A5071040805- Ethics in Clinical Research
- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Grief, Bereavement, and Mental Health
- Drug Transport and Resistance Mechanisms
- Memory, Trauma, and Commemoration
- Migration, Health and Trauma
- Housing, Finance, and Neoliberalism
- Cancer Immunotherapy and Biomarkers
- Ethics and bioethics in healthcare
- Inflammatory Biomarkers in Disease Prognosis
- Identity, Memory, and Therapy
- Biomedical Ethics and Regulation
- Islamic Studies and Radicalism
- Multiple Myeloma Research and Treatments
- Terrorism, Counterterrorism, and Political Violence
- Immune Cell Function and Interaction
- Amyloidosis: Diagnosis, Treatment, Outcomes
Manchester Academic Health Science Centre
2025
University of Manchester
2025
Greater Manchester Mental Health NHS Foundation Trust
2025
Emory University
2018-2023
Pennine Care NHS Foundation Trust
2020
Tufts University
2014
Background Optimal prognostic and predictive biomarkers for patients with advanced‐stage cancer who received immunotherapy (IO) are lacking. Inflammatory markers, such as the neutrophil‐to‐lymphocyte ratio (NLR), monocyte‐to‐lymphocyte (MLR), platelet‐to‐lymphocyte (PLR), readily available. The authors investigated association between these markers clinical outcomes of IO. Methods A retrospective review was conducted 90 advanced treatment on phase 1 trials IO‐based regimens. NLR, MLR, PLR...
Muslims comprise a significant and growing percentage of the population in United Kingdom. Muslim youth this country face unique set challenges related to cultural identity acculturation. Because perceived discrimination frequent issues, they are often considered at risk for radicalization. This article presents theoretical frameworks identity, acculturation, radicalization outlines implications these concepts have social work practice with The provides suggestions recommendations concerning...
8057 Background: Myeloma patients (pts) with renal insufficiency (RI) have inferior disease outcomes; up to 50% present acute kidney injury (AKI). AKI results from light chain-induced cast nephropathy; physicochemical properties (self-association, aggregate formation) may determine severity. Daratumumab has extensive data in myeloma, reduces circulating chains, preserves function AL amyloidosis, and non-renal clearance. We hypothesized early therapy daratumumab VRD normalize myeloma-induced...
Abstract Background: Racial and ethnic minority populations are consistently under-represented in oncology clinical trials despite comprising a disproportionate share of cancer burden. Due part to difficulties associated with participation, phase 1 (P1) pose unique challenge opportunity for inclusion. Here we examine the sociodemographics P1 trial patients at an NCI-designated Comprehensive Cancer Center compared all treated center, new diagnoses metropolitan Atlanta (ATL), state Georgia...
Abstract Racial and ethnic minority populations are consistently under-represented in oncology clinical trials despite comprising a disproportionate share of cancer burden. Phase I pose unique challenge opportunity for inclusion. Here we compared the sociodemographic characteristics patients participating phase 1 National Cancer Institute ( NCI)-designated comprehensive center to all at center, with new diagnosis metropolitan Atlanta diagnoses state Georgia. From 2015 2020, 2325 (43.4%...
e18591 Background: Racial and ethnic minority populations are consistently under-represented in oncology clinical trials despite comprising a disproportionate share of cancer burden. Due part to difficulties associated with participation, phase 1 pose unique challenge opportunity for inclusion. Here we examine the sociodemographics trial patients at an NCI-designated Comprehensive Cancer Center compared all treated center, new diagnoses metropolitan Atlanta, state Georgia (GA). Methods:...