymes was recently identified and characterized. However, molecular exclusive production one enantiomer allantoin this are still undefined. Here we report crystal structure 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) decarboxylase, catalyzes last reaction a...
Collaboration is one of the defining features contemporary scientific research, and it particularly important with regard to neglected diseases that primarily affect developing countries.The present study has identified publications on leishmaniasis in Medline database from 1945 2010, analyzing them according bibliometric indicators statistics social network analysis. Examining aspects such as production, diachronic evolution, collaboration configuration research groups field, we have...
Several Fusarium species produce the polyketide mycotoxin zearalenone (ZEA), a causative agent of hyperestrogenic syndrome in animals that is often found F. graminearum-infected cereals temperate regions. The ZEA biosynthetic cluster genes PKS4, PKS13, ZEB1 and ZEB2 encode reducing synthase, non-reducing an isoamyl alcohol oxidase transcription factor respectively. In this study, production two isoforms (ZEB2L ZEB2S) from gene graminearum via alternative promoter was characterized. ZEB2L...
Humans acquire and accumulate knowledge through language usage eagerly exchange their for advancement. Although geographical barriers had previously limited communication, the emergence of information technology has opened new avenues exchange. However, it is unclear which communication pathway dominant in 21st century. Here, we explore path diffusion century using Wikipedia, largest communal dataset. We evaluate similarity shared between population groups, distinguished based on usage. When...
Questionable publications have been accused of "greedy" practices; however, their influence on academia has not gauged. Here, we probe the impact questionable through a systematic and comprehensive analysis with various participants from compare results those unaccused counterparts using billions citation records, including liaisons, i.e., journals publishers, prosumers, authors. attribute publisher-level self-citations to while limiting journal-level self-citations; yet, conventional...
The objective of this article is to bring together geographic, marketing and economic perspectives examine how far infrastructure development can offset adverse national geographies in aiding involvement the global economy. We use LISREL structural equation modelling investigate relationships between geography, infrastructure, country’s trade foreign direct investment. Results identify key geographic factors affecting market infrastructures (electricity production, telephone lines container...
The COVID-19-related research field has emerged with a number of papers and citations in very short time period. Journals published works have increased their impact factor (IF), which reflects the attention on COVID-19. With publications Web Science, we found that IF journals but more benefits were given to high journals. Highly cited distributed This increases inequality category. In conclusion, our findings imply is vulnerable external events, therefore it supports warn use quantitative...
The recent pandemic stimulated scientists to publish a significant amount of research that created surge citations COVID-19-related papers in short time, leading an abrupt inflation the journal impact factor (IF). By auditing complete set publications Web Science, we reveal here worsened polarization academic journals: IF before was proportional increment IF, which had effect increasing inequality while retaining rankings. We also found most highly cited studies related COVID-19 were...
Civic engagement activities are driven by policy expectations and utilities that focus citizen participation with the idea they will lead to better outcomes. Depending on level of direct participation, citizens can be categorized from dutiful engaged citizens. Measures citizenship, such as fostering a sense ownership active social ensure sustainability future societies have positive impact democratic governance economic development. A systematic review research method was applied collect...
Abstract The recent pandemic stimulated scientists to publish a significant amount of research that created surge citations COVID-19-related publications in short time, leading an abrupt inflation the journal impact factor (IF). By auditing complete set Web Science, we reveal here worsened polarization academic journals: IF before was proportional increment IF, which had effect increasing inequality while retaining rankings. We also found most highly cited studies related COVID-19 were...