- Pregnancy and preeclampsia studies
- Congenital Heart Disease Studies
- Prenatal Screening and Diagnostics
- Preterm Birth and Chorioamnionitis
- Cardiovascular Function and Risk Factors
- Fetal and Pediatric Neurological Disorders
- Gestational Diabetes Research and Management
- Pregnancy-related medical research
- Neonatal Respiratory Health Research
- Congenital Anomalies and Fetal Surgery
- Urological Disorders and Treatments
- Birth, Development, and Health
- Congenital Diaphragmatic Hernia Studies
- Cardiac Arrhythmias and Treatments
- Cardiovascular Issues in Pregnancy
- Cardiovascular Health and Disease Prevention
- HIV-related health complications and treatments
- Ectopic Pregnancy Diagnosis and Management
- Pelvic floor disorders treatments
- Phonocardiography and Auscultation Techniques
- Tumors and Oncological Cases
- Cardiac Valve Diseases and Treatments
- Bone fractures and treatments
- Neonatal and fetal brain pathology
- Cerebrovascular and Carotid Artery Diseases
University Hospital Münster
2014-2023
Klinik für Frauenheilkunde
2012-2019
Medical University of Vienna
2016-2019
University of Münster
2011-2019
Universitätsklinik für Frauenheilkunde und Geburtshilfe
2018
St Anna Children's Hospital
2015
Klinik für Schlafmedizin
2014
Abstract Objective: The aim of the study was to assess cervical strain pattern by an ultrasound elastography cervix examination and determine its association with preterm delivery. Methods: In this study, 30 cases resulting in birth gestational age-matched controls were included. A vaginal length measurement performed. We calculated four ratios (SR1–SR4) regions interest (ROIs) arranged pairs different positions on anterior lip. correlated outcome spontaneous inter-observer intra-observer...
To evaluate cervical elastography strain pattern as a predictive marker for spontaneous preterm delivery (SPTD). In this case-control study length (CL) and elastographic data (strain ratio, index, score) were acquired from 335 pregnant women (20th - 34th week of gestation) by transvaginal ultrasound. Data 50 deliveries compared with 285 normal controls. Strain ratio index calculated placing two regions interest (ROIs) in parallel on the anterior lip. The was determined dividing higher value...
Abstract Background The purpose of our study was to quantify the fetal myocardial function in pregnant women with diabetic diseases (FDM) and normal controls (FC) using speckle tracking echocardiography (STE). Methods In this prospective study, strain dyssynchrony were analyzed STE a transversal four-chamber view 180 fetuses (53 FDM, 127 FC) between 19 39 weeks gestation. measurements global segmental longitudinal both chambers (2C) single left chamber (1C) executed offline via QLab 10.5...
To determine whether certain rheumatic diseases will affect the fetal thymus diameter when compared to uncomplicated singleton pregnancies. Additionally, we created a reference chart for size in healthy pregnancies from 19 37 weeks of gestation.Sonographic was retrospectively evaluated 190 pregnant women, and 84 mothers suffering systemic lupus erythematosus, antiphospholipid syndrome (APS), or Sjögren's between gestation. These fetuses were matched one-to-one gestational age with control...
Abstract Purpose: To evaluate longitudinal mechanical dyssynchrony in normally grown fetuses by speckle tracking echocardiography (STE) and to compare fetal growth restriction (FGR) with normal controls. Materials methods: A prospective study was performed on 30 FGR 62 fetuses, including controls matched gestational age, using STE a transversal four-chamber view. Data analysis carried out high frame rate of about 175 frames/s. Dyssynchrony analyzed offline QLab 9 (Philips Medical Systems,...
Abstract Objective To reveal the effect of a maternal human immunodeficiency virus (HIV) infection on fetal thymus size. Methods The sonographic size was measured retrospectively in 105 pregnancies with HIV and 615 uncomplicated singleton pregnancies. anteroposterior thymic intrathoracic mediastinal diameter were determined three-vessel view their quotient, thymic-thoracic ratio (TT ratio), calculated. study group subdivided into three groups by viral load date ultrasound (<50 cop./mL,...
Abstract Objective: The aim of this study was to compare transabdominal chorionic villus sampling, transcervical sampling and amniocentesis with respect their total fetal loss rates. Methods: We retrospectively evaluated procedures invasive prenatal testing performed during a 14-year period (2001–2014) including 936 1051 samplings, which 405 cases were executed transabdominally 646 transcervically. Only singleton pregnancies before 24 weeks 0 days gestation where the pregnancy outcome known...
Abstract Objective: To evaluate segmental left (LV-S) and right (RV-S) ventricular strain as well longitudinal mechanical myocardial dyssynchrony a time difference between peaks in of both ventricles fetuses (two-chamber-dyssynchrony, 2C-DYS) using speckle tracking echocardiography (STE). The aim our study was to the influence data acquisition on results STE measurement different ultrasound probes. Methods: We prospectively recorded cardiac cycles four-chamber views 56 normal with three...
<b><i>Introduction:</i></b> The purpose was to compare thymus size measured during second trimester screening of fetuses who were subsequently small for gestational age at birth (weight below 10th percentile, SGA group) with normal weight (control group). We hypothesized that measuring the fetal thymic-thoracic ratio (TT-ratio) might help predict low weight. <b><i>Methods:</i></b> Using three-vessel view echocardiograms from our archives, we...
Abstract Objective To compare the adrenal gland size of fetal growth restricted (FGR) and normal control fetuses. Study design In this prospective study 63 FGR fetuses 343 controls was measured between 20 41 weeks gestation. The total width medulla were in a new standardized transversal plane. cortex calculated ratio (adrenal ratio) compared both groups. Results mean higher comparison to (P<0.001; P=0.036, respectively). correlated positively with gestational age (control group:...
Abstract Objective: To compare the fetal brain structures assessed in routine sonographic scans during second and third trimesters diabetic normal pregnancies. Methods: In this retrospective study, we measured head circumference (HC), transversal diameter of cerebellum (TCD) sizes cisterna magna (CM), cavum septi pellucidi (CSP) lateral ventricles (LV) stored between 20 41 weeks gestation. We compared 231 fetuses mothers (diabetic group) to pregnancies (control matched by gestational age....
Abstract Objective To compare myocardial strain and mechanical dyssynchrony in fetuses with congenital heart disease (CHD) to normal controls using speckle tracking echocardiography (STE). Methods In this comparative cross-sectional study 23 CHD 105 between 19 41 weeks of gestation were assessed STE. The STE sample box was placed over the myocardium both ventricles. parameters interest included segmental left (LV-S) right lateral ventricle wall (RV-S) global ventricular chambers (2C-S)....
Background The aim of this study was to compare the adrenal gland size fetuses women with gestational diabetes mellitus (GDM) that healthy control fetuses. Methods This prospective cross-sectional included measurements 62 GDM (GDM group) and 370 normal controls (control between 19th 41st week gestation. A standardized transversal plane used measure total width medulla width. cortex an ratio (total width/medulla width) were calculated from these data. Adrenal adjusted gestation compared two...
Abstract Background The aim of this study was to compare Philips and TomTec two-dimensional speckle tracking echocardiography (2D-STE) software measurements strain dyssynchrony values in healthy fetuses. Methods This an explorative observational which the echocardiographic data 93 fetuses between 20 th 38 week gestation were determined from a four-chamber view using 2D tracking. global segmental longitudinal both ventricles, inter-ventricular left intra-ventricular analyzed QLab version 10.8...
To assess the influence of frame rate settings on longitudinal strain (LS) and mechanical synchrony (SYN) values in Speckle Tracking Echocardiography (STE) healthy fetuses.In this prospective study, we collected transversal or apical four-chamber-views 121 fetuses between 20 38 weeks gestation using three different (FR) (≥ 110, 100 ± 10, 60 10 frames per second). We assessed segmental global LS both ventricles (2C) left ventricle (LV) offline with QLab 10.8 (Philips Medical Systems, Andover,...
Abstract Objective To assess whether fetal brain structures routinely measured during the second and third trimester ultrasound scans, particularly width of cavum septi pellucidi (CSP), differ between fetuses small for gestational age (SGA), very (VSGA) normal controls. Methods In this retrospective study, we examined standard measurements 116 VSGA, 131 SGA 136 controls including head circumference (HC), transversal diameter cerebellum (TCD), sizes lateral ventricle (LV) cisterna magna (CM)...
The Doppler assessment of the middle cerebral artery (MCA) has a central role in monitoring high-risk pregnancies. objective this study was to investigate importance preset settings for measurement peak systolic velocity (PSV) and pulsatility index (PI) MCA.The PI PSV MCA were determined prospectively 350 healthy fetuses between 19 42 weeks pregnancy. first (MCA.S) performed with conventional second (MCA.O) an optimized setting maximum achievable frame rate. For MCA.O measurement, width...
<b><i>Background:</i></b> The examination of the fetal ear is a promising but still challenging approach in prenatal diagnosis. <b><i>Objectives:</i></b> This study investigated novel length/width ratio based on anatomical landmarks. Additionally, we compared different 3D ultrasound surface rendering modes regarding their potential to depict detailed structures outer ear. <b><i>Method:</i></b> We measured both length and...
Abstract Background The aim of this study was to compare transabdominal and transcervical chorionic villus sampling (CVS) as well amniocentesis (AC) with respect their rates premature delivery fetal growth restriction. Methods We retrospectively evaluated the mentioned procedures invasive prenatal testing performed in a single center between 2001 2016. Seven hundred ninety-nine cases AC 719 CVS were included, which 400 transvaginally. Only singleton pregnancies normal karyotype after 24 + 0...