A5101506253- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Renal Diseases and Glomerulopathies
- Cancer-related gene regulation
- Renal cell carcinoma treatment
- Multiple and Secondary Primary Cancers
- Peptidase Inhibition and Analysis
- Epigenetics and DNA Methylation
- Global Cancer Incidence and Screening
- Breast Cancer Treatment Studies
- Cancer Immunotherapy and Biomarkers
Gaozhou People's Hospital
2021-2025
Jiaying University
2020
Abnormal m6A methylation plays a significant role in cancer progression. Increasingly, researchers have focused on developing lncRNA signatures to evaluate the prognosis of patients. The specific function m6A-related lncRNAs bladder patients and immune microenvironment remains elusive. Herein, we performed comprehensive analysis prognostic values their association with using TCGA dataset. A total 9 were dramatically correlated overall survival outcomes cancer. Two molecular subtypes (cluster...
Background: There is increasing evidence of the epigenetic regulation immune response in cancer. However, specific functions and mechanisms RNA N6-methyladenosine (m6A) modification cell infiltration hepatocellular carcinoma (HCC) tumor microenvironment (TME) unknown. Methods: We systematically analyzed m6A-modification patterns 371 HCC samples based on 23 m6A regulators, determined their correlation with TME cell-infiltrating characteristics. Principal-component analysis algorithms was used...
Background A second primary malignant tumor is one of the most important factors affecting long-term survival young women with breast cancer (YWBC). As main treatments for YWBC patients, postoperative radiotherapy (PORT) may increase risk malignancy (SPM). Methods Machine learning components, including ridge regression, XGBoost, k-nearest neighbor, light gradient boosting machine, logistic support vector neural network, and random forest, were used to construct a predictive model identify...