A5034464254- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer Treatment and Pharmacology
- Cardiac Health and Mental Health
- Heart Failure Treatment and Management
- Cardiovascular and exercise physiology
- Blood Pressure and Hypertension Studies
- Economic and Financial Impacts of Cancer
- Cardiac Ischemia and Reperfusion
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular Health and Disease Prevention
- HER2/EGFR in Cancer Research
- Drug-Induced Ocular Toxicity
- Cardiovascular Function and Risk Factors
- Medical and Agricultural Research Studies
- Polymer Nanocomposite Synthesis and Irradiation
- Healthcare Systems and Public Health
- Hydrogen's biological and therapeutic effects
- Phosphodiesterase function and regulation
- Human Health and Disease
- Cancer survivorship and care
National Medical Research Center of Cardiology
2023-2025
Research Medical Center
2021
.
Background: Patients having been treated for breast cancer (BC) are at increased risk of cardiovascular disease (CVD). Participation patients with high (CVR) in comprehensive cardiac rehabilitation programs seems to be a promising area prevention; however, present there is no understanding the scope need such Russia. Aim: To evaluate frequency CVDs and their factors, total CVR BC who have undergone cardiotoxic antitumor treatment determine development this patient category. Methods: This was...
Enhanced cancer treatment efficacy has resulted in a significant increase the number of survivors after cure malignant tumors. However, cardiovascular morbidity, including chronic heart failure, become leading cause death and decreased life expectancy among survivors. This is due, particular, to cardiotoxic effects anticancer drugs associated factors. Cardioprotective approaches aim reduce incidence severity cardiotoxicity through use cardioprotective agents (e.g., dexrazoxane), liposomal...
To evaluate the effect of Sacubitril/Valsartan (S/V) on functional status, systolic and diastolic function left ventricle (LV), tolerability therapy to determine predictors its effectiveness in patients with cancer therapy-related heart failure (СTRHF). Forty 58 [46; 65.5] years age HF associated anthracycline-containing were enrolled. Clinical examination, echocardiography, assessment potassium creatinine levels performed at baseline after 6 months S/V therapy. NYHA class (FC) improvement...
The article presents a clinical case of heart failure associated with the anthracycline-containing antitumor therapy in breast cancer patient an initially low risk developing cardiovascular complications.
Aim. To evaluate the drug implied to improve metabolic resistance stress (adaptogen), Qudesan®, on its influence cardiovascular system, psychological status and life quality of patients with average high risk in extreme climatic conditions (the summer heat). Material methods. We included 60 patients; for 30 those Qudesan® 40 gtts. qd was added standard therapy; other were controls. measured office BP, potassium sodium concentrations; malonic dialdehyde (MDA), superoxidedysmutase (SOD)...
The course of hypertension is often complicated by left ventricular hypertrophy (or hypertensive heart disease, HHD). main “corridor” natural HHD development failure with preserved ejection fraction (HFpEF). With HFpEF, the bioavailability natriuretic peptides (NP) significantly reduced, as a result which activity cGMP-PKG signaling pathway, plays key role in maintaining normal diastolic function, weakens. It possible to increase this pathway using neprilysin inhibitor sacubitril. In case...
<h3></h3> У больных раком молочной железы (РМЖ), получающих многокомпонентную противоопухолевую терапию, повышен риск развития сердечно-сосудистых заболеваний и их осложнений. Перспективным подходом снижения сердечно-сосудистого риска (ССР) у данной категории пациентов является участие в программах кардиореабилитации, основанных на регулярных физических тренировках. Как общей популяции, консультирование РМЖ по физической активности физическим нагрузкам (ФН) не находит широкого применения...