- Inflammatory Myopathies and Dermatomyositis
- Muscle and Compartmental Disorders
- Neurogenetic and Muscular Disorders Research
- thermodynamics and calorimetric analyses
- Muscle Physiology and Disorders
- Salivary Gland Disorders and Functions
- Nutrition and Health in Aging
- Muscle metabolism and nutrition
- Sleep and Work-Related Fatigue
- Genetic Neurodegenerative Diseases
- Heterotopic Ossification and Related Conditions
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- GDF15 and Related Biomarkers
- Obstructive Sleep Apnea Research
- Eosinophilic Disorders and Syndromes
- Exercise and Physiological Responses
- Protein Hydrolysis and Bioactive Peptides
- Systemic Sclerosis and Related Diseases
Emory University
2024
University College London
2010-2013
Newcastle University
2012-2013
University of Newcastle Australia
2013
Nerve Centre
2012
John Radcliffe Hospital
2012
MRC Prion Unit
2012
Centre for Life
2012
National Hospital for Neurology and Neurosurgery
2010
Objective To assess the effects of a Vicia faba protein hydrolysate (VFH) on muscular strength and endurance when combined with resistance training for 56 days compared exercise alone in mixed population. Design A double-blind placebo-controlled parallel trial. Participants 72 healthy men women aged 19–40, stratified 1:1 ratio by gender. were excluded if they performed >3 hours per week 6 months prior. Setting Ontario, Canada. Study KGK Science from August 2023 to January 2024....
<h3>Background</h3> Sporadic inclusion body myositis (IBM) is the commonest idiopathic inflammatory myopathy occurring in patients over age of 50 years. IBM muscle displays and degenerative features. Previous trials have only involved agents directed purely at component pathology all were ineffective. Modulating cytoprotective "heat shock response" (HSR) represents a therapeutic strategy through which detrimental aspects both inflammation degeneration could be dampened. Arimoclomol an orally...
Abstract Background There is a dearth of research inclusive African Americans living with obstructive sleep apnea (OSA) despite differences in symptom presentations compared to non-Hispanic White patient populations. Less known regarding the potential effect comorbidities, such as hypertension, on commonly reported symptoms, fatigue, and their association inflammatory biomarkers. Objective This longitudinal pilot study aimed characterize fatigue among newly diagnosed OSA discern peripheral...
<h3>Background</h3> Inclusion body myopathy with dementia and Paget disease of bone (IBMPFD) myofibrillar myopathies (MFM) are genetically determined that can mimic sporadic Body Myositis (sIBM), especially if the phenotype is incomplete (eg, skeletal muscle involvement only), there no family history (either because a mutation arises in germ line or parents was unrecognised) histological features overlap those sIBM. It therefore possible some sIBM cases may be caused by undetected mutations...
<h3>Background</h3> There is now clear evidence that supports the health promoting and disease preventing benefits of physical activity. To date, little research has been undertaken to evaluate activity levels in primary Sjögren’s syndrome (PSS) patients. Many symptoms PSS such as musculoskeletal pain fatigue may affect ability desire participate <h3>Objectives</h3> individuals with its relationship other clinical features PSS. <h3>Methods</h3> Self-reported from 273 patients were collected...
<h3>Objective</h3> To assess the clinical features and course of sporadic Inclusion body myositis (sIBM) in a prospective cohort patients diagnosed with definite or probable sIBM, according to Griggs criteria. <h3>Methods</h3> Clinical data, muscle testing, myometry IBM functional rating scale (FRS) were collected standardised protocol (IBM-Net) at baseline (n=42) 1-year follow-up (n=13). <h3>Results</h3> The male:female ratio was 2:1, mean age examination 68 years (range 60–95) disease...