A5068521646- Prostate Cancer Treatment and Research
- Radiopharmaceutical Chemistry and Applications
- Prostate Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- HER2/EGFR in Cancer Research
- Urologic and reproductive health conditions
- Colorectal Cancer Surgical Treatments
- Radiomics and Machine Learning in Medical Imaging
- Peptidase Inhibition and Analysis
- Nonmelanoma Skin Cancer Studies
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Cutaneous Melanoma Detection and Management
- Neurological and metabolic disorders
- Schizophrenia research and treatment
- Advances in Oncology and Radiotherapy
- Neurology and Historical Studies
- Cancer Diagnosis and Treatment
St Vincent's Hospital Sydney
2021-2022
St Vincent's Hospital
2022
Gosford Hospital
2022
University of Leeds
2017
<b>Background:</b> Multi-parametric magnetic resonance imaging (mpMRI) is validated for the diagnosis of clinically significant prostate cancer (csPCa). <sup>68</sup>Ga-PSMA -11 PET/CT (PSMA-PET/CT) combined with mpMRI has improved negative predictive value over alone csPCa. The aim this post-hoc analysis PRIMARY study was to evaluate clinical significance patterns intra-prostatic PSMA activity, proposing a 5- point score optimise accuracy PSMA-PET/CT csPCa in low prevalence population....
Breast cancers are most frequently oestrogen receptor (ER) and progesterone (PR) positive [18F]Fluorodeoxyglucose PET-CT (FDG) has lower sensitivity for these subtypes. The gastrin-releasing peptide (GRPR) is overexpressed in ER+/PR+ breast cancers. This study assessed the safety potential of [64Cu]Cu-Sarcophagine (SAR)-Bombesin PET/CT (BBN) re-staging metastatic ER+/PR+/human epidermal growth-factor-2-negative (HER2-) cancer. Seven patients with ER+/PR+/HER2- cancer undergoing staging...
Abstract Aim Mesocolic plane surgery with central vascular ligation produces an oncologically superior specimen following colon cancer resection and appears to be related optimal outcomes. We aimed assess whether a regional educational programme in mesocolic led improvement the quality of specimens. Method Following Capital Zealand areas Denmark, 686 cases primary resected across six hospitals were assessed by grading undertaking tissue morphometry. These compared 263 specimens prior...
18 F-Fludeoxyglucose PET-CT (FDG) is increasingly used to stage breast cancer. Most cancers express the Oestrogen Receptor (ER) and Progesterone (PR), this subtype demonstrates lower activity on FDG imaging. Somatostatin receptors (SSTR) offer a potentially improved radiotracer target for ER+ /PR+ We present first in vivo clinical study comparing 68 Ga-DOTATATE (DOTA) conventional imaging (bone scan diagnostic CT), metastatic human epidermal growth factor receptor 2 (HER2) negative...
To identify whether synchronous reading of multiparametric magnetic resonance imaging (mpMRI) and 68 Ga-PSMA-11 positron emission tomography (PET)/computed (prostate-specific membrane antigen [PSMA-PET]) images can improve diagnostic performance certainty compared with mpMRI/PSMA-PET reported independently synthesized, while also assessing concordance between modalities agreement histopathology.This was a retrospective analysis 100 patients randomly selected from the PRIMARY trial,...
Patel, Neil; Sheehan‐Dare, Gemma; Weir, Justin; Verma, Suman; Fearfield, Louise Author Information
Aim:The aim of this study was to assess the pick-up rate organic brain abnormalities in patients who presented with first episode psychosis (FEP) and impact positive findings on clinical management.Background: First refers time person experiences psychotic symptoms.This includes people have recently had their but can also include those been treated for some not seen any improvement symptoms.
3092 Background: Breast cancers are most frequently oestrogen receptor (ER) and progesterone (PR) positive 18 F-Fluorodeoxyglucose PET-CT (FDG) used in conventional staging of breast cancer has lower sensitivity for these subtypes. Gastrin releasing peptide receptors (GRPR) a potential alternative diagnostic theranostic target ER+/PR+ due to their overexpression GRPR. This phase 1 study aims assess the safety novel radiotracer 64 Cu-Sarcophagine(SAR)-Bombesin (BBN) re-staging recurrent...