A5114777849- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Capillary Electrophoresis Applications
- Microwave-Assisted Synthesis and Applications
- Electrocatalysts for Energy Conversion
- Catalytic Processes in Materials Science
- Analytical Chemistry and Chromatography
- Electrochemical Analysis and Applications
- Tea Polyphenols and Effects
- Electrochemical sensors and biosensors
- Catalytic Cross-Coupling Reactions
- Food Quality and Safety Studies
- Enzyme Catalysis and Immobilization
- Mesoporous Materials and Catalysis
- Neurological Disease Mechanisms and Treatments
- Caching and Content Delivery
- Analytical Chemistry and Sensors
- Nanomaterials for catalytic reactions
- Medicinal Plants and Neuroprotection
- Medical Imaging and Pathology Studies
- Medical Imaging Techniques and Applications
- Peptidase Inhibition and Analysis
- Cancer, Hypoxia, and Metabolism
- Consumer Perception and Purchasing Behavior
- Glioma Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
University of Hull
2004-2020
Guangxi Medical University
2011
Tea Research Institute
2007-2009
The Suzuki cross-coupling reaction of aryl halides with phenylboronic acid to form biaryls has been used illustrate the development a microwave based technique capable delivering heat locally heterogeneous Pd-supported catalyst located within micro reactor device. A 10-15 nm gold film patch, on outside surface base glass reactor, was found efficiently assist in heating when irradiated 5-7 W power at 2.45 GHz. Using hydrodynamically pumped system, reactant-catalyst contact times less than 60...
Currently coupled: A clean microreactor-based electrosyntheses in the absence of supporting electrolyte is demonstrated and shown to feature very simple cell geometries. As exemplified for coupling reaction various olefins with benzyl bromides, height microfluidic flow rate are crucial minimization unwanted side products optimization yields (see picture).
A product-scalable, catalytically mediated flow system has been developed to perform Suzuki-Miyaura reactions under a microwave heating regime, in which the volumetric throughput of Pd-supported silica monolith can be used increase quantity product without changing optimal operating conditions. Two monoliths (both 3 cm long), with comparable pore diameters and surface areas, were fabricated 3.2 6.4 mm give capacities 0.205 0.790 mL, respectively. The two functionalized loading 4.5 wt % Pd...
A simple microfluidic reactor system is described for the effective synthesis of enzyme functionalized nanoparticles which offers many advantages over batch reactions, including excellent efficiencies. Better control process parameters in based methodology enables production silica with optimum size efficient immobilization long-term stability. The synthetic approach demonstrated glucose oxidase (GOD) and two different nucleation catalysts similar molecular mass: natural R5 peptide,...
Fließend gekuppelt: Ein einfach aufgebauter Mikroflussreaktor ermöglicht saubere elektrochemische Synthesen, die ohne Elektrolytzusatz auskommen. Am Beispiel der Kupplung von Olefinen mit Benzylbromid wird gezeigt, dass Höhe Durchflusszelle und Flussgeschwindigkeit entscheidend für Minimierung unerwünschter Nebenprodukte Ausbeuteoptimierung sind (siehe Bild).
A simple process for the synthesis of phenyl-2-propanone is described based on a one-step electrochemical acylation reaction, involving direct electroreductive coupling benzyl bromides and acetic anhydride in micro-flow electrolysis cell, equipped with micro-gap Pt electrodes. The technique offered yields typically excess 80% corresponding high levels product selectivity. was also scaled-up by connecting four identical micro cells parallel to increase throughput.
The post-processing of <sup>68</sup>Ga generator eluate by means a novel high capacity cation-exchange silica monolith column has been validated in this work.
We have developed two microfluidic platforms for the electrochemical detection of glucose, using either a screen-printed electrode or wire electrodes, towards quality control testing carbohydrate-based radiotracers used in medical imaging.