Paul F. Smith

ORCID: 0000-0003-1961-7118
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About
Contact & Profiles
Research Areas
  • Vestibular and auditory disorders
  • Hearing, Cochlea, Tinnitus, Genetics
  • Neuroscience and Neuropharmacology Research
  • Glaucoma and retinal disorders
  • Olfactory and Sensory Function Studies
  • Cannabis and Cannabinoid Research
  • Neuroscience of respiration and sleep
  • Sleep and Wakefulness Research
  • Memory and Neural Mechanisms
  • Ophthalmology and Eye Disorders
  • Hearing Loss and Rehabilitation
  • Noise Effects and Management
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Biochemical Analysis and Sensing Techniques
  • Neurotransmitter Receptor Influence on Behavior
  • Nitric Oxide and Endothelin Effects
  • Underwater Acoustics Research
  • Marine animal studies overview
  • Ocular Surface and Contact Lens
  • Neurogenesis and neuroplasticity mechanisms
  • Retinal Development and Disorders
  • Visual perception and processing mechanisms
  • Stress Responses and Cortisol
  • Underwater Vehicles and Communication Systems
  • Cerebral Venous Sinus Thrombosis

University of Auckland
2016-2025

University of Otago
2016-2025

Brain Research New Zealand
2015-2024

Naval Postgraduate School
2024

University of Nottingham Malaysia Campus
2021

Royal Alexandra Children's Hospital
2021

Biostatistical Consulting (United States)
2021

Wake Forest University
2021

Para La Tierra
2019

University of Warwick
2018

The human hippocampal formation plays a crucial role in various aspects of memory processing. Most literature on the hippocampus stresses its non-spatial functions, but older work rodents and some other species emphasized spatial learning as well. A few studies also point to direct relation between size, navigation memory. Conversely, importance vestibular system for was until now convincingly demonstrated only animals. Using magnetic resonance imaging volumetry, we found that patients (n =...

10.1093/brain/awh617 article EN Brain 2005-09-01

The hippocampus is thought to be important for spatial representation processes that depend on the integration of both self-movement and allocentric cues. vestibular system a particularly source information may contribute this representation. To test hypothesis provides hippocampus, rats were given either bilateral labyrinthectomy (n = 6) or sham surgery 6), at least 60 d after hippocampal CA1 neurons recorded extracellularly while animals foraged freely in an open arena. Recorded cells...

10.1523/jneurosci.23-16-06490.2003 article EN Journal of Neuroscience 2003-07-23

The light intensity-fusion frequency relationship of the goldfish electroretinogram follows Ferry-Porter law except at higher intensities. Maximum fusion increases with temperature thus contradicting results studies elsewhere on behavioral responses in sunfish.

10.1126/science.140.3567.662 article EN Science 1963-05-10

The vestibular (inner ear balance) system senses head movement and orientation in space. Vestibular sensory input plays a critical role spatial cognitive abilities such as memory navigation. function declines with age, recent studies have shown that age-related impairment is associated poorer skills healthy older adults. Moreover, disproportionately prevalent among individuals mild Alzheimer's disease, specifically cognitively-impaired who deficits disorientation difficulty driving. Indeed,...

10.1080/13607863.2019.1566813 article EN Aging & Mental Health 2019-01-29

The hippocampus has a major role in memory for spatial location. Theta is rhythmic hippocampal EEG oscillation that occurs at approximately 8 Hz during voluntary movement and may have some encoding information. We investigated whether, as part of this process, theta might be influenced by self-movement signals provided the vestibular system. effects bilateral peripheral lesions, made > or = 60 days prior to recording, were assessed freely moving rats. Power spectral analysis revealed...

10.1152/jn.00953.2005 article EN Journal of Neurophysiology 2006-06-13

For more than a decade, evidence from animal studies has suggested that damage to the vestibular system leads deficits in spatial navigation which are indicative of impaired learning and memory. More recently, direct emerged demonstrate humans with disorders exhibit range cognitive not just nature, but also include non-spatial functions such as object recognition Vestibular dysfunction been shown adversely affect attentional processes increased demands can worsen postural sway associated...

10.3233/ves-2005-15101 article EN Journal of Vestibular Research 2005-02-01
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