A5053354422- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- RNA modifications and cancer
- PARP inhibition in cancer therapy
- Platelet Disorders and Treatments
- Immune responses and vaccinations
- Connective tissue disorders research
- DNA Repair Mechanisms
- Ginkgo biloba and Cashew Applications
- Low-power high-performance VLSI design
- Cellular transport and secretion
- Renal and related cancers
- SARS-CoV-2 and COVID-19 Research
- Astronomical and nuclear sciences
- RNA regulation and disease
- Alzheimer's disease research and treatments
- COVID-19 Clinical Research Studies
- Porphyrin Metabolism and Disorders
- Inflammasome and immune disorders
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Polyamine Metabolism and Applications
- Gout, Hyperuricemia, Uric Acid
- Neuroscience and Neural Engineering
- Cell Adhesion Molecules Research
Kayseri Eğitim ve Araştırma Hastanesi
2024
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2022-2023
Sağlık Bilimleri Üniversitesi
2022-2023
Erciyes University
2019-2022
<b><i>Introduction:</i></b> The Witteveen-Kolk syndrome (WITKOS) (OMIM: 613406) is a heterogeneous emerging disorder caused by pathogenic variants or microdeletions encompassing the <i>SIN3A</i> gene (SIN3 Transcription Regulator Family Member A). It characterized distinctive facial features, developmental delay, intellectual disability, microcephaly, short stature, and subtle anomalies on brain magnetic resonance imaging (MRI). To date, about 50 patients...
This study aims to evaluate the ABCA4 variants in patients diagnosed with Stargardt disease.
BackgroundEssential tremor (ET) is the most common disease among movement disorders. Genes such as essential 1-4 (ETM 1-4), HS1-binding protein-3 (HS1BP3), dopamine receptor D3 (DRD3), leucine-rich repeat and Ig domain containing 1 (LINGO1), glial high affinity glutamate transporter member 2 (SLC1A2), FUS, temperature requirement A2 (HTRA2) TENM4 had been shown to be responsible for genetic inheritance of disease. The aim present study was investigate effect propranolol on expression DRD3,...
Abstract Background Alport syndrome (AS) is the second most prevalent genetic cause of kidney failure, behind autosomal-dominant polycystic disease, affecting at least one in 5000 individuals worldwide. AS caused by COL4A3, COL4A4, and COL4A5 mutations. It characterized as three distinct disorders type IV collagen 3/4/5 based on a evaluation: X-linked, autosomal, digenic. About two-thirds cases are X-linked (XLAS), 15% autosomal recessive (ARAS), 20% dominant (ADAS). The spectrum phenotypes...
Alzheimer's disease (AD) is a neurodegenerative that characterized by devastating decline in cognitive activities among all types of dementia, and it severely affects the quality life. Late-onset AD (LOAD) occurs after age 65 years develops sporadically. Although aging comes first along main risk factors underlying LOAD, disease-causing susceptibility genes have been associated with pathogenesis. In our study, we included PARP1 , POLB HTRA2 SLC1A2 HS1BP3 DRD3 to be investigated LOAD patients...
Abstract Objective: Recent advances have contributed to a better understanding of the shared and specific roles HLA alleles in outcome Covid-19 disease. We aimed determine if severe prognosis could be predicted. Methods: patients were divided into (n=30) non-severe (n=29) patient groups. All patients’ demographic, clinical, laboratory, treatment data collected analyzed. Class I/II loci (A, B, C DRB1, DQB1, DQA1) studied healthy controls (n=30), outcomes compared. Results: From demographic...
Background Essential tremor (ET) is the most common movement disorder. Propranolol a first-line medication for ET. We aimed to evaluate effect of propranolol on expression poly (ADP-ribose) polymerase 1 (PARP1) and DNA beta (POLB) genes, which are known be related neurodegenerative diseases, in patients with MethodsThirty-five healthy volunteers thirty-five followed up essential tremors were included non-randomized control experimental study. Expressions PARP1 POLB genes compared between...