Abstract Objective To compare the safety and accuracy of cortical bone trajectory screw placement between robot-assisted fluoroscopy-assisted approaches. Methods This retrospective study was conducted November 2018 June 2020, including 81 patients who underwent (CBT) surgery for degenerative lumbar spine disease. CBT performed by same team experienced surgeons. The were randomly divided into two groups—the group (FA, 44 patients) (RA, 37 patients). Robots orthopedic used in , whereas...

Distraction spinal cord injuries (DSCIs) often occur as the neurological complication of distraction forces following implantation internal fixation devices during scoliosis correction surgery. However, underlying mechanism behind these remains unclear. The present study aimed to explore activation microglia and macrophages, well changes in TLR4-mediated NF-κB MAPK pathway activity after DSCIs Bama miniature pigs. Prior surgical intervention, pigs were randomly divided into three groups:...

Study Design: This was a prospective randomized controlled trial study. Objective: To elucidate clinical and radiographic outcomes complications of cortical bone trajectory (CBT)-screw fixation in patients with osteoporosis at 24-month follow-up to compare the results those after transforaminal lumbar interbody fusion (TLIF) using traditional pedicle screw (PS) fixation. Methods: We enrolled 124 randomly assigned them two groups (each group had 62 participants). The primary outcome rate. S...

(1) Background: The three-dimensional printing (3DP) technique has been reported to be of great utility in spine surgery. purpose this study is report the clinical application personalized preoperative digital planning and a 3DP guidance template treatment severe complex adult spinal deformity. (2) Methods: eight patients with rigid kyphoscoliosis were given surgical simulation based on radiological data. Guidance templates for screw insertion osteotomy designed manufactured according...

Background: Posterior long spinal fusion was the common procedure for adult deformity (ASD). Although application of sacropelvic fixation (SPF), incidence pseudoarthrosis and implant failure is still high in extending to lumbosacral junction (LSJ). To address these mechanical complications, advanced SPF technique by multiple pelvic screws or multirod construct has been recommended. This first study compare biomechanical performance combining other constructs augmentation LSJ surgery through...

The incidence of distraction spinal cord injury (DSCI), which results from ischemia due to vascular compromise and tract disturbances, remains high. Furthermore, because no ideal animal model that mimics DSCI in clinical settings is available thus far, the related molecular mechanisms underlying remain unclear. Thus, this study aimed establish a porcine investigate neuroinflammation apoptosis these pigs. Before surgery, all pigs were randomly divided into three groups: sham group, osteotomy...

We evaluated long-term outcomes (radiographic parameters and pulmonary function) at a minimum follow-up of 5 years after use dual growing rods (DGRs) to treat severe early-onset scoliosis (sEOS).Among total 112 patients who were diagnosed with (EOS) treated DGRs between 2006 2015, 52 had sEOS, major Cobb angle >80°. Of these patients, 39 complete radiographic function test results included. The the curve, T1-S1 height, T1-T12 maximum kyphosis in sagittal plane measured on radiographs....

The optimized enhanced recovery after surgery (ERAS) pathway for adolescent idiopathic scoliosis (AIS) patients has not been comprehensively described. purpose of the study was to explore feasibility and efficacy an integral process ERAS protocol in posterior spinal fusion (PSF) AIS without three-column osteotomy.Based on inclusion exclusion criteria, a total 90 who underwent PSF were enrolled study. Forty-five followed traditional (TP) perioperative care 45 treated with designed implemented...

Study Design. A retrospective study. Objective. The aim of this study was to identify associated risk factors distal adding-on in severe and rigid scoliosis. Summary Background Data. Previous work has evaluated the challenges treatment patients with scoliosis risks complications. Furthermore, although several studies have investigated postoperative attendant Lenke type 1A scoliosis, very few focused on Methods. In study, 48 consecutive underwent posterior spinal fusion surgery. parameters...

The aim of this study was to use diffusion tensor imaging (DTI) investigate changes in metrics patients with cervical spondylotic myelopathy (CSM) up five years after decompressive surgery. We correlated these clinical outcomes as scored by the Modified Japanese Orthopedic Association (mJOA) method, Neck Disability Index (NDI), and Visual Analogue Scale (VAS).We used multi-shot, high-resolution, (ms-DTI) change anterior interbody discectomy fusion (ACDF). High signal intensity identified on...

Background. Severe and rigid scoliosis poses significant challenges in surgical correction, innovative approaches are continually sought to enhance effectiveness ensure patient safety. Halo-gravity traction (HGT) continues be a vital tool managing severe spinal conditions, offering nonsurgical or preoperative approach address deformities. However, the correction effect that HGT can achieve for deformity is currently unclear impact of on selection osteotomy grade was still unknown. Methods. A...

Although surgery prevents the progression of deformity and maintains overall balance spine in congenital scoliosis (CS) patients, it is associated with a high risk perioperative complications. Pulmonary complication one most common This retrospective study aimed to investigate factors for pulmonary complications CS patients after posterior spinal instrumentation fusion.Analysis consecutive who underwent fusion was performed. Preoperative clinical data, intraoperative variables, radiographic...

This was a retrospective observational study.We aimed to characterize the feasibility of assessing accuracy cortical bone trajectory (CBT) screw placement in midline lumbar interbody fusion using traditional pedicle insertion evaluation system based on computed tomography (CT).Since Santoni and colleagues proposed CBT as an alternative approach for treatment degenerative disease, has been biomechanically clinically investigated detail. The reported misplacement rate 0%-12.5%. Therefore,...

Retrospective case-control study.We aimed to evaluate the value of 3-dimensional printing (3DP) spine model in surgical treatment severe spinal deformity since prosperous development 3DP technology.Severe scoliosis or hyper-kyphosis patients underwent posterior fixation and fusion surgery using models were reviewed (3DP group). Spinal surgeries operated by free-hand screw implantation during same period selected as control group after propensity score matching (PSM). The correction rate,...

Purpose We performed a bioinformatics analysis to identify the key genes that were differentially expressed between degenerative intervertebral disc (IVD) cells with and without exposure interleukin-1β explore related signaling pathways interaction networks. Methods The microarray data downloaded from Gene Expression Omnibus (27,494). Then, analyses of gene ontology, pathways, networks for (DEGs) conducted using tools including Database Annotation, Visualization, Integrated Discovery,...