A5048724128- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Cancer-related Molecular Pathways
- RNA modifications and cancer
- Cell death mechanisms and regulation
- Streptococcal Infections and Treatments
- HIV/AIDS oral health manifestations
- Laser Applications in Dentistry and Medicine
- Nuclear Structure and Function
- Cancer-related molecular mechanisms research
- Cancer-related gene regulation
- Oral health in cancer treatment
- Periodontal Regeneration and Treatments
China Medical University
2016-2023
Previous studies have proved that periodontitis is an independent risk factor of oral squamous cell carcinoma (OSCC) epidemiologically. Along with the important role microbiota in cancer process and specific anatomical position, our study explored microbial composition functions gingival (GSCC). GSCC patients (n = 10), matched 15), healthy individuals 15) were recruited. Saliva, subgingival plaque, tongue dorsum, buccal mucosa, cancerous tissue, paracancerous tissue samples collected. 16S...
Abstract Ulcerative Colitis (UC) has been reported to be related Porphyromonas gingivalis ( P. ). peptidylarginine deiminase (PPAD), a virulence factor released by , is known induce inflammatory responses. To explore the pathological relationships between PPAD and UC, we used homologous recombination technology construct strain in which gene was deleted (Δ ppad ) Δ restored (comΔ C57BL/6 mice were orally gavaged with saline, ppad, or comΔ twice week for entire 40 days (days 0−40), then, UC...