A5061296890- Asthma and respiratory diseases
- Autism Spectrum Disorder Research
- Immune Cell Function and Interaction
- Adenosine and Purinergic Signaling
- Psoriasis: Treatment and Pathogenesis
- Cytokine Signaling Pathways and Interactions
- Tryptophan and brain disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- T-cell and B-cell Immunology
- Immune Response and Inflammation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Dermatology and Skin Diseases
- Mast cells and histamine
- Genetics and Neurodevelopmental Disorders
- IL-33, ST2, and ILC Pathways
- Nitric Oxide and Endothelin Effects
- Antimicrobial Peptides and Activities
- Systemic Lupus Erythematosus Research
- RNA Interference and Gene Delivery
- Immunodeficiency and Autoimmune Disorders
- Vitamin C and Antioxidants Research
- Pediatric health and respiratory diseases
- NF-κB Signaling Pathways
- Epigenetics and DNA Methylation
King Saud University
2016-2025
New York Medical College
2024-2025
Cleveland Clinic
2023-2024
University of Tulsa
2021-2024
Aga Khan University
2024
University of Engineering and Technology Lahore
2023
Helwan University
2023
Osmania General Hospital
2022
University of Agriculture Faisalabad
2013-2022
Guru Gobind Singh Medical College and Hospital
2022
Graphene oxide offers a promising opportunity to fabricate highly efficient and pressure-endurable membranes in terms of water permeability while demonstrating high level solute rejection. However, achieving higher permeance with an excellent separation capability is still challenging. Herein, we report class graphene oxide-lignin biopolymer (GOLB) for the first time prepared by functionalizing GO nanosheets lignin extracted from plant pulp. Lignin most abundant, green, low-cost,...
The pathogenesis of several neuropsychiatric disorders, including anxiety and depression, has been linked to oxidative stress, in part via alterations cyclic nucleotide signaling. Phosphodiesterase-2 (PDE2), which regulates cGMP cAMP signaling, may affect anxiety-related behavior through reduction stress. present study evaluated the effects stress on assessed anxiolytic PDE2 inhibitor Bay 60-7550 [(2-(3,4-dimethoxybenzyl)-7-{(1R)-1-[(1R)-1-hydroxyethyl]-4-phenylbutyl}-5-methyl...
This open-label, randomized phase II trial assessed efficacy and tolerability of two low-dose regimens subcutaneous (SC) decitabine in patients with low- or intermediate-1-risk myelodysplastic syndrome (MDS).Patients received 20 mg/m(2) SC per day for 3 consecutive days on 1, 2, every 28 (schedule A) once 7 8, 15 B) up to 1 year. Primary end point was overall improvement rate (OIR: complete remission [CR], partial [PR], marrow CR [mCR], hematologic [HI]). Secondary points were HI,...
Asparagine-modified GO membranes are prepared to efficiently reject rhodamine B dye up 99.9%, along with a water permeability of ∼1740 ± 10 L m −2 h −1 bar . Further, such stable in 34 days.
In this work, we for the first time use a supramolecular compound (p-tetrasulfonato calix[4]arene) as functionalizing agent to modify graphene oxide (GO) nanosheets and prepare unique class of GO/p-TSC4 lamellar membranes, which are then successfully applied removal toxic environmental contaminants from wastewater. The membrane (320 ± 20 nm) exhibits outstanding separation efficiency different organic dyes, e.g., crystal violet, rhodamine B, eosin Y, congo red, methylene blue, with superfast...
Lung and colon cancers are among the leading causes of human mortality morbidity. Early diagnostic work up these diseases include radiography, ultrasound, magnetic resonance imaging, computed tomography. Certain blood tumor markers for carcinoma lung also aid in diagnosis. Despite lab histopathology remains gold standard, which provides cell-level images tissue under examination. To read images, a histopathologist spends large amount time. Furthermore, using conventional methods involve...
Mica-modified graphene oxide membranes exhibit high water permeability with 100% rejection for tannic acid and bovine serum albumin.
We have shown that proteinase-activated receptor-2 (PAR(2)) activation in the airways leads to allergic sensitization concomitantly inhaled Ags, thus implicating PAR(2) pathogenesis of asthma. Many aeroallergens with proteinase activity activate PAR(2). To study role aeroallergens, we developed a murine model mucosal cockroach proteins. hypothesized by natural allergens serine plays an important sensitization. Cockroach extract (CE) was administered BALB/c mice intranasally on five...