Xiaolong Chen

ORCID: 0000-0003-2083-0549
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Musculoskeletal pain and rehabilitation
  • Scoliosis diagnosis and treatment
  • Spinal Fractures and Fixation Techniques
  • Medical Imaging and Analysis
  • Anesthesia and Pain Management
  • Cervical and Thoracic Myelopathy
  • Retinal Diseases and Treatments
  • Pelvic and Acetabular Injuries
  • Spinal Cord Injury Research
  • Pregnancy-related medical research
  • Glaucoma and retinal disorders
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Clinical practice guidelines implementation
  • RNA modifications and cancer
  • Retinopathy of Prematurity Studies
  • Osteoarthritis Treatment and Mechanisms
  • Connective Tissue Growth Factor Research
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Pain Mechanisms and Treatments
  • Corneal Surgery and Treatments
  • Pregnancy and preeclampsia studies
  • Energy, Environment, Economic Growth
  • interferon and immune responses

Capital Medical University
2015-2025

National Clinical Research Center for Digestive Diseases
2022-2025

Liaoning Normal University
2023-2025

Macao Polytechnic University
2024-2025

National Clinical Research
2025

China Medical University
2009-2024

UNSW Sydney
2019-2024

Shanghai Children's Hospital
2018-2024

Shanghai Jiao Tong University
2018-2024

Sutherland Hospital
2019-2024

To characterise the oral microbiome, gut microbiome and serum lipid profiles in patients with active COVID-19 recovered patients; evaluate potential of as a non-invasive biomarker for COVID-19; explore correlations between profile. We collected sequenced 392 tongue-coating samples, 172 faecal samples 155 from Central China East China. characterised molecules, constructed microbial classifiers discovery cohort verified their diagnostic 74 confirmed (CPs) 37 suspected (SPs) IgG positivity....

10.1136/gutjnl-2020-323826 article EN cc-by-nc Gut 2021-03-31

Background: Frailty is recognized as a surrogate for physiological age and has been established valid independent predictor of postoperative morbidity, mortality, complications. ERAS can enhance surgical safety by minimizing stress responses in frail patients, enabling surgeons to discharge patients earlier. However, the question whether what extent frailty impacts post-ERAS outcomes older remains. Materials Methods: An evidence-based program was implemented our center from January 2019....

10.1097/js9.0000000000001594 article EN cc-by-nc-nd International Journal of Surgery 2024-05-09

Abstract Purpose High intensity zones (HIZ) in the lumbar intervertebral disk (IVD) can be associated with degenerative changes which may ultimately manifest as low back pain (LBP). However, relationship between prevalence of HIZ and parameters is still unclear. The purpose this study was to determine spine, analyze independent measured on MRI X-ray association presence LBP. Methods A retrospective review data, radiology reports for 136 consecutively recruited patients, above 18-years-age...

10.1007/s00586-024-08185-x article EN cc-by European Spine Journal 2024-02-21

Neuropathic pain is a severe problem that difficult to treat clinically. Reducing abnormal remodeling of dendritic spines/synapses and increasing the anti-inflammatory effects in spinal cord dorsal horn are potential methods this disease. Previous studies have reported electroacupuncture (EA) could increase threshold after peripheral nerve injury. However, underlying mechanism unclear. P2X7 receptors (P2X7R) mediate activation microglia participate occurrence development neuropathic pain. We...

10.1177/1744806921997654 article EN cc-by-nc Molecular Pain 2021-01-01

This study aims to provide a precise assessment of the distribution educational facilities within Guangdong–Hong Kong–Macao Greater Bay Area, serving as crucial foundation for managing resource allocation and enhancing quality services. Utilizing kernel density analysis, global autocorrelation geographic detectors, this research systematically analyzes spatial characteristics influencing factors in area. The findings reveal significant geographical disparities facility with dense clusters...

10.3390/ijgi13070225 article EN cc-by ISPRS International Journal of Geo-Information 2024-06-27

10.1016/j.bbrc.2018.10.052 article EN Biochemical and Biophysical Research Communications 2018-10-15

Background: Circular RNAs (circRNAs) play vital roles in the modulation of tumor progression. This study explored biological functions circ_0001105 progression osteosarcoma (OS). Methods: qRT-PCR and situ hybridization (ISH) were performed to detect expression status cells tissues. Bioinformatics analysis, dual-luciferase reporter gene assay, Western blot determine relationships among RNAs. The CCK-8, colony formation, EdU, transwell wound healing assays conducted evaluate cell growth,...

10.2147/ott.s234668 article EN OncoTargets and Therapy 2020-02-01

Retinal neovascularization (RNV) is a characteristic pathological finding of retinopathy prematurity (ROP). Cysteine-rich 61 [Cyr61, also known as CCN family member 1 (CCN1)] has been reported to mediate angiogenesis. The aim the present study was investigate mechanisms CCN1/Cyr61-phosphoinositide 3-kinase (PI3K)/AKT signaling in ROP. contribution CCN1 human umbilical vein endothelial cell (HUVEC) proliferation and apoptosis under hypoxic conditions determined using counting kit‑8 (CCK-8)...

10.3892/ijmm.2015.2371 article EN cc-by-nc-nd International Journal of Molecular Medicine 2015-10-12

In the context of high turnover rates in construction industry, team leisure sports activities have been increasingly promoted, with growing attention on their potential impact sustainability workers’ occupational commitment. However, there is a lack systematic research mechanism through which promote This study explores how enhance commitment mediating effect cohesion, integrating perspectives from social psychology and organizational behavior. Data were collected 509 Chinese workers using...

10.3390/buildings15040522 article EN cc-by Buildings 2025-02-08

Based on the panel data of regional GDP balance pollutant and carbon dioxide emissions in 21 cities Guangdong Province from 2006 to 2020, dynamic equilibrium relationship between pollution reduction economy was investigated using a PVAR model. The results were as follows: ① A self-growth mechanism inertia effect exists compared with reduction. ② causal control mainly reflected inhibition discharge economy. response water economic shock changed positive negative, curve air pollutants...

10.13227/j.hjkx.202402014 article EN PubMed 2025-02-08

The present study aims to investigate how the safety cognition bias of high-altitude workers in different age groups construction industry affects their unsafe behaviors. A theoretical framework involving bias, risk-taking propensity, work experience, and behaviors was constructed. empirical analysis conducted using structural equation modeling. results indicate that has a significant positive effect on workers. Risk-taking propensity plays mediating role this relationship, with partial...

10.3390/buildings15060880 article EN cc-by Buildings 2025-03-12
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