Bowen Lian

ORCID: 0000-0003-2132-5229
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About
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Research Areas
  • Optical Polarization and Ellipsometry
  • Epigenetics and DNA Methylation
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Cancer, Hypoxia, and Metabolism
  • Semiconductor materials and devices
  • Calpain Protease Function and Regulation
  • Integrated Circuits and Semiconductor Failure Analysis
  • Sirtuins and Resveratrol in Medicine
  • Mesenchymal stem cell research
  • Signaling Pathways in Disease
  • Developmental Biology and Gene Regulation
  • Optical Systems and Laser Technology
  • Orthodontics and Dentofacial Orthopedics
  • Dental Research and COVID-19
  • Cancer-related molecular mechanisms research
  • Advancements in Semiconductor Devices and Circuit Design
  • Dental materials and restorations
  • Ferroptosis and cancer prognosis
  • Histone Deacetylase Inhibitors Research
  • Adipose Tissue and Metabolism
  • Spectroscopy and Chemometric Analyses
  • Optical measurement and interference techniques
  • Photoreceptor and optogenetics research

China Medical University
2020-2022

Institute of Optics and Electronics, Chinese Academy of Sciences
2022

Chinese Academy of Sciences
2022

University of Chinese Academy of Sciences
2022

Stomatology Hospital
2021

First Affiliated Hospital of Zhengzhou University
2020

Guangdong Pharmaceutical University
2018

Semiconductor Manufacturing International (China)
2016

Heart failure (HF) affects over 26 million people worldwide, yet the pathologies of this complex syndrome have not been completely understood. Here, we investigated involvement deacetylase Sirtuin 1 (Sirt1) in HF and its downstream signaling pathways. A model was induced by ligation left coronary artery rats, where factors associated with ventricular echocardiography, heart hemodynamics mass indexes were recorded. Collagen volume fraction tissues determined Masson's trichrome staining. Cell...

10.18632/aging.103640 article EN cc-by Aging 2020-11-18

Ferroptosis is type of programmed cell death, which known to be involved in certain cancers. Notch3 signaling reported the tumorigenesis non‐small‐cell lung cancer (NSCLC) and regulates iron metabolism, lipid synthesis, oxidative stress some tissues. However, whether ferroptosis unclear. In this study, we found that inhibitors, ferrostatin‐1 liproxstatin‐1, protected against death induced by knockdown initiated NSCLC cells increasing reactive oxygen species (ROS) levels, peroxidation, Fe 2+...

10.1002/2211-5463.13393 article EN cc-by FEBS Open Bio 2022-03-08

Renal cell carcinoma (RCC) is one of the most common malignant tumors urinary system. Although deregulation Notch signaling pathway in RCC and involved tumorigenic process, exact role Notch3 its underlying molecular mechanism RCC, particularly hypoxia, remain unknown. In present study, RO4929097, a inhibitor, was used to alter NICD3 expression. A Cell Counting Kit-8 assay, EdU incorporation colony formation flow cytometry western blot analysis were investigate effects altered expression on...

10.3892/ol.2020.12242 article EN Oncology Letters 2020-10-22

A time-integration imaging polarimeter with continuous rotating retarder is presented, and its full-Stokes retrieving configuration optimization are also demonstrated. The mathematical expression between the vector light intensities derived. As a result, state of polarization incident can be retrieved by only one matrix calculation. However, modulation deviates from initial well-conditioned status due to time integration. Thus, we re-optimize nominal angles for special retardance 132° 90° an...

10.3390/s22134733 article EN cc-by Sensors 2022-06-23

Poly-connected MOSFETs can reduce chip area due to replacing some metal layer routing. Compared with conventional MOS, resistance of connecting poly (P2) is an additional factor which impacts MOS electrical performance, besides LDD and source/drain parasitic resistance. Conventional extraction method requires a series different gate length test structures. A new demonstrated here, that extract the from forward biased current vs. voltage characteristics drain/bulk junction diode based on...

10.1109/cstic.2016.7463902 article EN 2022 China Semiconductor Technology International Conference (CSTIC) 2016-03-01
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