A5007507417- Pharmacological Receptor Mechanisms and Effects
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Receptor Mechanisms and Signaling
- Tryptophan and brain disorders
- Ginger and Zingiberaceae research
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Genetics, Aging, and Longevity in Model Organisms
- Tea Polyphenols and Effects
- Essential Oils and Antimicrobial Activity
- Ginkgo biloba and Cashew Applications
- Alzheimer's disease research and treatments
- Pharmacological Effects of Natural Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Long-Term Effects of COVID-19
- Neuropeptides and Animal Physiology
- Neuroscience and Neuropharmacology Research
- Cancer-related cognitive impairment studies
- Nicotinic Acetylcholine Receptors Study
- GABA and Rice Research
- Phytochemicals and Antioxidant Activities
- Computational Drug Discovery Methods
- Bioactive natural compounds
- Natural Compound Pharmacology Studies
Chulalongkorn University
2016-2025
King's College London
2016
University of Bath
2011
Bacopa monnieri (Linn.) Wettst. has been used in traditional medicine as a drug to enhance and improve memory. In this regard, study aims provide B. monnieri's efficacy neuroprotective nootropic against various neurological diseases. Literatures were collected, following Prisma guidelines, from databases, including Scopus, PubMed, Google Scholar, Science Direct scrutinized using quality scoring system. Means, standard deviations 'n' numbers extracted the metrics analyzed. Jamovi computer...
Epigenetics defines changes in cell function without involving alterations DNA sequence. Neuroepigenetics bridges neuroscience and epigenetics by regulating gene expression the nervous system its impact on brain function. With increase research recent years, it was observed that did not always originate from genetic sequence, which has led to understanding role of neurodegenerative diseases (NDDs) including Alzheimer's disease (AD) Parkinson's (PD). Epigenetic contribute aberrant genes...
Repurposed drugs with host-directed antiviral and immunomodulatory properties have shown promise in the treatment of COVID-19, but few trials studied combinations these agents. The aim this trial was to assess effectiveness affordable, widely available, repurposed used combination for which may be particularly relevant low-resource countries.
The Herb Rhinacanthus nasutus (L.) Kurz, which is native to Thailand and Southeast Asia, has become known for its antioxidant properties. Neuronal loss in a number of diseases including Alzheimer’s disease thought result, part, from oxidative stress. Glutamate causes cell death the mouse hippocampal line, HT-22, by unbalancing redox homeostasis, brought about reduction glutathione levels, amyloid-β been shown induce reactive oxygen species (ROS) production. Here in, we show that ethanol...
Neurodegenerative diseases, such as Alzheimer's disease, cause a great deal of suffering for both patients and carers. Bacopa monnieri (L.) wettst. Is known its memory-enhancing properties, is interest in treating neurodegenerative disease. This study aimed to evaluate B.monnieri against glutamate toxicity, identify whether reduces mitochondrial ER stress, well measure B.monnieri's effect on the life span aging Caenorhabditis elegans. We hypothesized that would prevent cellular oxidative...
Abstract The COVID-19 pandemic caused by the SARS-CoV-2 virus has greatly affected global health. Emerging evidence suggests a complex interplay between Alzheimer’s disease (AD), diabetes (DM), and COVID-19. Given COVID-19’s involvement in increased risk of other diseases, there is an urgent need to identify novel targets drugs combat these interconnected health challenges. Lysophosphatidic acid receptors (LPARs), belonging G protein-coupled receptor family, have been implicated various...
Rhinacanthus nasutus (L.) Kurz (Acanthaceae) is an herb native to Thailand and Southeast Asia, known for its antioxidant properties. Hypoxia leads increase in reactive oxygen species cells a leading cause of neuronal damage. Cell death caused by hypoxia has been linked with number neurodegenerative diseases including some forms dementia stroke, as well the build up which can lead such Huntington’s disease, Parkinson’s disease Alzeheimer’s disease. In this study we used airtight culture...
Plant parts and their bioactive compounds are widely used by mankind for health benefits. Cleistocalyx nervosum var. paniala is one berry fruit, native to Thailand, known exhibit various benefits in vitro. The present study was focused on analyzing the antiaging, stress resistance, neuroprotective effects of C. model system Caenorhabditis elegans using physiological assays, fluorescent imaging, qPCR analysis. results suggest that fruit extract able significantly extend median maximum...
Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are rich source naturally occurring compounds with immense therapeutic potential. Among them, Aquilaria crassna (commonly known as agarwood) is precious fragrant plant extensively used in cosmetics, perfumes, and traditional Asian medicine. However, its neuroprotective role, particularly neuroregeneration, has been minimally explored. This study aimed to investigate...