Karthikeyan Ramalingam

ORCID: 0000-0003-1921-8336
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About
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Research Areas
  • Oral and Maxillofacial Pathology
  • Oral Health Pathology and Treatment
  • Parasite Biology and Host Interactions
  • Head and Neck Cancer Studies
  • Dental Radiography and Imaging
  • dental development and anomalies
  • Dental Implant Techniques and Outcomes
  • Forensic Anthropology and Bioarchaeology Studies
  • Salivary Gland Tumors Diagnosis and Treatment
  • Bone Tumor Diagnosis and Treatments
  • Environmental Toxicology and Ecotoxicology
  • Tumors and Oncological Cases
  • Oral microbiology and periodontitis research
  • Head and Neck Surgical Oncology
  • Dental Health and Care Utilization
  • Dental materials and restorations
  • Oral health in cancer treatment
  • Oral and gingival health research
  • Orthodontics and Dentofacial Orthopedics
  • Helminth infection and control
  • Dental Research and COVID-19
  • Bone and Dental Protein Studies
  • Salivary Gland Disorders and Functions
  • Clinical Laboratory Practices and Quality Control
  • Facial Nerve Paralysis Treatment and Research

Saveetha University
2007-2025

G Pulla Reddy Dental College & Hospital
2025

Rajalakshmi Engineering College
2024

Haldia Institute of Technology
2023-2024

Mahatma Gandhi Dental College & Hospital
2023-2024

Centre for Global Health Research
2024

Sebha University
2013-2024

Kamineni Institute of Dental Sciences
2012-2024

Universal College of Medical Sciences
2023-2024

Institute of Medical Sciences
2023-2024

<ns4:p>Introduction Globally, oral cancer is the 15<ns4:sup>th</ns4:sup> deadliest among humans. Diverse health education interventions have played a very significant role in prevention of cancer. Of these interventions, digital especially mhealth-driven been largely underutilized. So far, only two known educative mobile applications (MHAs) for exits; unfortunately, are not comprehensive and inclusive diverse populations. There need more MHA that can be used to educate public about...

10.12688/f1000research.159649.1 preprint EN cc-by F1000Research 2025-01-13

Abstract Background and introduction Statisticians rank oral lip cancer sixth in global mortality at 10.2%. Mouth opening swallowing are challenging. Hence, most patients only report later stages. They worry about surviving receiving therapy. Oral severely affects QOL. QOL is affected by risk factors, disease site, treatment. Using patient questionnaires, we use light gradient Boost Tree classifiers to predict life quality. Methods DIAS records were used for 111 patients. The European...

10.1186/s12903-024-04050-x article EN cc-by BMC Oral Health 2024-03-19

This study was designed to compare inorganic salivary calcium, phosphate, flow rate and pH of un-stimulated saliva oral hygiene healthy subjects, patients with periodontitis dental caries correlate calcium level the number intact teeth.The present consisted 90 aged between 18 55 years were divided into three groups, periodontitis, controls. Oral index-simplified, probing pocket depth, clinical attachment teeth present, active carious lesions recorded. Salivary recorded subjected biochemical...

10.4103/0972-124x.118316 article EN cc-by-nc-sa Journal of Indian Society of Periodontology 2013-01-01

Artificial intelligence in oncology has gained a lot of interest recent years. Early detection Oral squamous cell carcinoma (OSCC) is crucial for early management to attain better prognosis and overall survival. Machine learning (ML) also been used oral cancer studies explore the discrimination between clinically normal cancer.A dataset comprising 360 clinical intra-oral images OSCC, Potentially Malignant Disorders (OPMDs) healthy mucosa were used. Clinicians trained machine model with...

10.7759/cureus.44018 article EN Cureus 2023-08-24

Aim: The present study explored the anti-inflammatory, antimicrobial, antioxidant, and cytotoxic effects of a combination chitosan thiocolchicoside lauric acid (CTLA) nanogel. Materials methods: A nanogel formulation was developed tested for potential applications. antimicrobial activity assessed using well diffusion method, while antioxidant evaluated 2,2-diphenyl-1-picryl hydrazyl (DPPH) free radical scavenging assay hydrogen peroxide (H2O2) methods. anti-inflammatory determined through...

10.7759/cureus.46003 article EN Cureus 2023-09-26

Abstract The present study explored the anticancer activity of a Chitosan-based nanogel incorporating thiocolchicoside and lauric acid (CTL) against oral cancer cell lines (KB-1). Cell viability, AO/EtBr dual staining cycle analysis were done to evaluate impact CTL on cells. Real-time PCR was performed analyze proapoptotic antiapoptotic gene expression in CTL-treated KB-1 Further, molecular docking conducted explore interaction our key ingredient, its binding affinities. demonstrated potent...

10.1038/s41598-024-60046-1 article EN cc-by Scientific Reports 2024-04-23

Background: As oral cancer remains a major worldwide health concern, sophisticated diagnostic tools are needed to aid in early diagnosis. Non-invasive methods like exfoliative cytology, albeit with the help of artificial intelligence (AI), have drawn additional interest. Aim: The study aimed harness power machine learning algorithms for automated analysis nuclear parameters cytology. Further, two different AI systems, namely convoluted neural networks (CNN) and support vector (SVM), were...

10.7759/cureus.58744 article EN Cureus 2024-04-22

Aim This study aims to examine five mandibular parameters: coronoid ramus height, condylar projective minimum breadth, and gonial angle, using orthopantomography (OPG). Introduction The mandible, a crucial part of the human skull, demonstrates sexual dimorphism, which makes it an important tool for determining sex in forensic anthropological investigations. Its form structure are relatively resistant significant changes after death. Among all skeletal components, mandible stands out as...

10.7759/cureus.55788 article EN Cureus 2024-03-08

Aim and objective This study aims to assess the accuracy of gender estimation using gonial antegonial angles determine given samples angles. Introduction An essential component human skull, mandible, exhibits sexual dimorphism, making it a valuable tool in forensic anthropological investigations for detecting sex. procedure can be especially difficult situations where there are large numbers casualties, natural disasters, or widely dispersed remains. The mandible is an accurate indicator age...

10.7759/cureus.56603 article EN Cureus 2024-03-20

To investigate the cytocompatibility effect and wound healing activity of chitosan thiocolchicoside lauric acid (CTL) nanogel using human gingival fibroblast (hGF) cells.hGF cells were established from tissue as per standard cell isolation protocol. The was assessed an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide) assay. A scratch assay performed to assess wound-healing potential CTL nanogel. For nuclear morphological changes analysis, acridine orange staining used in...

10.7759/cureus.43727 article EN Cureus 2023-08-18

Background: The pressing need for precise, quick, and affordable detection of diverse biomolecules has led to notable developments in the realm biosensors. Quercetin, a biomolecule rich flavonoids predominantly found our diet, is sensed by electrochemical method. properties show remarkable improvement when Mn2O3 (MO) doped with cobalt (Co). Aim: This study aimed investigate sensing quercetin using Co-doped MO Materials methods: nanospheres were prepared hydrothermal crystal structure...

10.7759/cureus.56665 article EN Cureus 2024-03-21

Background Head and neck bone pathologies cover various conditions with diverse causes. Infections like osteomyelitis dental abscesses can spread to soft tissues bones, causing tissue death, inflammation, systemic effects. Benign malignant tumors develop from tissue, cartilage, or bone, posing challenges for diagnosis treatment. Studies on their prevalence in local populations are rare, obscuring our understanding of regional health dynamics. Aim In this study, we aimed assess the documented...

10.7759/cureus.60574 article EN Cureus 2024-05-18

Background Natural compounds and biomaterials, such as nanohydrogels, have gained interest due to their biocompatibility tissue regeneration potential. A novel nanohydrogel was prepared by employing Tridax procumbens, a traditional plant with anti-inflammatory properties chitosan nanoparticles natural bioadhesive potent antimicrobial antioxidant effects dopamine, which has been shown regulate angiogenesis influence cell growth. The objective of this study examine how human gingival...

10.7759/cureus.62819 article EN Cureus 2024-06-21

The clear cell variant of oral squamous carcinoma (CCSCC) is an uncommon aggressive lesion found in the cavity. Limited cases CCSCC have been documented literature. This report discusses a 38-year-old female presenting with non-healing ulcer right retromolar region, accompanied by pain and discomfort. Histopathological analysis revealed sheets islands severely dysplastic epithelial cells cytoplasm keratin pearls within connective tissue, indicating rare carcinoma. Various differential...

10.7759/cureus.77450 article EN Cureus 2025-01-14

Tooth extraction, a common dental procedure, is often accompanied by pain, trismus, and swelling due to alveolitis caused oral bacteria. Doxycycline prescribed alleviate infection improve socket healing, but its immediate absorption in the bloodstream makes treatment less effective at sites. This emphasizes importance of drug delivery system gradually slow release wound site increase bioavailability make over time. Silk fibroin (SF) - doxycycline hyclate (DH) hydrogel was developed...

10.1186/s12903-025-05568-4 article EN cc-by-nc-nd BMC Oral Health 2025-02-01

Orthodontic treatment involves the use of bite turbos that are frequently utilized in orthodontic therapy to disocclude lower and upper teeth achieve adequate alignment leveling. This occurs due excessive intrusive forces which led resorption roots. study aimed quantify amount apical root molar region caused by using orthopantomograms (OPGs). The involved 30 OPGs pertaining patients, each before after therapy. group patients for whom were placed mandibular a minimum 4 months during...

10.18231/j.jco.2025.006 article EN cc-by-nc-sa Journal of Contemporary Orthodontics 2025-02-08
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