A5091831155- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Mast cells and histamine
- Autoimmune Neurological Disorders and Treatments
- Ocular Oncology and Treatments
USF Health Byrd Alzheimer's Institute
2023
University of South Florida
2020-2022
The aim of this study was to determine the roles collagen XII in regulation stromal hierarchical organization, keratocyte and corneal mechanics.The temporal spatial expression at postnatal days 4, 10, 30, 90, 150 were evaluated wild-type (WT) mice. role organization analyzed by measuring fibril diameter density, as well lamellar structure, within ultrastructural micrographs obtained from WT XII-deficient mice (Col12a1-/-). Keratocyte morphology networks assessed using actin staining with...
Every tissue has an extracellular matrix (ECM) with certain properties unique to it - the 'niche' that are necessary for normal function. A distinct specific population of quiescent keratocan-expressing keratocytes populate corneal stroma during homeostasis maintain However, wound healing, when there is alteration niche conditions, undergo apoptosis, and activated fibroblasts myofibroblasts attempt restore integrity It unknown what fate temporary after healing process resolved. In this...