A5004193446- Analytical Chemistry and Chromatography
- Chemical Reaction Mechanisms
- Chemical Reactions and Isotopes
- Advanced Chemical Physics Studies
- Mass Spectrometry Techniques and Applications
- Asymmetric Synthesis and Catalysis
- Inorganic and Organometallic Chemistry
- Chemical Synthesis and Reactions
- Essential Oils and Antimicrobial Activity
- Molecular Spectroscopy and Structure
- Molecular Junctions and Nanostructures
- Phytochemistry and Biological Activities
- Electrochemical Analysis and Applications
- Fluorine in Organic Chemistry
- Organic and Inorganic Chemical Reactions
- Natural product bioactivities and synthesis
- Catalysis for Biomass Conversion
- Microbial Metabolic Engineering and Bioproduction
- Ionic liquids properties and applications
- Chemical Thermodynamics and Molecular Structure
- Enzyme Structure and Function
- Biofuel production and bioconversion
- Organic Chemistry Cycloaddition Reactions
- Synthetic Organic Chemistry Methods
- Spectroscopy and Quantum Chemical Studies
Sapienza University of Rome
1993-2021
Università di Camerino
1982-1983
Forschungszentrum Jülich
1977
Istituto di Farmacologia Traslazionale
1975
In this work, essential oils (EOs) and hydrolates (Hys) of Rosmarinus officinalis L. Lavandula angustifolia Mill., grown in Tuscany (Italy), were studied to describe their chemical composition biological activities. The aromatic profile the EOs liquid phase was carried out by gas chromatography–mass spectrometry (GC–MS), while volatile vapor Hys performed headspace (HS)/GC–MS. obtained results show that monoterpene hydrocarbons (71.5% 89.5%) main compounds, followed oxygenated monoterpenes...
In this study, the chemical composition of vapor and liquid phase Pinus cembra L., mugo Turra, Picea abies Abies Alba M. needles essential oils (EOs) was investigated by Headspace-Gas Chromatography/Mass Spectrometry (HS-GC/MS). examined EOs, a total twenty-eight components were identified, most which belong to monoterpenes family. α-Pinene (16.6–44.0%), β-pinene (7.5–44.7%), limonene (9.5–32.5%), γ-terpinene (0.3–19.7%) abundant phase. Such major compounds also detected in all α-pinene...
Essential oils from Lavandula genus and the obtained hybrids are widely used for different purposes such as perfume production in cosmetic field its biological properties. This is first study on liquid vapour phase of × intermedia “Grosso” essential oil grown Lazio Region, Italy, investigated using headspace coupled to gas chromatography mass spectrometry (HS-GC/MS). The results showed most abundant components were linalool linalyl acetate, followed by 1,8-cineole terpinen-4-ol, while...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSubstrate selectivity and orientation in aromatic Substitution by molecular fluorineF. Cacace, P. Giacomello, A. WolfCite this: J. Am. Chem. Soc. 1980, 102, 10, 3511–3515Publication Date (Print):May 1, 1980Publication History Published online1 May 2002Published inissue 1 1980https://pubs.acs.org/doi/10.1021/ja00530a034https://doi.org/10.1021/ja00530a034research-articleACS PublicationsRequest reuse permissionsArticle...
The immobilization of ferrocene's amino derivatives onto carboxyl-functionalized multiwalled carbon nanotubes (MWCNTs−COOH) electrodes has been carried out to test the ability ion reactive landing procedure realize chemically modified electrodes. ionic species involved in were structurally and energetically characterized by joint application collisionally induced dissociation mass spectrometry theoretical calculations. Furthermore, surface was analyzed spectroscopic voltammetric techniques...
Schinus molle (L.) is a dioecious plant of the Anacardiaceae family, originating in South America and currently widespread many regions throughout world. In this work leaf extracts derived low-pressure column chromatography (LPCC) fractions S. L. male female plants were investigated for antimicrobial activity. Leaf tested on microbes Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Candida albicans Bacillus subtilis. Furthermore, showing activity...
Recent scientific investigations have reported a number of essential oils to interfere with intracellular signalling pathways and induce apoptosis in different cancer cell types. In this paper, Lavandin Essential Oil (LEO), natural sterile hybrid obtained by cross-breeding L. angustifolia × latifolia, was tested on human leukaemia cells (HL60). Based the MTT results, reduced viability HL60 further investigated determine whether death related apoptotic process. treated for 24 h LEO were...
Lavandin essential oil (LEO), a natural sterile hybrid obtained by crossbreeding L. angustifolia × latifolia, is mainly composed active components belonging to the family of terpenes endowed with relevant anti-proliferative activity, which can be enhanced proper application nanotechnology. In particular, this study reports chemical characterization and screening activity on different human cell lines pure nano-formulated lavandin (EO). LEO its formulation (NanoLEO) were analyzed HS/GC-MS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCompetitive condensation and proton-transfer processes in the reaction of tert-C4H9+ ions with ammonia gaseous systems at atmospheric pressureMarina Attina, Fulvio Cacace, Pierluigi Giacomello, Maurizio SperanzaCite this: J. Am. Chem. Soc. 1980, 102, 22, 6896–6898Publication Date (Print):October 15, 1980Publication History Published online1 May 2002Published inissue 15 October...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas-phase reaction of tert-butyl ions with arenes. Remarkable selectivity a gaseous, charged electrophileFulvio. Cacace and Pierluigi. GiacomelloCite this: J. Am. Chem. Soc. 1973, 95, 18, 5851–5856Publication Date (Print):September 1, 1973Publication History Published online1 May 2002Published inissue 1 September 1973https://pubs.acs.org/doi/10.1021/ja00799a002https://doi.org/10.1021/ja00799a002research-articleACS PublicationsRequest reuse...
Understanding on a molecular level the acid-catalysed decomposition of sugar monomers from hemicellulose and cellulose (e.g. glucose, xylose), main constituent lignocellulosic biomass is very important to increase selectivity reaction yields in solution, key steps for development sustainable renewable industry. In this work we reported gas-phase study performed by electrospray triple quadrupole mass spectrometry dehydration mechanism d-glucose. gas phase, reactant ions corresponding...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAromatic substitution in the gas phase. Alkylation of xylenes and toluene by isopropyl(1+) ionsMarina Attina, Fulvio Cacace, Giovanna Ciranni, Pierluigi GiacomelloCite this: J. Am. Chem. Soc. 1977, 99, 8, 2611–2615Publication Date (Print):April 1, 1977Publication History Published online1 May 2002Published inissue 1 April 1977https://pubs.acs.org/doi/10.1021/ja00450a034https://doi.org/10.1021/ja00450a034research-articleACS PublicationsRequest reuse...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAromatic substitution in the gas phase. Alkylation of arenes by gaseous C4H9+ cationsFulvio Cacace, Giovanna Ciranni, and Pierluigi GiacomelloCite this: J. Am. Chem. Soc. 1981, 103, 6, 1513–1516Publication Date (Print):March 1, 1981Publication History Published online1 May 2002Published inissue 1 March 1981https://pubs.acs.org/doi/10.1021/ja00396a035https://doi.org/10.1021/ja00396a035research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas-phase alkylation of xylenes by tert-butyl(1+) ionsPierluigi Giacomello and Fulvio CacaceCite this: J. Am. Chem. Soc. 1976, 98, 7, 1823–1828Publication Date (Print):March 1, 1976Publication History Published online1 May 2002Published inissue 1 March 1976https://pubs.acs.org/doi/10.1021/ja00423a029https://doi.org/10.1021/ja00423a029research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations14LEARN ABOUT THESE...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas-Phase Protonation of Allene and Propyne. Remarkably Selective Formation 2-Propenyl IonsSimonetta Fornarini, Maurizio Speranza, Marina Attina, Fulvio Cacace, Pierluigi GiacomelloCite this: J. Am. Chem. Soc. 1984, 106, 9, 2498–2501Publication Date (Print):May 1, 1984Publication History Published online14 August 2003Published inissue 1 May 1984https://pubs.acs.org/doi/10.1021/ja00321a600https://doi.org/10.1021/ja00321a600research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDoes the cyclohexyl cation exist in dilute gas state? Direct evidence from a radiolytic studyMarina Attina, Fulvio Cacace, and Pierluigi GiacomelloCite this: J. Am. Chem. Soc. 1981, 103, 16, 4711–4714Publication Date (Print):August 1, 1981Publication History Published online1 May 2002Published inissue 1 August 1981https://doi.org/10.1021/ja00406a008RIGHTS & PERMISSIONSArticle Views71Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAromatic substitution in the gas phase. A comparative study of alkylation benzene and toluene with C3H7+ ions from protonation cyclopropane propeneMarina Attina, Fulvio Cacace, Pierluigi GiacomelloCite this: J. Am. Chem. Soc. 1980, 102, 14, 4768–4772Publication Date (Print):July 1, 1980Publication History Published online1 May 2002Published inissue 1 July...
The mechanism of reactions occurring in solution can be investigated also the gas phase by suited mass spectrometric techniques, which allow to highlight fundamental mechanistic features independent influence medium and clarifying controversial hypotheses proposed studies. In this work, we report a gas-phase study performed electrospray triple stage quadrupole spectrometry (ESI-TSQ/MS) on dehydration D-xylose, leading mainly formation 2-furaldehyde (2-FA). It is generally known carbohydrate...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactivity and selectivity of the methoxycarbonyl cation in gas-phase electrophilic aromatic substitutionPierluigi Giacomello Federico PepiCite this: J. Phys. Chem. 1993, 97, 17, 4421–4426Publication Date (Print):April 1, 1993Publication History Published online1 May 2002Published inissue 1 April 1993https://pubs.acs.org/doi/10.1021/j100119a029https://doi.org/10.1021/j100119a029research-articleACS PublicationsRequest reuse permissionsArticle...
A nuclear technique based on the spontaneous decay of tritiated precursors that allows generation free carbonium ions exactly same nature in different environments, has been exploited a comparative study aromatic alkylation by CT3+ ions, both gas phase at various pressures and liquid phase. The differences between reactivity pattern methyl cation two environments can be essentially reduced to much greater efficiency collisional stabilization condensed phase, allowing larger fraction excited...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAromatic substitution in the liquid phase by bona fide free methyl cations. Alkylation of benzene and tolueneFulvio Cacace Pierluigi GiacomelloCite this: J. Am. Chem. Soc. 1977, 99, 16, 5477–5478Publication Date (Print):August 1, 1977Publication History Published online1 May 2002Published inissue 1 August 1977https://pubs.acs.org/doi/10.1021/ja00458a040https://doi.org/10.1021/ja00458a040research-articleACS PublicationsRequest reuse...