A5029330459- Sexual Differentiation and Disorders
- Urological Disorders and Treatments
- Birth, Development, and Health
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Management and Research
- Vasculitis and related conditions
- Neonatal and fetal brain pathology
- Pregnancy and preeclampsia studies
- Pediatric Pain Management Techniques
- Evolutionary Psychology and Human Behavior
- Hormonal and reproductive studies
- Adolescent and Pediatric Healthcare
- Preterm Birth and Chorioamnionitis
- Assisted Reproductive Technology and Twin Pregnancy
- Neuroendocrine regulation and behavior
- Bipolar Disorder and Treatment
- Congenital limb and hand anomalies
- Morphological variations and asymmetry
- Urticaria and Related Conditions
- Renal Diseases and Glomerulopathies
- Childhood Cancer Survivors' Quality of Life
- Pediatric Urology and Nephrology Studies
- Anesthesia and Neurotoxicity Research
Düsseldorf University Hospital
2023-2024
Heinrich Heine University Düsseldorf
2018-2024
University Hospital Cologne
2017
Importance The circumstances under which neonatal hypoglycemia leads to brain damage remain unclear due a lack of long-term data on the neurodevelopment affected children. As result, diagnostic strategies and treatment recommendations are inconsistent. Objective To evaluate whether occurrence severe transitional (defined as having at least 1 blood glucose measurement 30 mg/dL or below) is associated with adverse in midchildhood. Design, Setting, Participants This cohort study using...
The sex difference of the 2D:4D digit ratio (female > male)-a proposed marker for prenatal testosterone exposure-is well established. Studies suggest it already exists in utero and is moderate effect size adulthood. However, evidence claim that reflects androgen action limited, may exhibit lability during childhood. In present study, 244 mothers were recruited course an amniocentesis examination (performed between gestational weeks 14 18). Prenatal (T) estradiol (E) levels determined from...
Abstract Hands and digits tend to be sexually dimorphic may reflect prenatal androgen exposure. In the past years, literature introduced several hand digit measures, but there is a lack of studies in prepubertal cohorts. The available reports more heterogeneous findings compared postpubertal comparability further limited by study design different measurement techniques. present reliability sex differences namely lengths 2D, 3D, 4D, 5D, ratios 2D:4D, 2D:5D, 3D:4D, 3D:5D, 4D:5D, relative rel2,...
Abstract Sex-typed play behavior shows large sex differences and seems to be affected by prenatal hormones. For example, a smaller, more male-typical ratio between the second fourth digit length (2D:4D), proposed marker for testosterone exposure, has been shown related sex-typed preference in childhood. Nevertheless, it is still being debated whether 2D:4D displays stable difference throughout childhood, as there are few longitudinal studies. In present study, children’s was measured on both...
<ns4:p><ns4:bold>Background: </ns4:bold>Simultaneous assessment of steroid hormone concentrations in amniotic fluid is importance for elucidating long-term consequences intrauterine processes, and broad scientific clinical relevance. The objective the study was to develop sensitive specific analytical ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) methods determination human fluid, provide proof-of-concept their applicability.</ns4:p><ns4:p>...
Abstract The 2D:4D digit ratio is commonly used as a surrogate possibly reflecting prenatal testosterone levels. Indirect evidence comes from studies investigating the association between and human characteristics that likely relate to testosterone. In children, sex-typed play reveals large sex differences early in development an influence of likely. Findings on children’s are heterogeneous other influences have been suggested, most all social like siblings, their birth order. current study...
(Abstracted from JAMA Network Open 2024;7:e243683) The most common metabolic condition requiring treatment in neonates is hypoglycemia, with a reported incidence of 15% among all and 50% preexisting risk factors. Transitional hypoglycemia the form, occurring due to stress directly after birth transitioning intrauterine extrauterine life.
Abstract Developmental instability (DI) reflects an organism’s inability to develop ideal phenotype when challenged by genetic and environmental insults. DI can be estimated via the proxy measure of fluctuating asymmetry (FA), i.e., small random deviations from perfect bilateral symmetry observed in morphology paired traits. The mechanisms involved genesis FA human populations are relatively unknown, though animal research indicates that hormonal processes may involved. As maternal stress...
Abstract Since the transition from pediatric and adolescent to adult care often proceeds unaccompanied unplanned, young patients with chronic kidney disease may experience health risks non-adherence after transfer. The psychosocial team at Department of Pediatric Nephrology University Hospital Cologne has therefore developed its local program “TraiN” for aged 13 years older. It combines structure flexibility through predefined content modules that can be individually adapted patients,...