Raffaella Gandolfi

ORCID: 0000-0003-2145-8574
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About
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Research Areas
  • Enzyme Catalysis and Immobilization
  • Microbial Metabolic Engineering and Bioproduction
  • Asymmetric Hydrogenation and Catalysis
  • Chemical Synthesis and Analysis
  • Steroid Chemistry and Biochemistry
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Carbohydrate Chemistry and Synthesis
  • Analytical Chemistry and Chromatography
  • Cyclopropane Reaction Mechanisms
  • Pharmacogenetics and Drug Metabolism
  • Biofuel production and bioconversion
  • Synthetic Organic Chemistry Methods
  • Microbial metabolism and enzyme function
  • Chemical synthesis and alkaloids
  • Microbial Natural Products and Biosynthesis
  • Microbial Metabolites in Food Biotechnology
  • Synthesis of β-Lactam Compounds
  • Biochemical and biochemical processes
  • Asymmetric Synthesis and Catalysis
  • Chemical Reactions and Isotopes
  • Algal biology and biofuel production
  • Adsorption and biosorption for pollutant removal
  • Oxidative Organic Chemistry Reactions
  • Diabetes Treatment and Management
  • Crystallization and Solubility Studies

University of Milan
2014-2024

Mylan (Switzerland)
2017

Milano University Press
2017

Mylan (South Africa)
2015-2016

University of Trieste
2001

The site of formation kinins in the nephron was determined by stop-flow studies dogs. Klinin, inulin, sodium, potassium concentrations were measured fractions collected during procedures. In addition, three 17 experiments, kallikrein activity also measured. highest kinin concentration after correction for water reabsorption found that probably trapped distal part nephron. Either one or two peak located either fraction overlapping (in instance) coming prior to with potassium. This first...

10.1152/ajprenal.1978.234.1.f36 article EN AJP Renal Physiology 1978-01-01

The development of molecular carriers able to carry molecules directly into the cell is an area intensive research. Cationic nanoparticles are effective delivery systems for several classes molecules, such as anticancer agents, oligonucleotides and antibodies. Indeed, a cationic charge on outer surface allows rapid cellular uptake together with possibility carrying negatively charged molecules. In this work, we studied self-assembly ultra-short ααβ-tripeptide containing l-Arg-l-Ala sequence...

10.1039/c7ob01693j article EN Organic & Biomolecular Chemistry 2017-01-01

Abstract The possibility of obtaining an efficient artificial imine reductase was investigated by introducing a chiral cofactor into metalloenzymes based on biotin–streptavidin technology. In particular, biotinylated 1,3‐diamine ligand in coordination with iridium(III) complex developed. Optimized chemogenetic studies afforded positive results the stereoselective reduction cyclic imine, salsolidine precursor, as standard substrate access to both enantiomers. Various factors such pH,...

10.1002/cctc.201600116 article EN ChemCatChem 2016-04-05

A new efficient synthesis of 1,3-diamines was realized and their ruthenium(<sc>ii</sc>) complexes were studied in ATH aqueous media.

10.1039/c5nj00110b article EN New Journal of Chemistry 2015-01-01

Abstract Glycopeptide antibiotics, such as vancomycin and teicoplanin, are used to treat life‐threatening infections caused by multidrug‐resistant Gram‐positive pathogens. They inhibit bacterial cell wall biosynthesis binding the D ‐Ala‐ ‐Ala C‐terminus of peptidoglycan precursors. Vancomycin‐resistant bacteria replace dipeptide with ‐Lac depsipeptide, thus reducing affinity antibiotics their molecular targets. Herein, studies interaction teicoplanin‐like A40926, semisynthetic derivatives...

10.1002/chem.201303310 article EN Chemistry - A European Journal 2014-05-07

Hybrid catalysts were developed from the Cu(<sc>i</sc>) binding domain of Ctr1 protein and their activity was evaluated in an asymmetric Henry reaction.

10.1039/c6ra16255j article EN RSC Advances 2016-01-01
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