A5038524034- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Biotechnology and Related Fields
- Pharmaceutical Economics and Policy
- Intellectual Property and Patents
- Pneumonia and Respiratory Infections
- Biosimilars and Bioanalytical Methods
- Healthcare Systems and Reforms
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Metabolism and Genetic Disorders
- Global Health Care Issues
- COVID-19 diagnosis using AI
- Renin-Angiotensin System Studies
- Global Health and Epidemiology
- Folate and B Vitamins Research
- Global Maternal and Child Health
- Hormonal Regulation and Hypertension
- Neurological diseases and metabolism
- Education during COVID-19 pandemic
- Infectious Diseases and Mycology
- Healthcare during COVID-19 Pandemic
University of Lübeck
2025
Universidade Federal do Rio de Janeiro
2009-2023
National Education and Research Network
2011
Centro de Estudos e Pesquisa em Saúde Coletiva
2009
At a global level, with the increase in healthcare costs, there is need to assess economic impact of incorporation new technologies different health disorders countries. There scarce information regarding costs incurred use current or diagnostic tests for tuberculosis from vantage point their within systems high-burden The present study aimed mean cost and activity based laboratory diagnosis by means conventional techniques Detect TB®LabTest molecular test kit general high-complexity...
INTRODUCTION: Rapid and accurate tuberculosis detection is critical for improving patient diagnosis decreasing transmission. Molecular assays can significantly increase laboratory costs; therefore, the average time economic impact should be evaluated before implementing a new technology. The aim of this study was to evaluate cost turnaround smear microscopy Xpert assay at university hospital. METHODS: were calculated based on mean activity costing (ABC). RESULTS: 16.6 hours while that 24.1...
The molecular test Xpert MTB/RIF (Xpert) has been recommended for use in the diagnosis of pulmonary tuberculosis (PTB); however, data on cost incorporating it under routine conditions high-burden countries are scarce. clinical impact and costs incurred adopting PTB was evaluated a prospective study conducted from November 2012 to 2013, City Rio de Janeiro, Brazil.The diagnostic therapeutic cascade TB treatment using first stage (S1), sputum smear microscopy (SSM) second (S2). mean associated...
It has long been recognised that the health-related Millennium Development Goals cannot be achieved without strengthened health systems. This article presents most recent World Health Organization framework for strengthening systems and considers how economics research can used to measure achievements against each of goals framework. Benefits incorporating tools into operational are highlighted. Finally, economic placed within an impact assessment facilitates capture considerations in...
INTRODUCTION: The intensification of research and innovation with the creation networks rapid effective molecular tests as strategies for end tuberculosis are essential to avoid late diagnosis eradication disease. We aimed evaluate cost-effectiveness Xpert®MTB/RIF (Xpert) in drug-resistant reference units, scenarios without subsidies, respective cost adjustment today. METHODS: analyses were performed considering criterion effectiveness, negative culture or clinical improvement sixth month...
Abstract Background Molecular tests can allow the rapid detection of tuberculosis (TB) and multidrug-resistant TB (MDR-TB). TB-SPRINT 59-Plex Beamedex® is a microbead-based assay developed for simultaneous spoligotyping MDR-TB. The accuracy cost evaluation new assays technologies are great importance their routine use in clinics research laboratories. aim this study was to evaluate performance at three laboratory centers Brazil calculate its mean (MC) activity-based costing (ABC). Methods...
The present study sought to assess the mean and activity based cost (ABC) of laboratory diagnosis for tuberculosis through application conventional molecular techniques-Xpert®MTB/RIF Genotype®MTBDRplus-in a tertiary referral hospital in Brazil.The ABC formed basis analysis TB diagnosis.The were US$ 4.00 3.24, respectively, bacilloscopy; 6.73 5.27 Lowenstein-Jensen (LJ) culture; 105.42 76.56 drug sensitivity test (DST)-proportions method (PM) LJ; 148.45 136.80 DST-BACTECTM MGITTM 960 system;...
We aimed to evaluate the costs of GenoType® MTBDRplus and MTBDRsl incurred during diagnosis first- second-line drug-resistant tuberculosis (TB) in São Paulo, Brazil.Mean activity-based were calculated a referral laboratory for TB Brazil.The mean cost value USD 19.78 35.80 those 54.25 41.85, respectively.The was reduced owing high number examinations performed work optimization.
Discussion about the impact of international harmonization higher-level patent protection in public health sector less developed countries just started to take place after so-called Doha Declaration. This paper advocates a more intense discussion on patents, highlighting not only that estimates benefits and losses resulting from greater have been negligent toward loss monopoly result but especially fact they do into account raise costs wealthy results this tendency harmonize.
Discussion about the impact of international harmonization higher-level patent protection in public health sector less developed countries just started to take place after so-called Doha Declaration. This paper advocates a more intense discussion on patents, highlighting not only that estimates benefits and losses resulting from greater have been negligent toward loss monopoly result but especially fact they do into account raise costs wealthy results this tendency harmonize.
Background: In last years, few attention has given to the patient's prediagnostic costs when evaluating introduction of new technologies for tuberculosis (TB) and in this context, study evaluated cost-effectiveness incurred with TB diagnosis comparing Bactec TM MGIT 960 system (MGIT) Löwestein–Jensen (LJ) culture a health center university hospital, Rio de Janeiro City, Brazil. Methods: Patient's mean were during process based on time days adoption appropriate clinical anti-TB treatment two...