- Renal Transplantation Outcomes and Treatments
- COVID-19 Clinical Research Studies
- Organ Transplantation Techniques and Outcomes
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Neurological Complications and Syndromes
- Cytomegalovirus and herpesvirus research
- COVID-19 and healthcare impacts
- Organ Donation and Transplantation
- Multiple Myeloma Research and Treatments
- COVID-19 Impact on Reproduction
- Renal Diseases and Glomerulopathies
- Antifungal resistance and susceptibility
- Pneumocystis jirovecii pneumonia detection and treatment
- Pediatric Urology and Nephrology Studies
- Central Venous Catheters and Hemodialysis
- Pharmacological Effects and Toxicity Studies
- Kidney Stones and Urolithiasis Treatments
- Muscle and Compartmental Disorders
- Biochemical and Molecular Research
- Polyomavirus and related diseases
- Telemedicine and Telehealth Implementation
- Parvovirus B19 Infection Studies
- Hematopoietic Stem Cell Transplantation
- Acute Kidney Injury Research
Jaslok Hospital
2010-2025
Ion Exchange (India)
2024
Wockhardt Hospitals
2020
Army Hospital Research and Referral
2020
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals
2018
National Hospital
2015
Astellas Pharma (India)
2015
Sir Ganga Ram Hospital
2015
Christian Medical College & Hospital
2015
Christian Medical College
2015
There is a scarcity of data on the consequences coronavirus disease-19 (COVID-19) infections in kidney transplant recipients (KTRs) from emerging countries.Here, we present cohort study 13 centers India including 250 KTR (226 living and 24 deceased donors) with polymerase chain reaction-confirmed COVID-19 positivity March 23, 2020, until September 15, 2020. We detailed demographics, immunosuppression regimen, clinical profile, treatment, outcomes.Median age was 43 years, presented at median...
As the coronavirus disease 2019 (COVID-19) pandemic spread across globe, transplant programs suffered a setback. We report first experience of COVID-19 infection within 1 month living donor kidney (LDKT). describe 2 LDKT recipients who were detected positive for severe acute respiratory syndrome (SARS-CoV-2) at day 19 and 7 posttransplant. They had minimal symptoms diagnosis did not develop any complications or allograft dysfunction. Immunosuppression was de-escalated; however,...
We describe an extremely rare case of fatal cardiac mucormycosis in a renal transplant recipient, clinically manifested by focal myopericarditis and ST-elevation myocardial infarction, due to contiguous mediastinal spread. Cardiac is seen 0.2–1.2% transplants carries unfavorable prognosis despite the timely diagnosis, intensive antifungal therapies, surgical intervention.
There is limited current knowledge on feasibility and safety of kidney transplantation in coronavirus disease-19 (COVID-19) survivors.We present a retrospective cohort study 75 transplants patients who recovered from polymerase chain reaction (PCR)-confirmed COVID-19 performed across 22 transplant centers India July 3, 2020, to January 31, 2021. We detail demographics, clinical manifestations, immunosuppression regimen, laboratory findings, treatment, outcomes. Patients with previous...
BackgroundThere is an enormous knowledge gap on management strategies, clinical outcomes, and follow-up after kidney transplantation (KT) in recipients that have recovered from coronavirus disease (COVID-19).MethodsWe conducted a multi-center, retrospective analysis 23 Indian transplant centres between June 26, 2020 to December 1, 2021 KT who COVID-19 infections. We analyzed biopsy-confirmed acute rejection (AR) incidence used cox-proportional modeling estimate multivariate-adjusted hazard...
Background. There is no robust evidence–based data for ABO-incompatible kidney transplantation (ABOiKT) from emerging countries. Methods. Data 1759 living donor ABOiKT and 33 157 ABO-compatible transplantations (ABOcKT) performed in India between March 5, 2011, July 2, 2022, were included this retrospective, multicenter (n = 25) study. The primary outcomes management protocols, mortality, graft loss, biopsy-proven acute rejection (BPAR). Results. Protocol rituximab 100 (232 [13.18%]), 200...
Background: In the current coronavirus 2019 (COVID-19) pandemic, hemodialysis patients are at increased risk of acquiring COVID-19 infection.Many awaiting transplant may have already contracted infection.Hence, deciding "right time" to is important.Methods: We describe first case report a patient who recovered from severe infection and later successfully underwent living donor ABO incompatible (ABOi) kidney (KT).Results: A 46-year-old man on was planned for ABOi KT, with mother as...
Renal transplantation in patients with malignancy is controversial. generally not considered for multiple myeloma (MM) because of their extremely poor prognosis. There are few reports MM recurrence among kidney transplant recipients. We present a case disease relapse plasmacytoma transplanted kidney. patient extramedullary plasmacytoma, who responded well to chemotherapy and underwent allogenic renal transplantation. He relapsed after 4 years progression plasmacytoma. Despite minimal...
Renal transplant from a HBsAg positive living donor to negative recipient is not routinely done due risk of transmission hepatitis B infection following transplantation. Such donors are usually rejected which further reduces the pool. We report case transplanted with kidney who free chronic on one year follow up. This best our knowledge first reported in India.
Export Introduction: Induction immunosuppression therapy plays a significant role in the prevention of acute rejection renal transplantation. This study aimed to evaluate effectiveness and safety rabbit anti-thymocyte globulin (rATG) used as induction Indian patients undergoing Patients Methods: RISE was multicenter (n = 20), prospective observational cohort aged ≥ 18 years first or repeat transplant receiving rATG part routine management practice. Twelve-month evaluated primary endpoint....
Acute kidney injury (AKI) is a common and severe complication in burns. Preexisting chronic disease (CKD) can make the management more challenging. We present strategy adopted such case, highlighting adaptations fluid resuscitation, dialysis, septicemia prevention. The case involved 2
Nucleoside diphosphate-linked moiety X-type motif 15 (NUDT15) enzyme is a member of the NUDIX hydrolase family and inactivates nucleoside triphosphates.S1–S3 NUDT15 poor metabolizer intermediate phenotypes are at increased risk adverse drug reactions to medications metabolized by because levels exceeding therapeutic range. Apart from azathioprine, another posttransplant medication, ganciclovir also NUDT15.1,2 Valganciclovir, being prodrug ganciclovir, will be NUDT15.